tremorine has been researched along with Parkinson Disease in 17 studies
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The anti-tremor potency of the compounds was assessed from suppression of Tremorine-induced tremors in mice." | 7.64 | Relationship between anti-acetylcholine and anti-Tremorine activity in anti-parkinsonian and related drugs. ( AHMED, A; MARSHALL, PB, 1962) |
| " The anti-tremor potency of the compounds was assessed from suppression of Tremorine-induced tremors in mice." | 3.64 | Relationship between anti-acetylcholine and anti-Tremorine activity in anti-parkinsonian and related drugs. ( AHMED, A; MARSHALL, PB, 1962) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| EVERETT, GM | 1 |
| BLOCKUS, LE | 1 |
| SHEPPERD, IM | 1 |
| TRAUTNER, EM | 1 |
| GERSHON, S | 1 |
| AHMED, A | 1 |
| MARSHALL, PB | 1 |
| PEPEU, G | 1 |
| Friedman, AH | 1 |
| Anton, AH | 1 |
| Curzon, G | 1 |
| Jacobi, H | 1 |
| Jurna, I | 1 |
| Nell, T | 1 |
| Schreyer, I | 1 |
| Patni, SK | 1 |
| Dandiya, PC | 2 |
| Morrison, AB | 1 |
| Webster, RA | 1 |
| Tasker, RR | 1 |
| Sogabe, K | 1 |
| Leonard, BE | 1 |
| Ban, T | 1 |
| Hojo, M | 1 |
| Brumlik, J | 2 |
| Means, ED | 2 |
| Bhargava, LP | 1 |
| Brown, DM | 1 |
| Hughes, BO | 1 |
| Mehta, MD | 1 |
1 review available for tremorine and Parkinson Disease
| Article | Year |
|---|---|
The biochemistry of dyskinesias.
Topics: Acetylcholine; Animals; Catecholamines; Cats; Copper; Dihydroxyphenylalanine; Dogs; Hepatolenticular | 1967 |
16 other studies available for tremorine and Parkinson Disease
| Article | Year |
|---|---|
Tremor induced by tremorine and its antagonism by anti-Parkinson drugs.
Topics: Antiparkinson Agents; Humans; Parkinson Disease; Pyrroles; Tremor; Tremorine | 1956 |
Use of tremorine for screening anti-parkinsonian drugs.
Topics: Drug Evaluation, Preclinical; Heterocyclic Compounds; Humans; Mass Screening; Parkinson Disease; Tre | 1959 |
Relationship between anti-acetylcholine and anti-Tremorine activity in anti-parkinsonian and related drugs.
Topics: Acetylcholine; Animals; Antiparkinson Agents; Antipsychotic Agents; Chlorpromazine; Cholinergic Anta | 1962 |
EFFECT OF 'TREMORINE' AND SOME ANTI-PARKINSON'S DISEASE DRUGS ON ACETYLCHOLINE IN THE RAT'S BRAIN.
Topics: Acetylcholine; Atropine; Brain; Heterocyclic Compounds; Parasympatholytics; Parkinson Disease; Pharm | 1963 |
The effect of tremorine on dopamine concentration in the brain of the rat, guinea pig and rabbit.
Topics: Animals; Brain; Brain Stem; Caudate Nucleus; Cerebellum; Dopamine; Extrapyramidal Tracts; Guinea Pig | 1967 |
[Inhibition of tremor by active beta-adrenolytic substances].
Topics: Animals; Depression, Chemical; Isoproterenol; Mice; Parkinson Disease; Propranolol; Sensory Receptor | 1967 |
Motor disturbance induced by tremorine and oxotremorine.
Topics: Acetylcholine; Amines; Animals; Atropine; Biperiden; Brain; Bridged-Ring Compounds; Chlorpromazine; | 1970 |
The influence of monoamine oxidase inhibitors and some other antidepressants on the anti-parkinsonian activity of sub-effective doses of diphenylhydramine in rats and mice.
Topics: Animals; Antidepressive Agents; Catatonia; Diphenhydramine; Humans; Mice; Monoamine Oxidase Inhibito | 1972 |
Drug-induced experimental Parkinsonism.
Topics: Animals; Atropine; Benztropine; Butyrophenones; Cats; Chlorpromazine; Dose-Response Relationship, Dr | 1973 |
A rat model for Parkinsonian rest tremor.
Topics: Animals; Cerebellum; Disease Models, Animal; Monoamine Oxidase Inhibitors; Parkinson Disease; Parkin | 1973 |
Anti-tremorine effects of some mono- and diacyloxytropanes.
Topics: Animals; Body Temperature; Butyrates; Drug Antagonism; Esters; Female; Germ-Free Life; Hypothermia; | 1972 |
A comparative study of the effects of anti-parkinson drugs on the oxotremorine-induced EEG and muscular activities.
Topics: Animals; Diphenhydramine; Drug Antagonism; Electroencephalography; Male; Muscle Tonus; Muscles; Orph | 1971 |
Tremorine tremor, shivering and human "shuddering" tremor: a comparative study.
Topics: Animals; Brain Stem; Encephalitis; Humans; Oscillometry; Parkinson Disease; Posture; Shivering; Trem | 1968 |
The antiparkinsonian activity of monoamine oxidase inhibitors and other agents in rats and mice.
Topics: Animals; Dextroamphetamine; Diphenhydramine; Imipramine; Iproniazid; Isocarboxazid; Mice; Monoamine | 1968 |
Tremorine-tremor, shivering and acute cerebellar ataxia in the adult and child--a comparative study.
Topics: Acute Disease; Adult; Animals; Body Temperature Regulation; Cerebellar Ataxia; Dogs; Eye Movements; | 1969 |
BRL 1288-a new anti-Parkinson drug.
Topics: Animals; Humans; Mice; Parasympatholytics; Parkinson Disease; Rats; Tremorine | 1969 |