Page last updated: 2024-08-18

trehalose and Innate Inflammatory Response

trehalose has been researched along with Innate Inflammatory Response in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (43.48)24.3611
2020's13 (56.52)2.80

Authors

AuthorsStudies
Bahri, F; Khaksari, M; Movahedinia, S; Nazari-Robati, M; Rajizadeh, MA; Shafiei, B1
Cagini, C; Di Lascio, G; Lupidi, M; Mariniello, M; Meschini, G; Messina, M; Torroni, G1
Alimi, H; Aminzadeh, B; Ansari, MA; Bagheri, RK; Banach, M; Bioletto, F; Bo, S; Ehsani, F; Emami, F; Ganjali, S; Jamialahmadi, T; Rajabi, O; Sahebkar, A1
Huang, Q; Huang, W; Li, E; Wang, L; Xiang, Z; Zhou, J1
Choi, GE; Choi, WS; Jang, YJ; Kim, HS; Kim, SJ; Lee, J; Park, HJ; Yi, E1
Cuzzocrea, S; Esposito, E; Filippone, A; Greco, V; Naletova, I; Paterniti, I; Rizzarelli, E; Sciuto, S1
Adams, JA; Ballentine, S; Chiquetto Paracatu, L; DeBosch, BJ; Dong, Q; Greenberg, ZJ; Higgins, CB; Li, W; Milewska, M; Schuettpelz, LG; Sun, J; Wandzik, I; Ward, MH; Zhang, Y1
D'souza, S; Ghosh, A; Jeyabalan, N; Nelson, EJR; Panigrahi, T; Sethu, S; Shetty, R; Shivakumar, S1
Ban, J; Chen, J; Chen, S; Chen, Y; He, X; He, Y; Li, C; Liu, F; Wei, Y1
Chen, L; Fu, Y; Lu, Y; Shao, C; Sun, H; Wu, N; Yan, D; Yao, Q; Zhou, M1
Bian, F; Chen, D; Chen, X; Gao, N; Li, DQ; Li, J; Liu, Z; Pflugfelder, SC; Qin, W; Xiao, Y1
Ganesh, S; Sinha, P; Verma, B1
Bastin, AR; Doustimotlagh, AH; Nazari-Robati, M; Sadeghi, A; Sadeghi, H1
Abd-Elsalam, WH; Abouelatta, SM; Saber, MM1
Estrada, AL; Hudson, WM; LaRocca, TJ; Pagliassotti, MJ; Seals, DR; Wang, D; Wei, Y; Zigler, ML1
Barrachina, MD; Calatayud, S; Cosín-Roger, J; Esplugues, JV; Hernández, C; Macias-Ceja, DC; Ortiz-Masiá, D; Salvador, P1
Cooper, JD; Di Ronza, A; Lotfi, P; Martano, G; Passafaro, M; Pereira, FA; Sardiello, M; Seymour, ML; Tse, DY; Wu, SM1
Akbari, M; Khaksari, M; Mirzaee, M; Nazari-Robati, M1
Agrawal, A; Chakraborty, K; Chakraborty, S; Ghosh, B; Krishnan, V; Mabalirajan, U; Maity, S; Makhija, L; Rehman, R1
Shen, G; Zhang, X; Zhang, Z; Zhao, J1
Al Dulayymi, JR; Baird, MS; Baols, KS; Beyaert, R; Denis, O; Huygen, K; L'Homme, L; Lang, R; Legrand, S; Lehebel, P; Mohammed, MO; Piette, J; Potemberg, G; Romano, M; Sahb, MM; Tima, HG1
Chung, UI; Echigo, R; Fujisawa, A; Karatsu, K; Kayasuga-Kariya, Y; Kita, Y; Mochizuki, M; Nakamura, M; Ohto, T; Sasaki, N; Shimizu, T; Shimohata, N; Suzuki, S; Yano, F1
Henson, GD; LaRocca, TJ; Pierce, GL; Seals, DR; Sindler, AL; Thorburn, A1

Trials

3 trial(s) available for trehalose and Innate Inflammatory Response

ArticleYear
Dry eye and inflammation of the ocular surface after cataract surgery: effectiveness of a tear film substitute based on trehalose/hyaluronic acid vs hyaluronic acid to resolve signs and symptoms.
    Journal of cataract and refractive surgery, 2021, 11-01, Volume: 47, Issue:11

    Topics: Cataract; Dry Eye Syndromes; Humans; Hyaluronic Acid; Inflammation; Prospective Studies; Tears; Trehalose

2021
The effect of trehalose administration on vascular inflammation in patients with coronary artery disease.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 147

    Topics: Anti-Inflammatory Agents; Aorta; Carotid Arteries; Coronary Artery Disease; Double-Blind Method; Humans; Inflammation; Myocardial Infarction; Trehalose; Vascular Diseases

