Page last updated: 2024-08-26

tretazicar and Neoplasms

tretazicar has been researched along with Neoplasms in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.33)	18.7374
1990's	7 (23.33)	18.2507
2000's	17 (56.67)	29.6817
2010's	4 (13.33)	24.3611
2020's	1 (3.33)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Anderson, JLR; Christofferson, AJ; Day, MA; Evans, A; Hyde, EI; Searle, PF; Vass, SO; White, SA	1
Jeavons, M; Lehouritis, P; McCarthy, FO; Stanton, M; Tangney, M	1
Agarwal, R; Ali, R; Anderson, D; Auton, T; Cattell, E; Davies, S; Hartley, JA; Judson, I; Kerr, DJ; Knox, R; Middleton, MR; Midgley, R; Oppermann, U; Osawa, T; Sarker, D; Spanswick, VJ	1
Bhaumik, S; Depuy, J; Klimash, J; Paulmurugan, R; Sekar, TV	1
Gwenin, CD; Gwenin, VV; Kalaji, M	1
Anderson, CJ; Bilsland, AE; Evans, TR; Fletcher-Monaghan, AJ; Ganly, I; Keith, WN; Knox, RJ; McGregor, F; Plumb, JA	1
Ferry, DM; Helsby, NA; Patterson, AV; Pullen, SM; Wilson, WR	1
Minton, NP	1
Sausville, EA	1
Chen, MJ; Grove, JI; Guise, C; Hu, L; Hyde, EI; Jaberipour, M; James, ND; Kerr, DJ; Lovering, AL; Mautner, V; Mountain, A; Race, PR; Searle, PF; White, SA; Young, LS	1
Chen, MJ; Kerr, DJ; Palmer, DH; Searle, PF; Young, LS	1
Ackerley, DF; Barak, Y; Contag, CH; Lynch, SV; Matin, A; Thorne, SH	1
Boyle, RG; Travers, S	1
Berne, C; Betancor, L; Luckarift, HR; Spain, JC	1
Grove, JI; Guise, CP; Hyde, EI; Searle, PF	1
Bai, SY; Denny, WA; Li, D; Patterson, AV; Shen, Y; Singleton, DC; Smaill, JB; Syddall, SP; Wilson, WR	1
Adams, GE	1
Brehm, JK; Brown, JM; Fox, M; Giaccia, A; Lemmon, MJ; Mauchline, ML; Michael, NP; Minton, NP	1
Bailey, SM; Burke, PJ; Connors, TA; Hart, IR; Hobbs, SM; Jenkins, TC; Knox, RJ; Mauger, AB; Melton, RG	1
Brown, JM; Fox, ME; Giaccia, AJ; Lemmon, MJ; Mauchline, ML; Minton, NP; van Zijl, P	1
Court, S; Denny, WA; Ford, M; Friedlos, F; Springer, C	1
Clark, AJ; Cui, W; Gusterson, B	1
Bagshawe, KD; Burke, PJ; Knox, RJ; Melton, RG; Sharma, SK	1
Argyle, DJ; Blackwood, L; O'Shaughnessy, PJ; Reid, SW	1
Bilsland, A; Evans, TR; Glasspool, RM; Kakani, R; Keith, WN; Knox, RJ; Plumb, JA; Zhao, J	1
Denny, WA; Helsby, NA; Hicks, KO; Hogg, A; Pullen, SM; Wilson, WR	1
Brunicardi, FC; Fisher, WE; Yazawa, K	1
Denny, WA	1
Riley, RJ; Workman, P	1

