trehalose has been researched along with Koch's Disease in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.14) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 6 (21.43) | 29.6817 |
| 2010's | 6 (21.43) | 24.3611 |
| 2020's | 8 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Geng, P; Hong, X; Li, X; Liu, G; Ni, D | 1 |
| Banahene, N; Biegas, KJ; Gepford, DM; Hsu, YP; Lepori, I; Murphy, BA; Obregón-Henao, A; Siegrist, MS; Swanson, DH; Swarts, BM; Taylor, ZE; Van Nieuwenhze, MS | 1 |
| Kaprelyants, AS; Shleeva, MO | 1 |
| Angera, IJ; Banahene, N; Dzigba, P; Greenlee-Wacker, MC; Kavunja, HW; Rylski, AK; Swarts, BM | 1 |
| Buhl, C; Child, R; Ettenger, G; Evans, JT; Holley, D; Miller, SM; Rasheed, OK; Ryter, KT; Smith, AJ | 1 |
| Alexander, C; Christensen, D; Dichtl, S; Lang, R; Murray, PJ; Pfeffer, K; Schäfer, J; Schick, J; Schleicher, U; Sorg, U | 1 |
| Kapoor, S; Kumar, G; Narayan, R | 1 |
| Calderon, R; Holzheimer, M; Ishikawa, E; Jimenez, J; Lecca, L; Lopez, K; Minnaard, AJ; Moody, DB; Murray, MB; Reijneveld, JF; Suliman, S; Van Rhijn, I; Yamasaki, S; Young, DC | 1 |
| Bertozzi, CR; Kamariza, M; Shieh, P | 1 |
| Cho, SN; Ehrt, S; Eoh, H; Eum, SY; Lee, JJ; Lee, SK; Nathan, TO; Song, N; Swarts, BM | 1 |
| Beau, JM; Bourdreux, Y; De Libero, G; Garcia-Alles, LF; Gau, B; Gilleron, M; Lemétais, A; Lepore, M; Mori, L; Prandi, J; Puzo, G | 1 |
| Alarico, S; Empadinhas, N; Maranha, A; Mendes, V; Nobre, A | 1 |
| Al Dulayymi, JR; Baird, MS; Baols, KS; Beyaert, R; Denis, O; Huygen, K; L'Homme, L; Lang, R; Legrand, S; Lehebel, P; Mohammed, MO; Piette, J; Potemberg, G; Romano, M; Sahb, MM; Tima, HG | 1 |
| Alber, M; Bornemann, S; Deenen, R; DeJesus, MA; Ehrt, S; Hartman, T; Ioerger, TR; Jacobs, WR; Kalscheuer, R; Köhrer, K; Koliwer-Brandl, H; Korte, J; Syson, K; Trujillo, CM | 1 |
| Alcaide, J; Julián, E; Lanéelle, MA; Luquin, M; Matas, L; Pérez, A | 1 |
| Bordat, Y; Gicquel, B; Giroux, S; Jackson, M; Kolattukudy, PE; Neyrolles, O; Prevost, MC; Rousseau, C; Sirakova, TD | 1 |
| Apt, AS; Driscoll, PC; Harris, R; McAlister, MS; Mischenko, VV; Murphy, HN; Robertson, BD; Stewart, GR; Young, DB | 1 |
| Bertozzi, CR; Cox, JS; Jain, M; Kumar, P; Leary, JA; Leavell, MD; Lin, FL; Petzold, CJ; Schelle, MW | 1 |
| Barilone, N; Boudou, F; Chesne-Seck, ML; Cole, ST; Gicquel, B; Gonzalo Asensio, J; Gopaul, DN; Jackson, M; Kolattukudy, PE; Martín, C | 1 |
| Handzel, V; Laszlo, A; Vera-Cabrera, L | 1 |
| Baer, HH; Goren, MB; Handzel, V; Laszlo, A; Papa, F | 1 |
| Baer, HH; Wu, X | 1 |
| Lagrange, PH; Molimard, M; Molina, JM; Oksenhendler, E; Perronne, C; Simonney, N | 1 |
| Lanéelle, MA; Martín-Casabona, N; Tórtola, MT | 1 |
| Ausina, V; Daffé, M; Julián, E; Lanéelle, MA; Luquin, M; Muñoz, M; Torrelles, J | 1 |
| Tonge, PJ | 1 |
| Kato, M | 1 |
| Kato, A | 1 |
2 review(s) available for trehalose and Koch's Disease
| Article | Year |
|---|---|
Hypobiosis of Mycobacteria: Biochemical Aspects.
