Compounds > tretazicar
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tretazicar and Ovarian Neoplasms

tretazicar has been researched along with Ovarian Neoplasms in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's8 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Minchin, RF; Mitchell, DJ1
Hyde, EI; Jarrom, D; Searle, PF; Vass, SO; Wilson, WR1
Anderson, CJ; Bilsland, AE; Evans, TR; Fletcher-Monaghan, AJ; Ganly, I; Keith, WN; Knox, RJ; McGregor, F; Plumb, JA1
Kerr, DJ; Milner, AE; Palmer, DH; Young, LS1
Grove, JI; Guise, C; Hyde, EI; Lovering, AL; Race, PR; Searle, PF; White, SA; Wrighton, CJ1
Friedlos, F; Marais, R; Schepelmann, S; Spooner, R1
Green, NK; Harris, PA; Kerr, DJ; Mautner, V; Searle, PF1
Bhide, SA; Harrington, KJ; Melcher, AA; Menghistu, T; Pandha, HS; Searle, PF; Twigger, KR; Vile, RG; White, CL1
Ford, MJ; Friedlos, F; Gilligan, MG; Kerr, DJ; McNeish, IA; Searle, PF; Springer, CJ; Weedon, SJ; Young, LS1
Ford, MJ; Gilligan, MG; Green, NK; Kerr, DJ; Mautner, V; McNeish, IA; Searle, PF; Young, LS1

Other Studies

10 other study(ies) available for tretazicar and Ovarian Neoplasms

ArticleYear
E. coli nitroreductase/CB1954 gene-directed enzyme prodrug therapy: role of arylamine N-acetlytransferase 2.
    Cancer gene therapy, 2008, Volume: 15, Issue:11

    Topics: Analysis of Variance; Antineoplastic Agents; Arylamine N-Acetyltransferase; Aziridines; Blotting, Western; Cell Line, Tumor; Cell Survival; DNA Primers; Drug Therapy; Escherichia coli; Female; Flow Cytometry; Humans; Hydroxylamines; Inhibitory Concentration 50; Nitroreductases; Ovarian Neoplasms; Plasmids; Prodrugs; Sulfotransferases

2008
E. coli NfsA: an alternative nitroreductase for prodrug activation gene therapy in combination with CB1954.
    British journal of cancer, 2009, Jun-16, Volume: 100, Issue:12

    Topics: Adenoviridae; Antineoplastic Agents; Aziridines; Cell Survival; Chromatography, High Pressure Liquid; Combined Modality Therapy; Escherichia coli; Escherichia coli Proteins; Female; Genetic Therapy; Genetic Vectors; Humans; Nitroreductases; Ovarian Neoplasms; Prodrugs; Tumor Cells, Cultured

2009
Selective ablation of human cancer cells by telomerase-specific adenoviral suicide gene therapy vectors expressing bacterial nitroreductase.
    Oncogene, 2003, Jan-23, Volume: 22, Issue:3

    Topics: Adenocarcinoma; Adenoviridae; Animals; Antineoplastic Agents; Aziridines; Bacterial Proteins; Base Sequence; DNA-Binding Proteins; Drug Resistance, Neoplasm; Female; Genetic Therapy; Genetic Vectors; Humans; Male; Mice; Mice, Nude; Molecular Sequence Data; Neoplasms; Nitroreductases; Ovarian Neoplasms; Promoter Regions, Genetic; Telomerase; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2003
Mechanism of cell death induced by the novel enzyme-prodrug combination, nitroreductase/CB1954, and identification of synergism with 5-fluorouracil.
    British journal of cancer, 2003, Sep-01, Volume: 89, Issue:5

    Topics: Adenoviridae; Antimetabolites, Antineoplastic; Apoptosis; Aziridines; Blotting, Western; Caspases; Drug Synergism; Enzyme Inhibitors; Female; Flow Cytometry; Fluorouracil; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Nitroreductases; Ovarian Neoplasms; Prodrugs; Tumor Cells, Cultured

2003
Generation of Escherichia coli nitroreductase mutants conferring improved cell sensitization to the prodrug CB1954.
    Cancer research, 2003, Sep-01, Volume: 63, Issue:17

    Topics: Adenoviridae; Antineoplastic Agents; Aziridines; Escherichia coli; Female; Genetic Vectors; Humans; Mutagenesis, Site-Directed; Nitroreductases; Ovarian Neoplasms; Prodrugs; Tumor Cells, Cultured

2003
Methods to improve efficacy in suicide gene therapy approaches: targeting prodrug-activating enzymes carboxypeptidase G2 and nitroreductase to different subcellular compartments.
    Methods in molecular medicine, 2004, Volume: 90

    Topics: Antineoplastic Agents; Aziridines; Bystander Effect; Cell Survival; Female; gamma-Glutamyl Hydrolase; Genes, Transgenic, Suicide; Genetic Therapy; Glutamates; Humans; Nitrogen Mustard Compounds; Nitroreductases; Ovarian Neoplasms; Prodrugs; Subcellular Fractions; Transfection; Tumor Cells, Cultured

2004
The nitroreductase/CB1954 enzyme-prodrug system.
    Methods in molecular medicine, 2004, Volume: 90

    Topics: 3T3 Cells; Adenoviridae; Animals; Antineoplastic Agents; Aziridines; Biotransformation; Cell Line; Cell Survival; Female; Genes, Transgenic, Suicide; Genetic Therapy; Humans; Kidney; Mice; Mice, Nude; Nitroreductases; Ovarian Neoplasms; Prodrugs; Tumor Cells, Cultured; Viral Plaque Assay

2004
Escherichia coli nitroreductase plus CB1954 enhances the effect of radiotherapy in vitro and in vivo.
    Gene therapy, 2008, Volume: 15, Issue:6

    Topics: Animals; Apoptosis; Aziridines; Cell Line, Tumor; Combined Modality Therapy; Cytomegalovirus; DNA Fragmentation; Escherichia coli; Female; Flow Cytometry; Genetic Therapy; Genetic Vectors; Mice; Mice, Nude; Neoplasm Transplantation; Nitroreductases; Ovarian Neoplasms; Radiation-Sensitizing Agents; Transduction, Genetic

2008
Sensitisation of human ovarian cancer cells to killing by the prodrug CB1954 following retroviral or adenoviral transfer of the E. coli nitroreductase gene.
    Advances in experimental medicine and biology, 1998, Volume: 451

    Topics: Adenoviridae; Antineoplastic Agents; Aziridines; Cell Division; Escherichia coli; Female; Genetic Therapy; Humans; Nitroreductases; Ovarian Neoplasms; Prodrugs; Recombinant Proteins; Retroviridae; Transfection; Tumor Cells, Cultured

1998
Virus directed enzyme prodrug therapy for ovarian and pancreatic cancer using retrovirally delivered E. coli nitroreductase and CB1954.
    Gene therapy, 1998, Volume: 5, Issue:8

    Topics: Animals; Antineoplastic Agents; Aziridines; Female; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Mice; Mice, Inbred BALB C; Nitroreductases; Ovarian Neoplasms; Pancreatic Neoplasms; Prodrugs; Retroviridae

1998