trehalose has been researched along with Neurodegenerative Diseases in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 4 (26.67) | 2.80 |
| Authors | Studies |
|---|---|
| Akopyan, AA; Klyushnik, TP; Pupyshev, AB; Singh, SK; Tikhonova, MA | 1 |
| Dolai, J; Ghorai, BK; Jana, D; Jana, NR; Mandal, S; Sarkar, AK | 1 |
| Gao, F; He, W; Hu, S; Lan, Y; Li, Z; Wang, G; Wang, X; Wang, Z; Xu, B; Zhang, J; Zhao, K | 1 |
| Al-Harrasi, A; Behl, T; Bhatia, S; Bungau, S; Mehta, V; Rana, T; Sehgal, A; Singh, S | 1 |
| Caraglia, M; Hosseinpour-Moghaddam, K; Sahebkar, A | 1 |
| Emanuele, E | 1 |
| Chen, CM; Chen, WL; Hsieh-Li, HM; Hsu, KC; Huang, SH; Huang, YJ; Kung, PJ; Lee, GC; Lee-Chen, GJ; Lin, CH; Lin, JY; Tao, YC; Wang, CM; Wu, YR; Yang, JM | 1 |
| Fuentes, JM; Gómez-Sánchez, R; González-Polo, RA; Pedro, JM; Pizarro-Estrella, E; Rodríguez-Arribas, M; Yakhine-Diop, SM | 1 |
| Bento, CF; Deretic, V; Rubinsztein, DC | 1 |
| Barui, AK; Hu, Y; Jin, PP; Lin, J; Patra, CR; Ruan, RQ; Shi, SS; Wei, PF; Wen, LP; Zhang, HR; Zhang, JQ; Zhang, L; Zhang, YJ; Zhou, W | 1 |
| Bajaj, L; Bondar, VV; Bremner, L; Chaudhury, A; Cooper, JD; Lotfi, P; Neilson, JR; Nelvagal, HR; Pal, R; Palmieri, M; Pautler, RG; Pereira, FA; Rodney, GG; Saleem, U; Sanagasetti, D; Sardiello, M; Seymour, ML; Stinnett, GR; Tse, DY; Wu, SM | 1 |
| Béranger, F; Crozet, C; Goldsborough, A; Lehmann, S | 1 |
| Rubinsztein, DC; Sarkar, S | 1 |
| Aguib, Y; Baier, M; Ertmer, A; Gilch, S; Heiseke, A; Riemer, C; Schätzl, HM | 1 |
| Irace, G; Sirangelo, I | 1 |
8 review(s) available for trehalose and Neurodegenerative Diseases
| Article | Year |
|---|---|
Disaccharide trehalose in experimental therapies for neurodegenerative disorders: Molecular targets and translational potential.
Topics: Animals; Autophagy; Disaccharides; Humans; Neurodegenerative Diseases; Therapies, Investigational; TOR Serine-Threonine Kinases; Trehalose | 2022 |
Exploring the Role of Autophagy Dysfunction in Neurodegenerative Disorders.
Topics: Animals; Autophagosomes; Autophagy; Cell Survival; Humans; Lysosomes; Metformin; MTOR Inhibitors; Neurodegenerative Diseases; Neurons; Trehalose | 2021 |
Autophagy induction by trehalose: Molecular mechanisms and therapeutic impacts.
Topics: Animals; Autophagy; Disaccharides; Homeostasis; Humans; Neoplasms; Neurodegenerative Diseases; Trehalose | 2018 |
Can trehalose prevent neurodegeneration? Insights from experimental studies.
Topics: Animals; Autophagy; Disease Models, Animal; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Protein Stability; Trehalose | 2014 |
Is the Modulation of Autophagy the Future in the Treatment of Neurodegenerative Diseases?
Topics: Animals; Autophagy; Disease Models, Animal; Food; Humans; Isothiocyanates; Lithium; Neurodegenerative Diseases; Resveratrol; Sirolimus; Spermidine; Stilbenes; Sulfoxides; Trehalose; Valproic Acid | 2015 |
Therapeutic targeting of autophagy in neurodegenerative and infectious diseases.
Topics: Autophagy; Communicable Diseases; Gene Expression Regulation; Humans; Models, Biological; Neurodegenerative Diseases; Oxazoles; Rilmenidine; Signal Transduction; Trehalose | 2015 |
Small molecule enhancers of autophagy for neurodegenerative diseases.
