Page last updated: 2024-08-26

tretazicar and Experimental Neoplasms

tretazicar has been researched along with Experimental Neoplasms in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's1 (9.09)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Chang, D; Chang, HF; Chen, BM; Chen, SH; Chen, TC; Collins, S; Kasahara, N; Lin, SC; Lu, YC; Sun, JM; Tai, CK; Wang, HE; Wang, W; Wu, SF1
Ackerley, DF; Chan-Hyams, JV; Copp, JN; Little, RF; Mowday, AM; Patterson, AV; Rich, MH; Smaill, JB; Williams, EM1
Braidwood, L; Brown, SM; Dunn, PD; Evans, TR; Hardy, S1
Walton, MI; Workman, P1
Bailey, SM; Hart, IR1
Dexter, MT; Djeha, AH; Hulme, A; Kerr, DJ; Mountain, A; Searle, PF; Wrighton, CJ; Young, LS1
Kestell, P; Palmer, BD; Pruijn, FB; Siim, BG; Wilson, WR1
Boland, MP; Friedlos, F; Knox, RJ; Kotsaki-Kovatsi, VP; Marchbank, T; Roberts, JJ1
Chaplin, DJ1
Talbot, K; White, RA; Workman, P1
Donaldson, J; Morgan, JE; Talbot, K; Twentyman, PR; Workman, P; Wright, KA1

Reviews

1 review(s) available for tretazicar and Experimental Neoplasms

ArticleYear
Nitroreductase gene-directed enzyme prodrug therapy: insights and advances toward clinical utility.
    The Biochemical journal, 2015, Oct-15, Volume: 471, Issue:2

    Topics: Animals; Aziridines; Directed Molecular Evolution; Escherichia coli Proteins; Genetic Therapy; Humans; Neoplasms, Experimental; Nitroreductases; Prodrugs

2015

Other Studies

10 other study(ies) available for tretazicar and Experimental Neoplasms

ArticleYear
Efficient Prodrug Activator Gene Therapy by Retroviral Replicating Vectors Prolongs Survival in an Immune-Competent Intracerebral Glioma Model.
    International journal of molecular sciences, 2020, Feb-20, Volume: 21, Issue:4

    Topics: Animals; Aziridines; Brain Neoplasms; Cell Line, Tumor; Cytosine Deaminase; Escherichia coli Proteins; Flucytosine; Genetic Therapy; Genetic Vectors; Glioma; Leukemia Virus, Gibbon Ape; Neoplasms, Experimental; Nitroreductases; Prodrugs; Rats, Inbred F344; Saccharomyces cerevisiae Proteins

2020
Antitumor activity of a selectively replication competent herpes simplex virus (HSV) with enzyme prodrug therapy.
    Anticancer research, 2009, Volume: 29, Issue:6

    Topics: Animals; Antineoplastic Agents; Aziridines; Blotting, Western; Combined Modality Therapy; Female; Herpes Simplex; Herpesvirus 1, Human; Humans; Immunoenzyme Techniques; Mice; Mice, Nude; Neoplasms, Experimental; Oncolytic Viruses; Polymerase Chain Reaction; Prodrugs; Tissue Distribution; Virus Replication

2009
Pharmacology of the mixed-function radio- and chemosensitizers CB 1954 and RSU 1069.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8

    Topics: Animals; Aziridines; Azirines; Brain; Drug Synergism; Female; Male; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Radiation-Sensitizing Agents; Time Factors

1984
Nitroreductase activation of CB1954--an alternative 'suicide' gene system.
    Gene therapy, 1997, Volume: 4, Issue:2

    Topics: Animals; Antineoplastic Agents; Aziridines; Genetic Therapy; Mice; Neoplasms, Experimental; Nitroreductases; Prodrugs; Tumor Cells, Cultured

1997
Expression of Escherichia coli B nitroreductase in established human tumor xenografts in mice results in potent antitumoral and bystander effects upon systemic administration of the prodrug CB1954.
    Cancer gene therapy, 2000, Volume: 7, Issue:5

    Topics: Animals; Apoptosis; Aziridines; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Cross-Linking Reagents; Dose-Response Relationship, Drug; Escherichia coli; Head and Neck Neoplasms; Humans; Immunohistochemistry; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Necrosis; Neoplasm Transplantation; Neoplasms, Experimental; Nitroreductases; Prodrugs; Remission Induction; Time Factors; Tumor Cells, Cultured

2000
Pharmacokinetics and metabolism of the nitrogen mustard bioreductive drug 5.
    Cancer chemotherapy and pharmacology, 2000, Volume: 46, Issue:5

    Topics: Aniline Mustard; Animals; Antineoplastic Agents; Aziridines; Biotransformation; Chromatography, High Pressure Liquid; Injections, Intravenous; Injections, Subcutaneous; Male; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Prodrugs

2000
Caffeine, aminoimidazolecarboxamide and dicoumarol, inhibitors of NAD(P)H dehydrogenase (quinone) (DT diaphorase), prevent both the cytotoxicity and DNA interstrand crosslinking produced by 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) in Walker cells.
    Biochemical pharmacology, 1989, Nov-15, Volume: 38, Issue:22

    Topics: Aminoimidazole Carboxamide; Animals; Antineoplastic Agents; Aziridines; Caffeine; Cross-Linking Reagents; Dicumarol; DNA; Drug Synergism; NAD(P)H Dehydrogenase (Quinone); Neoplasms, Experimental; Quinone Reductases; Rats; Tumor Cells, Cultured; Vitamin K

1989
Hydralazine-induced tumor hypoxia: a potential target for cancer chemotherapy.
    Journal of the National Cancer Institute, 1989, Apr-19, Volume: 81, Issue:8

    Topics: Animals; Antineoplastic Agents; Aziridines; Drug Synergism; Female; Hydralazine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Misonidazole; Mitomycins; Neoplasms, Experimental; Regional Blood Flow

1989
CB 1954 revisited. I. Disposition kinetics and metabolism.
    Cancer chemotherapy and pharmacology, 1986, Volume: 16, Issue:1

    Topics: Allopurinol; Animals; Aziridines; Azirines; Biotransformation; Brain; Dogs; Drug Interactions; Kinetics; Male; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phenobarbital

1986
CB 1954 revisited. II. Toxicity and antitumour activity.
    Cancer chemotherapy and pharmacology, 1986, Volume: 16, Issue:1

    Topics: Animals; Aziridines; Azirines; Colonic Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Interactions; Humans; Lomustine; Mammary Neoplasms, Experimental; Melphalan; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Sarcoma, Experimental

1986