Page last updated: 2024-08-21

treosulfan and Malignant Melanoma

treosulfan has been researched along with Malignant Melanoma in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.52)18.2507
2000's17 (80.95)29.6817
2010's1 (4.76)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Garri, DD; Karamysheva, АF; Moiseeva, NI; Saakyan, SV; Tsygankov, АY1
Atzpodien, J; Fluck, M; Reitz, M; Terfloth, K3
Neuber, K1
Baumgart, J; Deutschmann, A; Hauschild, A; Mohr, P; Neuber, K; Pföhler, C; Pichlmeier, U; Reinhold, U1
Corrie, PG; Cree, IA; Haass, N; Hengge, U; Kuwert, C; Neuber, K; Pföhler, C; Reinhold, U; Tilgen, W; Ugurel, S; Zutt, M1
Gille, J; Kaufmann, R; Spieth, K1
Becker, JC; Bröcker, EB; Terheyden, P1
Bechrakis, N; Foerster, MH; Keilholz, U; Schmittel, A; Schuster, R; Siehl, J; Thiel, E1
Cree, IA; Di Nicolantonio, F; Glaysher, S; Johnson, P; Knight, LA; Mercer, S; Sharma, S; Whitehouse, P1
Cree, IA; Kurbacher, CM; Neale, MH; Reinhold, U1
Bulusu, R; Corrie, PG; Cree, IA; Hartley, JA; Jonson, A; Mayer, A; Sehmbi, R; Shaw, J; Spanswick, VJ1
Baumgart, J; Bechrakis, NE; Bornfeld, N; Foerster, MH; Keilholz, U; Scheulen, ME; Schmittel, A; Strumberg, D; Thiel, E1
Bechrakis, NE; Foerster, MH; Keilholz, U; Schmittel, A; Schuster, R; Siehl, JM; Thiel, E1
Mauch, C1
Butt, M; Eswar, CV; Gillis, P; Marshall, E; O'Neill, PA1
Bechrakis, NE; Foerster, MH; Keilholz, U; Martus, P; Schmidt-Hieber, M; Schmittel, A; Schuster, R; Siehl, JM; Thiel, E1
Delorme, S; Hauschild, A; Kaatz, M; Neuber, K; Pföhler, C; Reinhold, U; Rittgen, W; Schadendorf, D; Spieth, K; Thoelke, A; Tilgen, W; Ugurel, S; Ulrich, J1
Cree, IA; Foss, AJ; Hungerford, JL; Kurbacher, CM; Myatt, N; Neale, MH; Plowman, PN1
Blödorn-Schlicht, N; Itschert, G; Karnbach, C; Neuber, K; tom Dieck, A1

Trials

14 trial(s) available for treosulfan and Malignant Melanoma

ArticleYear
Treosulfan in the treatment of metastatic melanoma: from chemosensitivity testing to clinical trials.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2003, Volume: 161

    Topics: Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Busulfan; Disease Progression; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Luminescent Measurements; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Neoplasm Staging; Skin Neoplasms; Survival Rate; Tumor Cells, Cultured

2003
Second-line chemotherapy of metastatic malignant melanoma with intravenous treosulfan: a phase II multicentre trial.
    Melanoma research, 2003, Volume: 13, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Busulfan; Disease Progression; Female; Humans; Infusions, Intravenous; Male; Melanoma; Middle Aged; Neoplasm Staging; Salvage Therapy; Skin Neoplasms; Survival Rate; Time Factors; Treatment Outcome

2003
Treosulfan and gemcitabine in metastatic uveal melanoma patients: results of a multicenter feasibility study.
    Anti-cancer drugs, 2003, Volume: 14, Issue:5

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Deoxycytidine; Disease Progression; Feasibility Studies; Female; Gemcitabine; Hematologic Diseases; Humans; Male; Melanoma; Middle Aged; Pilot Projects; Survival Analysis; Uveal Neoplasms

2003
Metronomic oral low-dose treosulfan chemotherapy combined with cyclooxygenase-2 inhibitor in pretreated advanced melanoma: a pilot study.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Apoptosis; Busulfan; Cell Division; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Progression; Drug Therapy, Combination; Endothelial Cells; Female; Humans; Isoenzymes; Lactones; Male; Melanoma; Membrane Proteins; Middle Aged; Pilot Projects; Prostaglandin-Endoperoxide Synthases; Sulfones

2003
Clinical evaluation of in vitro chemosensitivity testing: the example of uveal melanoma.
    Journal of cancer research and clinical oncology, 2004, Volume: 130, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Choroid Neoplasms; Deoxycytidine; Drug Administration Schedule; Female; Gemcitabine; Humans; Karnofsky Performance Status; Male; Melanoma; Middle Aged; Neoplasm Staging; Survival Analysis; Treatment Failure; Treatment Outcome; Uveal Neoplasms

2004
A clinical phase I trial of gemcitabine and treosulfan in uveal melanoma and other solid tumours.
    European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:14

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Deoxycytidine; Female; Gemcitabine; Humans; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Treatment Outcome; Uveal Neoplasms

2004
Phase I trial combining gemcitabine and treosulfan in advanced cutaneous and uveal melanoma patients.
    British journal of cancer, 2005, Jun-06, Volume: 92, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Comet Assay; Deoxycytidine; DNA Damage; Dose-Response Relationship, Drug; Female; Gemcitabine; Humans; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Skin Neoplasms; Uveal Neoplasms

2005
Phase II trial of cisplatin, gemcitabine and treosulfan in patients with metastatic uveal melanoma.
    Melanoma research, 2005, Volume: 15, Issue:3