Topics: Animals; Autophagy; Inositol; Models, Biological; Neurodegenerative Diseases; Protein Folding; Protein Kinases; Proteins; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Trehalose | 2008 |
Inhibition of aggregate formation as therapeutic target in protein misfolding diseases: effect of tetracycline and trehalose.
Topics: Amyloid; Amyloidogenic Proteins; Humans; Molecular Targeted Therapy; Neurodegenerative Diseases; Protein Synthesis Inhibitors; Proteins; Proteostasis Deficiencies; Tetracycline; Trehalose | 2010 |
7 other study(ies) available for trehalose and Neurodegenerative Diseases
| Article | Year |
|---|---|
Biodegradable Poly(trehalose) Nanoparticle for Preventing Amyloid Beta Aggregation and Related Neurotoxicity.
Topics: Amyloid beta-Peptides; Humans; Nanoparticles; Neurodegenerative Diseases; Polymers; Trehalose | 2023 |
An Experimental Model of Neurodegenerative Disease Based on Porcine Hemagglutinating Encephalomyelitis Virus-Related Lysosomal Abnormalities.
Topics: Animals; Betacoronavirus 1; Cell Line, Tumor; Coronavirus Infections; Disease Models, Animal; DNA-Binding Proteins; Lysosomes; Male; Mice, Inbred BALB C; Neurodegenerative Diseases; Progranulins; Swine; Trehalose | 2020 |
The potential of lactulose and melibiose, two novel trehalase-indigestible and autophagy-inducing disaccharides, for polyQ-mediated neurodegenerative disease treatment.
Topics: Animals; Autophagy; Cell Line; Computer-Aided Design; Digestion; Disease Models, Animal; Drug Design; Drug Stability; Hydrogen Bonding; Hydrolysis; Lactulose; Melibiose; Mice, Transgenic; Molecular Docking Simulation; Molecular Structure; Neurodegenerative Diseases; Neuroprotective Agents; Peptides; Protein Aggregates; Purkinje Cells; Structure-Activity Relationship; TATA-Box Binding Protein; Time Factors; Transfection; Trehalase; Trehalose | 2015 |
Differential ERK activation during autophagy induced by europium hydroxide nanorods and trehalose: Maximum clearance of huntingtin aggregates through combined treatment.
Topics: Adenine; Androstadienes; Animals; Autophagy; Autophagy-Related Protein 5; Butadienes; Cell Line, Tumor; Cell Survival; Chloroquine; Europium; Extracellular Signal-Regulated MAP Kinases; Green Fluorescent Proteins; HeLa Cells; Humans; Huntingtin Protein; Hydroxides; Lysosomes; Macrolides; Mice; Microscopy, Fluorescence; Microtubule-Associated Proteins; Nanotubes; Nerve Tissue Proteins; Neurodegenerative Diseases; Nitriles; Phagosomes; Phosphorylation; RNA, Small Interfering; Signal Transduction; TOR Serine-Threonine Kinases; Trehalose; Wortmannin | 2015 |
mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases.
Topics: Animals; Astrocytes; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Brain; Cell Nucleus; Disease Models, Animal; Fibroblasts; Gene Knockdown Techniques; HeLa Cells; Heterocyclic Compounds, 3-Ring; Humans; Male; Mechanistic Target of Rapamycin Complex 1; Membrane Glycoproteins; Mice; Mice, Transgenic; Molecular Chaperones; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Phosphorylation; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Signal Transduction; Trehalose | 2017 |
Trehalose impairs aggregation of PrPSc molecules and protects prion-infected cells against oxidative damage.
Topics: Animals; Cell Line; Cytoprotection; Detergents; Endopeptidase K; Mice; Neurodegenerative Diseases; Neurons; Oxidative Stress; PrPSc Proteins; Trehalose | 2008 |
Autophagy induction by trehalose counteracts cellular prion infection.
Topics: Animals; Autophagy; Benzamides; Cell Line; Dose-Response Relationship, Drug; Humans; Imatinib Mesylate; Mice; Neurodegenerative Diseases; Neurons; Piperazines; Prion Diseases; Prions; Pyrimidines; RNA, Small Interfering; Time Factors; Trehalose | 2009 |