Topics: Animals; Anti-Bacterial Agents; Mice; Mycobacterium tuberculosis; Trehalose; Tuberculosis | 2023 |
The molecular biology of mycobacterial trehalose in the quest for advanced tuberculosis therapies.
Topics: Animals; Antitubercular Agents; Humans; Mycobacterium; Trehalose; Tuberculosis | 2014 |
26 other study(ies) available for trehalose and Koch's Disease
| Article | Year |
|---|---|
Optimization of nitrofuranyl calanolides for the fluorescent detection of Mycobacterium tuberculosis.
Topics: Animals; Fluorescent Dyes; Humans; Mice; Mycobacterium tuberculosis; Pyranocoumarins; Single-Cell Analysis; Sputum; Trehalose; Tuberculosis | 2022 |
A Far-Red Molecular Rotor Fluorogenic Trehalose Probe for Live Mycobacteria Detection and Drug-Susceptibility Testing.
Topics: Fluorescent Dyes; Humans; Molecular Probes; Mycobacterium tuberculosis; Trehalose; Tuberculosis | 2023 |
Immune Targeting of Mycobacteria through Cell Surface Glycan Engineering.
Topics: Cell Membrane; Humans; Mycobacterium; Mycobacterium smegmatis; Mycobacterium tuberculosis; Trehalose; Tuberculosis | 2023 |
Aryl Trehalose Derivatives as Vaccine Adjuvants for
Topics: Adjuvants, Immunologic; Animals; Binding Sites; Cattle; Cell Line; Female; Humans; Lectins, C-Type; Mice, Inbred BALB C; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Receptors, Immunologic; Structure-Activity Relationship; Trehalose; Tuberculosis; Tuberculosis Vaccines | 2020 |
Cutting Edge: TNF Is Essential for Mycobacteria-Induced MINCLE Expression, Macrophage Activation, and Th17 Adjuvanticity.
Topics: Animals; Cells, Cultured; Etanercept; Lectins, C-Type; Macrophage Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mycobacterium bovis; Receptors, Immunologic; Receptors, Tumor Necrosis Factor, Type I; Sugar Phosphates; Th17 Cells; Trehalose; Tuberculosis; Tumor Necrosis Factor-alpha | 2020 |
Chemical Tools for Illumination of Tuberculosis Biology, Virulence Mechanisms, and Diagnosis.
Topics: Alcohol Oxidoreductases; Animals; Bacterial Proteins; Cell Wall; Fluorescent Dyes; Humans; Lipids; Molecular Probes; Mycobacterium tuberculosis; Peptidoglycan; Sulfatases; Trehalose; Tuberculosis; Virulence | 2020 |
Synthetic mycobacterial diacyl trehaloses reveal differential recognition by human T cell receptors and the C-type lectin Mincle.
Topics: Antigen-Presenting Cells; Antigens, CD1; Host-Pathogen Interactions; Humans; Interferon-gamma; Lectins, C-Type; Lipids; Mycobacterium tuberculosis; Receptors, Antigen, T-Cell; T-Lymphocytes; Trehalose; Tuberculosis | 2021 |
Imaging Mycobacterial Trehalose Glycolipids.