Reviews

8 review(s) available for tretazicar and Neoplasms

Article	Year
Clostridia in cancer therapy. Nature reviews. Microbiology, 2003, Volume: 1, Issue:3 Topics: Animals; Antineoplastic Agents; Aziridines; Carcinoma; Clostridium; Cytosine Deaminase; Drug Delivery Systems; Humans; Mice; Neoplasms; Nitroreductases; Prodrugs; Spores, Bacterial; Xanthones	2003
Nitroreductase: a prodrug-activating enzyme for cancer gene therapy. Clinical and experimental pharmacology & physiology, 2004, Volume: 31, Issue:11 Topics: Animals; Antineoplastic Agents; Aziridines; Biotransformation; Clinical Trials as Topic; Combined Modality Therapy; Genetic Engineering; Genetic Therapy; Humans; Neoplasms; Nitroreductases; Prodrugs	2004
Hypoxia: targeting the tumour. Anti-cancer agents in medicinal chemistry, 2006, Volume: 6, Issue:4 Topics: Anthraquinones; Antineoplastic Agents; Aziridines; Benzoquinones; Cell Hypoxia; Clinical Trials, Phase III as Topic; Drug Screening Assays, Antitumor; Humans; Imidazoles; Indolequinones; Neoplasms; Prodrugs; Quinolines; Radiation-Sensitizing Agents; Tirapazamine; Triazines	2006
Chemotherapeutic tumour targeting using clostridial spores. FEMS microbiology reviews, 1995, Volume: 17, Issue:3 Topics: Animals; Antineoplastic Agents; Aziridines; Biotransformation; Clostridium; DNA, Recombinant; Drug Delivery Systems; Mice; Neoplasms; Nitroreductases; Prodrugs; Spores, Bacterial	1995
Developments with targeted enzymes in cancer therapy. Current opinion in immunology, 1999, Volume: 11, Issue:5 Topics: Antineoplastic Agents; Aziridines; Drug Carriers; Enzyme Therapy; gamma-Glutamyl Hydrolase; Humans; Immunoconjugates; Neoplasms; Polyethylene Glycols; Prodrugs	1999
Current progress in suicide gene therapy for cancer. World journal of surgery, 2002, Volume: 26, Issue:7 Topics: Animals; Antiviral Agents; Arabinonucleosides; Aziridines; Clinical Trials as Topic; Cytosine Deaminase; Escherichia coli; Flucytosine; Ganciclovir; Genetic Therapy; Genetic Vectors; Herpesvirus 3, Human; Humans; Neoplasms; Nitroreductases; Nucleoside Deaminases; Pentosyltransferases; Prodrugs; Purine Nucleosides; Simplexvirus; Thymidine Kinase; Xanthines	2002
Nitroreductase-based GDEPT. Current pharmaceutical design, 2002, Volume: 8, Issue:15 Topics: Animals; Antineoplastic Agents; Aziridines; Cell Survival; Drug Design; Genetic Therapy; Humans; Mice; Neoplasms; Nitroreductases; Prodrugs; Substrate Specificity; Tumor Cells, Cultured	2002
DT-diaphorase and cancer chemotherapy. Biochemical pharmacology, 1992, Apr-15, Volume: 43, Issue:8 Topics: Animals; Antineoplastic Agents; Aziridines; Benzoquinones; Dihydrolipoamide Dehydrogenase; Drug Design; Enzyme Induction; Gene Expression Regulation, Enzymologic; Humans; Indolequinones; Indoles; Mitomycin; Neoplasms; Precancerous Conditions; Tirapazamine; Triazines	1992

Trials

1 trial(s) available for tretazicar and Neoplasms

Article	Year
Quinone oxidoreductase-2-mediated prodrug cancer therapy. Science translational medicine, 2010, Jul-14, Volume: 2, Issue:40 Topics: Adult; Aged; Antineoplastic Agents; Aziridines; Cell Death; Cross-Linking Reagents; Crystallography, X-Ray; DNA, Neoplasm; Enzyme Activation; Female; Humans; Male; Middle Aged; Models, Molecular; Neoplasms; Prodrugs; Quinone Reductases	2010