2022
Trehalose augments autophagy to mitigate stress induced inflammation in human corneal cells.
    The ocular surface, 2019, Volume: 17, Issue:4

    Topics: Autophagy; Biomarkers; Blotting, Western; Cells, Cultured; Cornea; Cytokines; Dry Eye Syndromes; Enzyme-Linked Immunosorbent Assay; Female; Humans; Inflammation; Male; Prospective Studies; Single-Blind Method; Tears; Trehalose

2019

Other Studies

20 other study(ies) available for trehalose and Innate Inflammatory Response

ArticleYear
Improving SIRT1 by trehalose supplementation reduces oxidative stress, inflammation, and histopathological scores in the kidney of aged rats.
    Journal of food biochemistry, 2021, Volume: 45, Issue:10

    Topics: Animals; Dietary Supplements; Health Promotion; Inflammation; Kidney; Male; Oxidative Stress; Rats; Sirtuin 1; Trehalose

2021
Autophagy Protects Ocular Surface Against Overactivated Inflammation by Degrading Retinoic Acid-Induced Gene-I in Human Conjunctival Epithelial Cells.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2022, Volume: 38, Issue:5

    Topics: Autophagy; Dry Eye Syndromes; Epithelial Cells; Humans; Inflammation; RNA; Trehalose; Tretinoin

2022
Sweet taste receptor agonists attenuate macrophage IL-1β expression and eosinophilic inflammation linked to autophagy deficiency in myeloid cells.
    Clinical and translational medicine, 2022, Volume: 12, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Autophagy; Eosinophilia; Inflammation; Macrophages; Mice; Saccharin; Sinusitis; Taste; Trehalose

2022
Trehalose-Carnosine Prevents the Effects of Spinal Cord Injury Through Regulating Acute Inflammation and Zinc(II) Ion Homeostasis.
    Cellular and molecular neurobiology, 2023, Volume: 43, Issue:4

    Topics: Animals; Apoptosis; Carnosine; Homeostasis; Inflammation; Nerve Growth Factors; Rats; Spinal Cord; Spinal Cord Injuries; Trehalose; Zinc

2023
The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytes.
    The Journal of biological chemistry, 2023, Volume: 299, Issue:2

    Topics: Animals; Diet, High-Fat; Hepatocytes; Inflammation; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Tetraspanin 25; Tetraspanins; Trehalose

2023
Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages.
    Cells, 2020, 01-04, Volume: 9, Issue:1

    Topics: Animals; Apoptosis; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Nucleus; Crystallization; Cytokines; Disease Models, Animal; Inflammation; Inflammation Mediators; Lysosomes; Macrophages, Alveolar; Male; Mice, Inbred C57BL; Protein Transport; Pulmonary Fibrosis; Silicon Dioxide; Substrate Specificity; Trehalose

2020
Trehalose attenuates TGF-β1-induced fibrosis of hSCFs by activating autophagy.
    Molecular and cellular biochemistry, 2020, Volume: 470, Issue:1-2

    Topics: Autophagy; Cells, Cultured; Collagen Type I; Conjunctiva; Disease Progression; Extracellular Matrix; Fibroblasts; Fibronectins; Fibrosis; Humans; Inflammation; Myofibroblasts; Phosphorylation; Sirolimus; Smad2 Protein; Transforming Growth Factor beta1; Trehalose

2020
Trehalose Induces Autophagy Against Inflammation by Activating TFEB Signaling Pathway in Human Corneal Epithelial Cells Exposed to Hyperosmotic Stress.
    Investigative ophthalmology & visual science, 2020, 08-03, Volume: 61, Issue:10

    Topics: Adolescent; Adult; Aged; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Interleukin-8; Middle Aged; Osmotic Pressure; Real-Time Polymerase Chain Reaction; Signal Transduction; Trehalose; Tumor Necrosis Factor-alpha; Young Adult

2020
Trehalose Ameliorates Seizure Susceptibility in Lafora Disease Mouse Models by Suppressing Neuroinflammation and Endoplasmic Reticulum Stress.
    Molecular neurobiology, 2021, Volume: 58, Issue:3

    Topics: Animals; Autophagy; Brain; Calcium-Binding Proteins; Disease Models, Animal; Disease Susceptibility; Endoplasmic Reticulum Stress; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Gliosis; Glucans; Inflammation; Lafora Disease; Membrane Proteins; Mice, Knockout; Microfilament Proteins; Nerve Tissue Proteins; Pentylenetetrazole; Protein Tyrosine Phosphatases, Non-Receptor; Seizures; Trehalose; Ubiquitin-Protein Ligases

2021
Trehalose and N-Acetyl Cysteine Alleviate Inflammatory Cytokine Production and Oxidative Stress in LPS-Stimulated Human Peripheral Blood Mononuclear Cells.
    Immunological investigations, 2022, Volume: 51, Issue:4

