Page last updated: 2024-08-26

tretazicar and Prostatic Neoplasms

tretazicar has been researched along with Prostatic Neoplasms in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (77.78)29.6817
2010's0 (0.00)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Ay, M; Çelik, A; Gülhan, ÜG; Güngör, T; Hacıoğlu, N; Köçkar, F; Önder, FC; Tok, TT; Tokay, E1
Ay, M; Çelik, A; Güngör, T; Güven Gülhan, Ü; Hacıoğlu, N; Köçkar, F; Tokay, E1
Ashdown, D; Bonney, S; Chester, J; Collins, SI; Doherty, A; Hull, D; James, ND; Leung, H; Mautner, V; Patel, P; Peers, E; Pineda, RG; Searle, PF; Wallace, DM; Young, JG; Young, LS1
James, N; Mautner, V; Onion, D; Patel, P; Pineda, RG1
Masai, M; Sato, N1
Bangma, CH; Irvine, AS; Kraaij, R; Lipinski, KS; Mills, KH; Mountain, A; Pelech, S; Todryk, SM1
Green, NK; James, ND; Mautner, V; Searle, PF; Young, JG; Young, LS1
James, ND; Latham, JP; Mautner, V; Searle, PF1
Djeha, AH; Harris, PA; Kerr, DJ; Leung, H; Mountain, A; Searle, PF; Thomson, TA; Wrighton, CJ; Young, LS1

Reviews

1 review(s) available for tretazicar and Prostatic Neoplasms

ArticleYear
[The trends in new drugs for the prostate cancer].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 11

    Topics: Adenoviridae; Androgen Antagonists; Antibodies, Monoclonal; Antineoplastic Agents; Aziridines; Cancer Vaccines; Drug Design; Flurbiprofen; Genetic Therapy; Genetic Vectors; Gonadotropin-Releasing Hormone; Goserelin; Humans; Leuprolide; Male; Oligonucleotides, Antisense; Panitumumab; Prostate-Specific Antigen; Prostatic Neoplasms

2002

Trials

2 trial(s) available for tretazicar and Prostatic Neoplasms

ArticleYear
A phase I/II clinical trial in localized prostate cancer of an adenovirus expressing nitroreductase with CB1954 [correction of CB1984].
    Molecular therapy : the journal of the American Society of Gene Therapy, 2009, Volume: 17, Issue:7

    Topics: Adenoviridae; Aged; Aged, 80 and over; Antineoplastic Agents; Aziridines; Genetic Therapy; Genetic Vectors; Humans; Male; Middle Aged; Nitroreductases; Prodrugs; Prostatic Neoplasms

2009
Antivector and tumor immune responses following adenovirus-directed enzyme prodrug therapy for the treatment of prostate cancer.
    Human gene therapy, 2009, Volume: 20, Issue:11

    Topics: Adenoviridae; Aziridines; Enzyme-Linked Immunosorbent Assay; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Humans; Interferon-gamma; Male; Nitroreductases; Prodrugs; Prostate-Specific Antigen; Prostatic Neoplasms; T-Lymphocytes

2009

Other Studies

6 other study(ies) available for tretazicar and Prostatic Neoplasms

ArticleYear
Prodrugs for nitroreductase-based cancer therapy-3: Antitumor activity of the novel dinitroaniline prodrugs/Ssap-NtrB enzyme suicide gene system: Synthesis, in vitro and in silico evaluation in prostate cancer.
    European journal of medicinal chemistry, 2020, Feb-01, Volume: 187

    Topics: Aniline Compounds; Antineoplastic Agents; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Genetic Therapy; Humans; Male; Models, Molecular; Molecular Structure; Nitroreductases; Prodrugs; Prostatic Neoplasms; Structure-Activity Relationship

2020
Prodrugs for nitroreductase based cancer therapy-4: Towards prostate cancer targeting: Synthesis of N-heterocyclic nitro prodrugs, Ssap-NtrB enzymatic activation and anticancer evaluation.
    Bioorganic chemistry, 2020, Volume: 105

    Topics: Antineoplastic Agents; Aziridines; Colletotrichum; Complex Mixtures; Drug Screening Assays, Antitumor; Enzyme Activation; Enzyme Inhibitors; Fermentation; Fused-Ring Compounds; Heterocyclic Compounds; Humans; Male; Nitro Compounds; Nitroreductases; Polyketides; Prodrugs; Prostatic Neoplasms; Structure-Activity Relationship

2020
Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumour immunity.
    Cancer immunology, immunotherapy : CII, 2006, Volume: 55, Issue:3

    Topics: Adenoviridae; Animals; Antineoplastic Agents; Aziridines; Cell Line, Tumor; Genetic Therapy; Genetic Vectors; HSP70 Heat-Shock Proteins; Immunotherapy; Male; Mice; Mice, Inbred C57BL; Necrosis; Nitroreductases; Prostatic Neoplasms; Proteomics

2006
Combining gene and immunotherapy for prostate cancer.
    Prostate cancer and prostatic diseases, 2008, Volume: 11, Issue:2

    Topics: Adenocarcinoma; Adenoviridae; Animals; Antineoplastic Agents; Aziridines; Biotransformation; Combined Modality Therapy; Defective Viruses; Escherichia coli Proteins; Genes, Synthetic; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Granulocyte-Macrophage Colony-Stimulating Factor; Immunotherapy; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Transplantation; Nitroreductases; Prodrugs; Prostatic Neoplasms; Recombinant Proteins; Specific Pathogen-Free Organisms

2008
Prostate-specific antigen promoter/enhancer driven gene therapy for prostate cancer: construction and testing of a tissue-specific adenovirus vector.
    Cancer research, 2000, Jan-15, Volume: 60, Issue:2

    Topics: Adenoviridae; Androgens; Antineoplastic Agents; Aziridines; Cell Survival; Colonic Neoplasms; Coloring Agents; Cytomegalovirus; Enhancer Elements, Genetic; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Humans; Jurkat Cells; Kinetics; Luciferases; Luminescent Proteins; Male; Oxazines; Polymerase Chain Reaction; Prodrugs; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Recombinant Fusion Proteins; Tissue Kallikreins; Transfection; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Xanthenes

2000
Combined adenovirus-mediated nitroreductase gene delivery and CB1954 treatment: a well-tolerated therapy for established solid tumors.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2001, Volume: 3, Issue:2

    Topics: Adenoviridae; Animals; Antineoplastic Agents; Aziridines; Carcinoma, Hepatocellular; Colorectal Neoplasms; Dose-Response Relationship, Drug; Escherichia coli; Gene Transfer Techniques; Genetic Therapy; Head and Neck Neoplasms; Humans; Liver Neoplasms; Luciferases; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nitroreductases; Prodrugs; Prostatic Neoplasms; Transduction, Genetic; Transfection; Tumor Cells, Cultured

2001