Other Studies

21 other study(ies) available for tretazicar and Neoplasms

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Structure and Dynamics of Three International journal of molecular sciences, 2023, Mar-22, Volume: 24, Issue:6 Topics: Escherichia coli; Escherichia coli Proteins; Humans; NAD; Neoplasms; Nitroreductases; Oxidoreductases; Prodrugs	2023
Activation of multiple chemotherapeutic prodrugs by the natural enzymolome of tumour-localised probiotic bacteria. Journal of controlled release : official journal of the Controlled Release Society, 2016, Jan-28, Volume: 222 Topics: Animals; Anthraquinones; Antineoplastic Agents; Aziridines; Bacterial Proteins; Bifidobacterium; Cell Line, Tumor; Drug Delivery Systems; Enzymes; Escherichia coli; Female; Lactobacillus; Lactococcus; Mice, Inbred BALB C; Neoplasms; Probiotics; Prodrugs; Tumor Burden; Vidarabine Phosphate	2016
Noninvasive optical imaging of nitroreductase gene-directed enzyme prodrug therapy system in living animals. Gene therapy, 2012, Volume: 19, Issue:3 Topics: Animals; Aziridines; Cell Line; Enzyme Activation; Gene Expression; Gene Order; Genetic Vectors; Humans; Intestinal Mucosa; Intestines; Kinetics; Metagenome; Mice; Mice, Nude; Molecular Imaging; Neoplasms; Nitroreductases; Prodrugs; Transfection; Transplantation, Heterologous	2012
Colloidal gold modified with a genetically engineered nitroreductase: toward a novel enzyme delivery system for cancer prodrug therapy. Langmuir : the ACS journal of surfaces and colloids, 2011, Dec-06, Volume: 27, Issue:23 Topics: Aziridines; Colloids; Drug Delivery Systems; Gold; Humans; Models, Molecular; Neoplasms; Nitroreductases; Prodrugs; Protein Engineering; Recombinant Proteins; Sodium Chloride	2011
Selective ablation of human cancer cells by telomerase-specific adenoviral suicide gene therapy vectors expressing bacterial nitroreductase. Oncogene, 2003, Jan-23, Volume: 22, Issue:3 Topics: Adenocarcinoma; Adenoviridae; Animals; Antineoplastic Agents; Aziridines; Bacterial Proteins; Base Sequence; DNA-Binding Proteins; Drug Resistance, Neoplasm; Female; Genetic Therapy; Genetic Vectors; Humans; Male; Mice; Mice, Nude; Molecular Sequence Data; Neoplasms; Nitroreductases; Ovarian Neoplasms; Promoter Regions, Genetic; Telomerase; Tumor Cells, Cultured; Uterine Cervical Neoplasms	2003
2-Amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPT. British journal of cancer, 2004, Mar-08, Volume: 90, Issue:5 Topics: Aniline Mustard; Antineoplastic Agents; Aziridines; Bystander Effect; Chromatography, High Pressure Liquid; Escherichia coli; Genetic Therapy; Genetic Vectors; Humans; Mass Spectrometry; Neoplasms; Nitroreductases; Prodrugs; Structure-Activity Relationship; Tumor Cells, Cultured	2004
Genes in the service of therapeutic index: progress for virus-directed enzyme prodrug therapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, May-01, Volume: 22, Issue:9 Topics: Aziridines; Clinical Trials as Topic; DNA Adducts; Escherichia coli; Genetic Engineering; Genetic Therapy; Humans; Neoplasms; Nitroreductases; Prodrugs; RNA Viruses	2004
Inhibition of NF-kappaB enhances the cytotoxicity of virus-directed enzyme prodrug therapy and oncolytic adenovirus cancer gene therapy. Gene therapy, 2005, Volume: 12, Issue:15 Topics: Adenoviridae; Aziridines; Cell Line, Tumor; Enzyme Activation; Genetic Therapy; Genetic Vectors; Humans; Neoplasms; NF-kappa B; Nitroreductases; Oncolytic Virotherapy; Oncolytic Viruses; Prodrugs; Signal Transduction; Virus Replication	2005
New enzyme for reductive cancer chemotherapy, YieF, and its improvement by directed evolution. Molecular cancer therapeutics, 2006, Volume: 5, Issue:1 Topics: Antineoplastic Agents; Aziridines; Drug Delivery Systems; Escherichia coli Proteins; Evolution, Molecular; HeLa Cells; Humans; Mitomycin; Neoplasms; Oxidoreductases; Prodrugs; Salmonella typhimurium; Sequence Analysis, Protein	2006
Application of a microfluidic reactor for screening cancer prodrug activation using silica-immobilized nitrobenzene nitroreductase. Biomacromolecules, 2006, Volume: 7, Issue:9 Topics: Antineoplastic Agents; Aziridines; Biotechnology; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Enzymes, Immobilized; Humans; Neoplasms; Nitrobenzenes; Nitroreductases; Polyethyleneimine; Prodrugs; Pseudomonas; Silicon Dioxide; Substrate Specificity	2006