    Topics: Acetylcysteine; Anti-Inflammatory Agents; Antioxidants; Cytokines; Glutathione Peroxidase; Humans; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Leukocytes, Mononuclear; Lipopolysaccharides; Malondialdehyde; NF-kappa B; Oxidative Stress; Trehalose; Tumor Necrosis Factor-alpha

2022
Trehalosomes: Colon targeting trehalose-based green nanocarriers for the maintenance of remission in inflammatory bowel diseases.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2021, Volume: 166

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Colon; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Design; Inflammation; Inflammatory Bowel Diseases; Oxidative Stress; Plant Extracts; Protective Agents; Rabbits; Trehalose

2021
Trehalose supplementation reduces hepatic endoplasmic reticulum stress and inflammatory signaling in old mice.
    The Journal of nutritional biochemistry, 2017, Volume: 45

    Topics: Aging; AMP-Activated Protein Kinase Kinases; Animals; Autophagy; Biomarkers; Blood Glucose; Dietary Supplements; Endoplasmic Reticulum Stress; Inflammation; Liver; Male; Mice, Inbred C57BL; Niacinamide; Protein Kinases; Trehalose; Triglycerides; Unfolded Protein Response

2017
Stimulation of autophagy prevents intestinal mucosal inflammation and ameliorates murine colitis.
    British journal of pharmacology, 2017, Volume: 174, Issue:15

    Topics: Administration, Rectal; Animals; Autophagy; Betacyanins; Colitis; Female; Inflammation; Injections, Intraperitoneal; Intestinal Mucosa; Male; Mice; Mice, Inbred BALB C; Sirolimus; Trehalose; Trinitrobenzenesulfonic Acid

2017
Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency.
    Autophagy, 2018, Volume: 14, Issue:8

    Topics: Acetylglucosaminidase; Animals; Astrocytes; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Brain; Cell Nucleus; Disease Progression; Gene Regulatory Networks; Inflammation; Lysosomes; Mice, Inbred C57BL; Mice, Knockout; Mucopolysaccharidosis III; Retinal Bipolar Cells; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Survival Analysis; Transcriptional Activation; Trehalose; Vacuoles

2018
Trehalose attenuates spinal cord injury through the regulation of oxidative stress, inflammation and GFAP expression in rats.
    The journal of spinal cord medicine, 2019, Volume: 42, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Glial Fibrillary Acidic Protein; Inflammation; Male; Oxidative Stress; Rats; Rats, Wistar; Recovery of Function; Spinal Cord Injuries; Trehalose

2019
Chemical chaperones mitigate experimental asthma by attenuating endoplasmic reticulum stress.
    American journal of respiratory cell and molecular biology, 2014, Volume: 50, Issue:5

    Topics: Airway Remodeling; Animals; Asthma; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Glycerol; Inflammation; Lung; Male; Methylamines; Mice; Mice, Inbred BALB C; Molecular Chaperones; Phenylbutyrates; Protein Folding; Trehalose; Unfolded Protein Response

2014
Enhanced osteogenic activity and anti-inflammatory properties of Lenti-BMP-2-loaded TiO₂ nanotube layers fabricated by lyophilization following trehalose addition.
    International journal of nanomedicine, 2016, Volume: 11

    Topics: Animals; Anti-Inflammatory Agents; Bone Morphogenetic Protein 2; Cell Differentiation; Cells, Cultured; Freeze Drying; Inflammation; Lentivirus; Male; Mesenchymal Stem Cells; Nanotubes; Osseointegration; Osteogenesis; Rats; Rats, Inbred F344; Titanium; Trehalose

2016
Inflammatory Properties and Adjuvant Potential of Synthetic Glycolipids Homologous to Mycolate Esters of the Cell Wall of Mycobacterium tuberculosis.
    Journal of innate immunity, 2017, Volume: 9, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Bone Marrow Cells; Cell Differentiation; Cell Wall; Cells, Cultured; Dendritic Cells; Esters; Glucose; Glycolipids; Inflammasomes; Inflammation; Interleukin-6; Lectins, C-Type; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mycobacterium tuberculosis; Mycolic Acids; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species; Trehalose; Tuberculosis; Tumor Necrosis Factor-alpha

2017
Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage.
    Journal of translational medicine, 2012, Apr-30, Volume: 10

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Hemolysis; Humans; Inflammation; Lipid Peroxidation; Male; Mice; NF-kappa B; Oxidative Stress; Rabbits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Subarachnoid Hemorrhage; Trehalose; Vasospasm, Intracranial

2012
Translational evidence that impaired autophagy contributes to arterial ageing.
    The Journal of physiology, 2012, Jul-15, Volume: 590, Issue:14

    Topics: Adult; Aged; Aging; Animals; Arteries; Autophagy; Cytokines; Endothelium, Vascular; Female; Forearm; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Oxidative Stress; Regional Blood Flow; Superoxides; Trehalose; Vasodilation

2012