Topics: Cell Wall; Fluorescein; Glycolipids; Humans; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Imaging; Mycobacterium tuberculosis; Naphthalimides; Sputum; Staining and Labeling; Trehalose; Tuberculosis | 2018 |
Transient drug-tolerance and permanent drug-resistance rely on the trehalose-catalytic shift in Mycobacterium tuberculosis.
Topics: Adenosine Triphosphate; Anti-Bacterial Agents; Bacterial Proteins; Catalysis; Drug Resistance, Multiple, Bacterial; Glucosyltransferases; Humans; Mycobacterium tuberculosis; Trehalose; Tuberculosis | 2019 |
Simplified deoxypropionate acyl chains for Mycobacterium tuberculosis sulfoglycolipid analogues: chain length is essential for high antigenicity.
Topics: Antigens, Bacterial; Glycolipids; Humans; Mycobacterium tuberculosis; Trehalose; Tuberculosis; Tuberculosis Vaccines | 2013 |
Inflammatory Properties and Adjuvant Potential of Synthetic Glycolipids Homologous to Mycolate Esters of the Cell Wall of Mycobacterium tuberculosis.
Topics: Adjuvants, Immunologic; Animals; Bone Marrow Cells; Cell Differentiation; Cell Wall; Cells, Cultured; Dendritic Cells; Esters; Glucose; Glycolipids; Inflammasomes; Inflammation; Interleukin-6; Lectins, C-Type; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mycobacterium tuberculosis; Mycolic Acids; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species; Trehalose; Tuberculosis; Tumor Necrosis Factor-alpha | 2017 |
Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice.
Topics: Animals; Bacterial Proteins; Chromatography, Thin Layer; Disease Models, Animal; Female; Gene Expression Profiling; Gene Knockdown Techniques; Glucosyltransferases; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Phosphoric Monoester Hydrolases; Real-Time Polymerase Chain Reaction; Sugar Phosphates; Trehalose; Tuberculosis | 2016 |
Serodiagnosis of tuberculosis: comparison of immunoglobulin A (IgA) response to sulfolipid I with IgG and IgM responses to 2,3-diacyltrehalose, 2,3,6-triacyltrehalose, and cord factor antigens.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Bacterial; Antigens, Bacterial; Child; Child, Preschool; Cord Factors; Female; Glycolipids; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Infant; Male; Middle Aged; Mycobacterium tuberculosis; Sensitivity and Specificity; Serologic Tests; Trehalose; Tuberculosis; Virulence Factors | 2002 |
Deficiency in mycolipenate- and mycosanoate-derived acyltrehaloses enhances early interactions of Mycobacterium tuberculosis with host cells.
Topics: Animals; Fatty Acids; Female; Glycolipids; HeLa Cells; Humans; Liver; Lung; Macrophages; Mice; Mice, Inbred BALB C; Models, Biological; Mutation; Mycobacterium tuberculosis; Mycolic Acids; Phagocytosis; Polysaccharides, Bacterial; Spleen; Trehalose; Tuberculosis | 2003 |
The OtsAB pathway is essential for trehalose biosynthesis in Mycobacterium tuberculosis.
Topics: alpha-Amylases; Animals; Archaeal Proteins; Catalysis; Cell Proliferation; Cell Wall; Disaccharides; Disease Models, Animal; DNA Primers; Glucose; Glucose-6-Phosphate; Glucosyltransferases; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Mice, Knockout; Mycobacterium tuberculosis; Phosphoric Monoester Hydrolases; Recombinant Proteins; Time Factors; Trehalose; Tuberculosis | 2005 |
PapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1.
Topics: Acyltransferases; Animals; Bacterial Proteins; Glycolipids; Mice; Multigene Family; Mycobacterium tuberculosis; Trehalose; Tuberculosis; Virulence Factors | 2007 |
A point mutation in the two-component regulator PhoP-PhoR accounts for the absence of polyketide-derived acyltrehaloses but not that of phthiocerol dimycocerosates in Mycobacterium tuberculosis H37Ra.
