trehalose has been researched along with Idiopathic Parkinson Disease in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 6 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akopyan, AA; Dubrovina, NI; Ovsyukova, MV; Pupyshev, AB; Tenditnik, MV; Tikhonova, MA | 1 |
| Choi, HJ; Huh, YE; Kwon, Y; Moon, SH | 1 |
| Correia, MAS; Gallardo, E; Gonçalves, AM; Oliveira, AE; Oliveira, DM; Passarinha, LA; Pedro, AQ; Queiroz, JA; Romão, MJ; Santos, MFA | 1 |
| Garcia-Garcia, A; Gopar-Cuevas, Y; Loera-Arias, MJ; Montes-de-Oca-Luna, R; Rodriguez-Rocha, H; Saucedo-Cardenas, O | 1 |
| Dubey, SK; K C, S; Kakoty, V; Kesharwani, P; Taliyan, R; Yang, CH | 1 |
| Dubey, SK; K C, S; Kakoty, V; Taliyan, R; Yang, CH | 1 |
| Cho, ED; Jung Ahn, W; Lee, HJ; Lee, SJ; Won Lee, K; Yoon, YS | 1 |
| Agarwal, M; Deep, S; Katyal, N; Kumar, V; Sen, R | 1 |
| Akopyan, AA; Dubrovina, NI; Korolenko, TA; Pupyshev, AB; Tenditnik, MV; Tikhonova, MA | 1 |
| Hoffmann, AC; Kazman, A; Klucken, J; Menges, S; Mielenz, D; Minakaki, G; Salvi, R; Savitskiy, S; Vicente Miranda, H; Winkler, J; Xiang, W | 1 |
| Barreto, GE; Khalifeh, M; Sahebkar, A | 1 |
| Bellomo, G; Parnetti, L | 1 |
| Brotchie, JM; He, Q; Koprich, JB; Wang, J; Wang, Y; Xiao, BG; Yu, WB | 1 |
| Darley-Usmar, V; Redmann, M; Volpicelli-Daley, L; Wani, WY; Zhang, J | 1 |
| Davies, JE; Huang, Z; Rubinsztein, DC; Sarkar, S; Tunnacliffe, A | 1 |
2 review(s) available for trehalose and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
The gut-brain connection in the pathogenicity of Parkinson disease: Putative role of autophagy.
Topics: alpha-Synuclein; Animals; Autophagy; Brain; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Parkinson Disease; Protein Aggregates; Trehalose | 2021 |
Trehalose as a promising therapeutic candidate for the treatment of Parkinson's disease.
Topics: Animals; Humans; Neuroprotective Agents; Parkinson Disease; Trehalose | 2019 |
13 other study(ies) available for trehalose and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Restoration of Parkinson's Disease-Like Deficits by Activating Autophagy through mTOR-Dependent and mTOR-Independent Mechanisms in Pharmacological and Transgenic Models of Parkinson's Disease in Mice.
Topics: Adenine; Animals; Autophagy; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Transgenic; MTOR Inhibitors; Neuroinflammatory Diseases; Neuroprotective Agents; Parkinson Disease; Parkinson Disease, Secondary; Signal Transduction; Sirolimus; Substantia Nigra; TOR Serine-Threonine Kinases; Trehalose | 2021 |
Trehalose ameliorates prodromal non-motor deficits and aberrant protein accumulation in a rotenone-induced mouse model of Parkinson's disease.
Topics: Animals; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Olfaction Disorders; Parkinson Disease; Prodromal Symptoms; Rotenone; Trehalose; Tyrosine 3-Monooxygenase | 2022 |
Thermofluor-Based Optimization Strategy for the Stabilization of Recombinant Human Soluble Catechol-
Topics: Carboxy-Lyases; Catechol O-Methyltransferase; Catechols; Cysteine; Dopamine; Estrogens; Glycerol; Humans; Ionic Liquids; Levodopa; Metanephrine; Parkinson Disease; Trehalose | 2022 |
Metformin and Trehalose-Modulated Autophagy Exerts a Neurotherapeutic Effect on Parkinson's Disease.
Topics: Aged; Animals; Autophagy; Dopamine; Humans; Metformin; Mice; Mice, Inbred C57BL; Neuroblastoma; Parkinson Disease; Trehalose | 2023 |
Neuroprotective Effects of Trehalose and Sodium Butyrate on Preformed Fibrillar Form of α-Synuclein-Induced Rat Model of Parkinson's Disease.
Topics: alpha-Synuclein; Animals; Butyric Acid; Disease Models, Animal; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Wistar; Trehalose | 2021 |
Is trehalose an autophagic inducer? Unraveling the roles of non-reducing disaccharides on autophagic flux and alpha-synuclein aggregation.
Topics: alpha-Synuclein; Animals; Autophagosomes; Autophagy; Cell Survival; Disaccharides; Humans; Lysosomes; Microtubule-Associated Proteins; Neurons; Parkinson Disease; Primary Cell Culture; Protein Aggregation, Pathological; Rats; RNA-Binding Proteins; Trehalose | 2017 |
Paradoxical Effect of Trehalose on the Aggregation of α-Synuclein: Expedites Onset of Aggregation yet Reduces Fibril Load.
Topics: alpha-Synuclein; Amyloid; Humans; Molecular Dynamics Simulation; Parkinson Disease; Protein Aggregation, Pathological; Protein Conformation; Trehalose | 2018 |
Therapeutic activation of autophagy by combined treatment with rapamycin and trehalose in a mouse MPTP-induced model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autophagy; Behavior, Animal; Cognition; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Drug Therapy, Combination; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; MPTP Poisoning; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Sirolimus; Substantia Nigra; Trehalose; Tyrosine 3-Monooxygenase | 2019 |
Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose.
Topics: alpha-Synuclein; Animals; Autophagy; Cell Line, Tumor; Escherichia coli; Glioma; Humans; Lysosomes; Neurons; Parkinson Disease; Protein Aggregation, Pathological; Rats; Rats, Wistar; Recombinant Proteins; Sirolimus; Trehalose | 2019 |
The issue of waste disposal in Parkinson's disease pathogenesis.
Topics: alpha-Synuclein; Humans; Lysosomes; Neurons; Parkinson Disease; Trehalose | 2019 |
Treatment with Trehalose Prevents Behavioral and Neurochemical Deficits Produced in an AAV α-Synuclein Rat Model of Parkinson's Disease.
Topics: alpha-Synuclein; Animals; Autophagy; Behavior, Animal; Blood Glucose; Cattle; Cell Survival; Dependovirus; Disease Models, Animal; Dopaminergic Neurons; Extremities; Female; Humans; Microtubule-Associated Proteins; Parkinson Disease; Rats, Sprague-Dawley; Solubility; Substantia Nigra; Trehalose; Tyrosine 3-Monooxygenase | 2016 |
Trehalose does not improve neuronal survival on exposure to alpha-synuclein pre-formed fibrils.
Topics: alpha-Synuclein; Animals; Apoptosis; Autophagy; Cell Survival; Humans; Mice; Neurons; Parkinson Disease; Protein Aggregation, Pathological; TOR Serine-Threonine Kinases; Trehalose | 2017 |
Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.
Topics: alpha-Synuclein; Animals; Antibiotics, Antineoplastic; Autophagy; Chlorocebus aethiops; COS Cells; HeLa Cells; Humans; Huntingtin Protein; Huntington Disease; Mice; Molecular Chaperones; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Parkinson Disease; Protein Kinases; Sirolimus; TOR Serine-Threonine Kinases; Trehalose | 2007 |