    Topics: Adult; Aged; Anemia; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cisplatin; Deoxycytidine; Disease Progression; Female; Gemcitabine; Humans; Leukopenia; Male; Melanoma; Middle Aged; Survival Analysis; Thrombocytopenia; Uveal Neoplasms

2005
A two-cohort phase II clinical trial of gemcitabine plus treosulfan in patients with metastatic uveal melanoma.
    Melanoma research, 2005, Volume: 15, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cohort Studies; Deoxycytidine; Female; Gemcitabine; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Survival Analysis; Treatment Outcome; Uveal Neoplasms

2005
A prospective single arm phase II study of dacarbazine and treosulfan as first-line therapy in metastatic uveal melanoma.
    Melanoma research, 2006, Volume: 16, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Prospective Studies; Thrombocytopenia; Uveal Neoplasms

2006
A randomized phase II trial of gemcitabine plus treosulfan versus treosulfan alone in patients with metastatic uveal melanoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Deoxycytidine; Female; Gemcitabine; Humans; Male; Melanoma; Middle Aged; Survival Analysis; Uveal Neoplasms

2006
In vitro drug sensitivity predicts response and survival after individualized sensitivity-directed chemotherapy in metastatic melanoma: a multicenter phase II trial of the Dermatologic Cooperative Oncology Group.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Sep-15, Volume: 12, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cisplatin; Deoxycytidine; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Gemcitabine; Humans; Male; Melanoma; Middle Aged; Paclitaxel; Skin Neoplasms; Survival Analysis; Treatment Outcome

2006
Cisplatin, gemcitabine, and treosulfan in relapsed stage IV cutaneous malignant melanoma patients.
    British journal of cancer, 2007, Nov-19, Volume: 97, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cisplatin; Deoxycytidine; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Gemcitabine; Humans; Injections, Intravenous; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Neoplasm Staging; Neoplasms, Unknown Primary; Recurrence; Remission Induction; Skin Neoplasms; Survival Rate; Treatment Outcome

2007
Treosulfan is an effective alkylating cytostatic for malignant melanoma in vitro and in vivo.
    Melanoma research, 1999, Volume: 9, Issue:2

    Topics: Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Busulfan; Dose-Response Relationship, Drug; Female; Humans; Male; Melanoma; Middle Aged; Pilot Projects; Tumor Cells, Cultured

1999

Other Studies

7 other study(ies) available for treosulfan and Malignant Melanoma

ArticleYear
Assessment of the Chemosensitivity of Uveal Melanoma Cells Ex Vivo.
    Bulletin of experimental biology and medicine, 2020, Volume: 170, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Benzeneacetamides; Busulfan; Cell Proliferation; Cell Survival; Choroid Neoplasms; Deoxycytidine; Diterpenes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Gemcitabine; Humans; Male; Melanoma; Middle Aged; Phenylacetates; Primary Cell Culture; Retinyl Esters; Tumor Cells, Cultured; Uveal Neoplasms; Valproic Acid

2020
Age has no significant impact on overall survival and on treatment tolerability in relapsed stage IV cutaneous malignant melanoma patients receiving Cisplatin, Gemcitabine, and Treosulfan.
    American journal of clinical oncology, 2011, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cisplatin; Deoxycytidine; Disease Progression; Female; Gemcitabine; Humans; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Neoplasm Staging; Remission Induction; Skin Neoplasms; Survival Rate; Treatment Outcome; Young Adult

2011
The in vitro effect of gefitinib ('Iressa') alone and in combination with cytotoxic chemotherapy on human solid tumours.
    BMC cancer, 2004, Nov-23, Volume: 4

    Topics: Adenocarcinoma; Adenosine Triphosphate; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Busulfan; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cisplatin; Colorectal Neoplasms; Deoxycytidine; Drug Screening Assays, Antitumor; Female; Gefitinib; Gemcitabine; Humans; Melanoma; Neoplasms; Neoplasms, Unknown Primary; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Quinazolines; Sarcoma; Skin Neoplasms; Stomach Neoplasms; Uveal Neoplasms

2004
Treosulfan and gemcitabine.
    Journal of cancer research and clinical oncology, 2005, Volume: 131, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Deoxycytidine; Gemcitabine; Humans; Melanoma; Reproducibility of Results; Uveal Neoplasms

2005
[Metronomic chemotherapy. Should we change our thinking in the treatment of advanced tumors?].
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2005, Volume: 3, Issue:1

    Topics: Administration, Oral; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Bevacizumab; Breast Neoplasms; Busulfan; Cyclooxygenase 2 Inhibitors; Cyclophosphamide; Drug Therapy, Combination; Female; Forecasting; Humans; Male; Melanoma; Neoplasm Metastasis; Neoplasms; Prospective Studies; Quality of Life; Skin Neoplasms; Time Factors; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A

2005
Cisplatin, gemcitabine and treosulfan is effective in chemotherapy-pretreated relapsed stage IV uveal melanoma patients.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cisplatin; Deoxycytidine; Female; Gemcitabine; Germany; Humans; Male; Melanoma; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Survival Rate; Uveal Neoplasms

2008
Combination chemotherapy for choroidal melanoma: ex vivo sensitivity to treosulfan with gemcitabine or cytosine arabinoside.
    British journal of cancer, 1999, Volume: 79, Issue:9-10

    Topics: Adenosine Triphosphate; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Choroid Neoplasms; Cytarabine; Deoxycytidine; Gemcitabine; Humans; Melanoma; Paclitaxel; Tumor Stem Cell Assay

1999