Topics: Animals; Bacterial Proteins; Circular Dichroism; Electrophoretic Mobility Shift Assay; Gene Deletion; Genetic Complementation Test; Glycolipids; Lipids; Macrolides; Mice; Mycobacterium tuberculosis; Point Mutation; Promoter Regions, Genetic; Protein Binding; Recombinant Proteins; Trehalose; Tuberculosis; Virulence | 2008 |
Development of an enzyme-linked immunosorbent assay (ELISA) combined with a streptavidin-biotin and enzyme amplification method to detect anti-2,3-di-o-acyltrehalose (DAT) antibodies in patients with tuberculosis.
Topics: Antibodies, Bacterial; Antigens, Bacterial; Bacterial Proteins; Biotin; Dose-Response Relationship, Immunologic; Enzyme-Linked Immunosorbent Assay; Glycolipids; Humans; Mycobacterium tuberculosis; Polysaccharides, Bacterial; Streptavidin; Trehalose; Tuberculosis | 1994 |
Screening of synthetic trehalose 6,6'-diesters and trehalose 6-monoesters as potential immunoreactants for the serodiagnosis of tuberculosis.
Topics: Animals; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin G; Mycobacterium tuberculosis; Rabbits; Reference Values; Serologic Tests; Trehalose; Tuberculosis | 1994 |
Synthesis of alpha,alpha-trehalose 2,3- and 2,3'-diesters with palmitic and stearic acid: potential immunoreactants for the serodiagnosis of tuberculosis.
Topics: Antigen-Antibody Reactions; Carbohydrate Sequence; Esters; Glycolipids; Indicators and Reagents; Molecular Sequence Data; Palmitic Acid; Palmitic Acids; Serologic Tests; Stearic Acids; Trehalose; Tuberculosis | 1993 |
Analysis of the immunological humoral response to Mycobacterium tuberculosis glycolipid antigens (DAT, PGLTb1) for diagnosis of tuberculosis in HIV-seropositive and -seronegative patients.
Topics: Adult; Aged; Antibodies, Bacterial; Antigens, Bacterial; Glycolipids; HIV Seronegativity; HIV Seropositivity; Humans; Immunoenzyme Techniques; Immunoglobulin G; Middle Aged; Mycobacterium tuberculosis; Trehalose; Tuberculosis | 1995 |
Comparison of two 2,3-diacyl trehalose antigens from Mycobacterium tuberculosis and Mycobacterium fortuitum for serology in tuberculosis patients.
Topics: Antibodies, Bacterial; Antigens, Bacterial; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin G; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Serotyping; Trehalose; Tuberculosis | 1996 |
Occurrence of an antigenic triacyl trehalose in clinical isolates and reference strains of Mycobacterium tuberculosis.
Topics: Antibodies, Bacterial; Antibody Specificity; Antigens, Bacterial; Enzyme-Linked Immunosorbent Assay; Glycolipids; Humans; Magnetic Resonance Spectroscopy; Mycobacterium tuberculosis; Serologic Tests; Trehalose; Tuberculosis | 1997 |
Another brick in the wall.
Topics: Acyltransferases; Antibodies, Bacterial; Antigens, Bacterial; Azides; Binding Sites; Catalytic Domain; Cell Wall; Cord Factors; Fibronectins; Humans; Mycobacterium tuberculosis; Protein Conformation; Trehalose; Tuberculosis | 2000 |
[Significance of cord factor in tuberculosis].
Topics: Antibodies, Bacterial; Disaccharides; Glycolipids; Humans; Mycobacterium tuberculosis; Trehalose; Tuberculosis | 1974 |
[Symposium II: The role of cord factor in tuberculosis].
Topics: Animals; Antibodies; Disaccharides; Glycolipids; Mice; Mycobacterium tuberculosis; Rabbits; Trehalose; Tuberculosis | 1974 |