Page last updated: 2024-08-26

tretazicar and Colorectal Cancer

tretazicar has been researched along with Colorectal Cancer in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Doshi, R; Green, NK; Kerr, DJ; McNeish, IA; Searle, PF; Young, LS1
Bonney, S; Ellis, J; Gerritsen, W; Harris, PA; Hill, S; Horne, M; Hubscher, S; Hull, D; James, ND; Kerr, DJ; Mautner, V; Mirza, D; Mountain, A; Oliff, S; Palmer, DH; Rajaratnam, R; Reynolds, G; Searle, PF; van der Sijp, JR; Young, LS1
Chen, MJ; Flavell, JR; Green, NK; Kerr, DJ; Mautner, V; Reynolds, GM; Searle, PF; Young, LS1
Anlezark, G; Anné, J; Burke, PJ; Dubois, L; Dûrre, P; Lambin, P; Landuyt, W; Mengesha, A; Minton, NP; Pennington, O; Theys, J; Vaughan, T; Wouters, BG1
Djeha, AH; Harris, PA; Kerr, DJ; Leung, H; Mountain, A; Searle, PF; Thomson, TA; Wrighton, CJ; Young, LS1
Chen, MJ; Chung-Faye, GA; Kerr, DJ; Searle, PF; Young, LS1
Djeha, AH; Ismail, T; Lipinski, KS; Mountain, A; Wrighton, CJ; Young, LS1

Reviews

1 review(s) available for tretazicar and Colorectal Cancer

ArticleYear
Gene therapy for colorectal cancer: therapeutic potential.
    BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 2001, Volume: 15, Issue:6

    Topics: Adenoviridae; Antigen Presentation; Aziridines; Carcinoembryonic Antigen; Clinical Trials as Topic; Colorectal Neoplasms; Flucytosine; Ganciclovir; Genes, p53; Genetic Therapy; Humans; T-Lymphocytes, Cytotoxic

2001

Trials

1 trial(s) available for tretazicar and Colorectal Cancer

ArticleYear
Virus-directed enzyme prodrug therapy: intratumoral administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, May-01, Volume: 22, Issue:9

    Topics: Adenoviridae; Aged; Aziridines; Carcinoma, Hepatocellular; Colorectal Neoplasms; DNA Adducts; Drug Resistance, Neoplasm; Escherichia coli Proteins; Female; Flavoproteins; Gene Expression Regulation; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Half-Life; Humans; Immunohistochemistry; Liver Neoplasms; Male; Middle Aged; Nitroreductases; Prodrugs; Transgenes; Virus Replication

2004

Other Studies

5 other study(ies) available for tretazicar and Colorectal Cancer

ArticleYear
Immune enhancement of nitroreductase-induced cytotoxicity: studies using a bicistronic adenovirus vector.
    International journal of cancer, 2003, Mar-10, Volume: 104, Issue:1

    Topics: Adenocarcinoma; Adenoviruses, Human; Adjuvants, Immunologic; Animals; Antineoplastic Agents, Alkylating; Aziridines; Bystander Effect; Colorectal Neoplasms; Combined Modality Therapy; Cytomegalovirus; Defective Viruses; Drug Resistance, Neoplasm; Escherichia coli Proteins; Female; Genes; Genes, Synthetic; Genetic Therapy; Genetic Vectors; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunotherapy; Mesothelioma; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Nitroreductases; Prodrugs; Specific Pathogen-Free Organisms; Tumor Cells, Cultured

2003
Enhanced efficacy of Escherichia coli nitroreductase/CB1954 prodrug activation gene therapy using an E1B-55K-deleted oncolytic adenovirus vector.
    Gene therapy, 2004, Volume: 11, Issue:14

    Topics: Adenoviridae; Adenovirus E2 Proteins; Animals; Aziridines; Cell Line, Tumor; Colorectal Neoplasms; Enzyme Activation; Escherichia coli; Genetic Therapy; Genetic Vectors; Humans; Mice; Mice, Nude; Nitroreductases; Prodrugs; Virus Replication

2004
Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo.
    British journal of cancer, 2006, Nov-06, Volume: 95, Issue:9

    Topics: Animals; Antineoplastic Agents; Aziridines; Cell Line; Cell Survival; Clostridium; Colorectal Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Genetic Therapy; Genetic Vectors; HCT116 Cells; Humans; Mice; Mice, Inbred Strains; Mice, Nude; Nitroreductases; Prodrugs; Recombinant Proteins; Spores, Bacterial; Treatment Outcome; Xenograft Model Antitumor Assays

2006
Combined adenovirus-mediated nitroreductase gene delivery and CB1954 treatment: a well-tolerated therapy for established solid tumors.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2001, Volume: 3, Issue:2

    Topics: Adenoviridae; Animals; Antineoplastic Agents; Aziridines; Carcinoma, Hepatocellular; Colorectal Neoplasms; Dose-Response Relationship, Drug; Escherichia coli; Gene Transfer Techniques; Genetic Therapy; Head and Neck Neoplasms; Humans; Liver Neoplasms; Luciferases; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nitroreductases; Prodrugs; Prostatic Neoplasms; Transduction, Genetic; Transfection; Tumor Cells, Cultured

2001
High-level, beta-catenin/TCF-dependent transgene expression in secondary colorectal cancer tissue.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2001, Volume: 4, Issue:4

    Topics: Adenoviridae; Animals; Antineoplastic Agents; Aziridines; beta Catenin; beta-Galactosidase; Biopsy; Colorectal Neoplasms; Cytoskeletal Proteins; Gene Expression Regulation, Neoplastic; Genes, Reporter; Genetic Therapy; Genetic Vectors; Humans; Liver; Mice; Nitroreductases; Organ Specificity; Prodrugs; Promoter Regions, Genetic; Trans-Activators; Transgenes; Tumor Cells, Cultured

2001