Direct positive selection for improved nitroreductase variants using SOS triggering of bacteriophage lambda lytic cycle. Gene therapy, 2007, Volume: 14, Issue:8 Topics: Aziridines; Bacteriophage lambda; Cell Line, Tumor; Escherichia coli; Escherichia coli Proteins; Genetic Therapy; Humans; Neoplasms; Nitroreductases; Prodrugs; SOS Response, Genetics	2007
The nitroreductase prodrug SN 28343 enhances the potency of systemically administered armed oncolytic adenovirus ONYX-411(NTR). Cancer gene therapy, 2007, Volume: 14, Issue:12 Topics: Adenoviridae; Animals; Antineoplastic Agents; Aziridines; Escherichia coli Proteins; Gene Expression; Humans; Mice; Mice, Mutant Strains; Neoplasms; Nitrogen Mustard Compounds; Nitroreductases; Oncolytic Virotherapy; Oncolytic Viruses; Prodrugs; Time Factors; Transduction, Genetic; Virus Replication; Xenograft Model Antitumor Assays	2007
Radiosensitizers: a conference preview. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Animals; Aziridines; Buthionine Sulfoximine; Carmustine; Combined Modality Therapy; Drug Synergism; Etanidazole; Humans; Ketones; Lomustine; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1984
Investigation of alternative prodrugs for use with E. coli nitroreductase in 'suicide gene' approaches to cancer therapy. Gene therapy, 1996, Volume: 3, Issue:12 Topics: Animals; Antineoplastic Agents; Aziridines; Biotransformation; Catalysis; Cell Line; Cricetinae; Cricetulus; Escherichia coli; Genetic Therapy; Neoplasms; Nitroreductases; Prodrugs; Transfection	1996
Anaerobic bacteria as a gene delivery system that is controlled by the tumor microenvironment. Gene therapy, 1997, Volume: 4, Issue:8 Topics: Animals; Antineoplastic Agents; Aziridines; Clostridium; Escherichia coli; Female; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Mice; Mice, Inbred BALB C; Neoplasms; Nitroreductases; Prodrugs	1997
Gene-directed enzyme prodrug therapy: quantitative bystander cytotoxicity and DNA damage induced by CB1954 in cells expressing bacterial nitroreductase. Gene therapy, 1998, Volume: 5, Issue:1 Topics: Aziridines; DNA Damage; Escherichia coli; Gene Expression; Genetic Therapy; Humans; Neoplasms; Nitroreductases; Prodrugs; Transfection; Tumor Cells, Cultured	1998
Nitroreductase-mediated cell ablation is very rapid and mediated by a p53-independent apoptotic pathway. Gene therapy, 1999, Volume: 6, Issue:5 Topics: Animals; Antineoplastic Agents; Apoptosis; Aziridines; Female; Genes, p53; Genetic Therapy; Immunohistochemistry; In Situ Nick-End Labeling; Mammary Glands, Animal; Mice; Mice, Transgenic; Neoplasms; Nitroreductases; Prodrugs; Time Factors	1999
E. coli nitroreductase/CB1954: in vitro studies into a potential system for feline cancer gene therapy. Veterinary journal (London, England : 1997), 2001, Volume: 161, Issue:3 Topics: Animals; Antineoplastic Agents; Aziridines; Base Sequence; Blotting, Western; Cat Diseases; Cats; Cytotoxicity Tests, Immunologic; DNA Primers; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genetic Therapy; Molecular Sequence Data; Neoplasms; Nitroreductases; Polymerase Chain Reaction; Prodrugs; Rats; Transfection; Tumor Cells, Cultured	2001
Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954. Oncogene, 2001, Nov-22, Volume: 20, Issue:53 Topics: Animals; Aziridines; Bacteria; Carcinoma, Small Cell; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Female; Gene Expression Regulation, Enzymologic; Genetic Therapy; Genetic Vectors; Humans; Mice; Neoplasm Transplantation; Neoplasms; Nitroreductases; Prodrugs; Promoter Regions, Genetic; Telomerase; Transgenes; Transplantation, Heterologous; Tumor Cells, Cultured; Uterine Cervical Neoplasms	2001
Quantitation of bystander effects in nitroreductase suicide gene therapy using three-dimensional cell cultures. Cancer research, 2002, Mar-01, Volume: 62, Issue:5 Topics: Aniline Mustard; Animals; Aziridines; Bystander Effect; Cell Culture Techniques; Cricetinae; Genetic Therapy; Humans; Neoplasms; Nitroreductases; Prodrugs; Structure-Activity Relationship; Tumor Cells, Cultured	2002