trehalose has been researched along with Dry Eye in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (13.04) | 29.6817 |
| 2010's | 9 (39.13) | 24.3611 |
| 2020's | 11 (47.83) | 2.80 |
| Authors | Studies |
|---|---|
| Cagini, C; Di Lascio, G; Lupidi, M; Mariniello, M; Meschini, G; Messina, M; Torroni, G | 1 |
| Diz-Arias, E; Fernández-Jimenez, E; Peral, A | 1 |
| Huang, Q; Huang, W; Li, E; Wang, L; Xiang, Z; Zhou, J | 1 |
| Blasco-Martínez, A; Chiambaretta, F; Del Prado Sanz, E; Farrant, S; Mateo-Orobia, AJ; Pablo-Júlvez, LE | 1 |
| D'souza, S; Ghosh, A; Jeyabalan, N; Nelson, EJR; Panigrahi, T; Sethu, S; Shetty, R; Shivakumar, S | 1 |
| Kaarniranta, K; Laihia, J | 1 |
| Mirsaitova, DR; Panova, IE; Titov, AV | 1 |
| Kucuk, B; Ozsaygili, C; Yildirim, Y | 1 |
| Anfuso, CD; Corsaro, R; Cristaldi, M; Lupo, G; Olivieri, M; Pezzino, S; Rusciano, D; Spampinato, G | 1 |
| Balestrazzi, A; Cagini, C; Di Lascio, G; Mariniello, M; Martone, G; Torroni, G | 1 |
| Brar, S; Ganesh, S; Vanga, HR | 1 |
| Esclatine, A; Hernandez, E; Labetoulle, M; Lussignol, M; Taisne, C | 1 |
| Bremond-Gignac, D; Chiambaretta, F; Doan, S | 1 |
| Cejka, C; Cejkova, J; Kubinova, S | 1 |
| Guthoff, RF; Hovakimyan, M; Ramoth, T; Stachs, O | 1 |
| Grzesiak, J; Hill-Bator, A; Marycz, K; Misiuk-Hojło, M | 1 |
| Baar, C; dos Santos, VA; Garhofer, G; Kaya, S; Nepp, J; Rosner, P; Schmetterer, L; Schmidl, D; Unterhuber, A; Werkmeister, RM; Witkowska, KJ | 1 |
| Baudouin, C; Chiambaretta, F; Doan, S; Fekih, LE; Khairallah, M; Labetoulle, M; Messaoud, R; Rocher, N | 1 |
| Chen, W; Lin, Y; Liu, M; Luyckx, J; Qu, J; Ye, Y; Zhang, J; Zhang, X | 1 |
| Baudouin, C; Chen, W; Li, J; Liu, G; Roubeix, C; Shi, S; Wang, Y | 1 |
| Guthoff, R; Hovakimyan, M; Löbler, M; Ramoth, T; Schmitz, KP; Stachs, O; Witt, M | 1 |
| Matsuo, T; Morimoto, N; Tsuchida, Y | 1 |
| Matsuo, T | 1 |
2 review(s) available for trehalose and Dry Eye
| Article | Year |
|---|---|
Trehalose for Ocular Surface Health.
Topics: Animals; Antioxidants; Clinical Trials as Topic; Cornea; Corneal Diseases; Dry Eye Syndromes; Humans; Trehalose | 2020 |
Trehalose in ophthalmology.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Clinical Trials as Topic; Cornea; Disease Models, Animal; Dry Eye Syndromes; Humans; Ophthalmology; Oxidative Stress; Rabbits; Trehalose; Ultraviolet Rays; Wound Healing | 2019 |
10 trial(s) available for trehalose and Dry Eye
| Article | Year |
|---|---|
Dry eye and inflammation of the ocular surface after cataract surgery: effectiveness of a tear film substitute based on trehalose/hyaluronic acid vs hyaluronic acid to resolve signs and symptoms.
Topics: Cataract; Dry Eye Syndromes; Humans; Hyaluronic Acid; Inflammation; Prospective Studies; Tears; Trehalose | 2021 |
Trehalose augments autophagy to mitigate stress induced inflammation in human corneal cells.
Topics: Autophagy; Biomarkers; Blotting, Western; Cells, Cultured; Cornea; Cytokines; Dry Eye Syndromes; Enzyme-Linked Immunosorbent Assay; Female; Humans; Inflammation; Male; Prospective Studies; Single-Blind Method; Tears; Trehalose | 2019 |
The short term effect of trehalose and different doses of sodium hyaluronate on anterior corneal aberrations in dry eye patients.
Topics: Aberrometry; Adult; Aged; Cornea; Dry Eye Syndromes; Female; Humans; Hyaluronic Acid; Lubricant Eye Drops; Male; Middle Aged; Prospective Studies; Treatment Outcome; Trehalose; Young Adult | 2021 |
Trehalose/sodium hyaluronate eye drops in post-cataract ocular surface disorders.
Topics: Cataract; Dry Eye Syndromes; Female; Humans; Hyaluronic Acid; Male; Ophthalmic Solutions; Prospective Studies; Tears; Trehalose | 2021 |
Comparison of efficacy of trehalose-based eye drops versus topical 0.1% Hyaluronic Acid for management of clinically significant dry eye using non-invasive investigational modalities.
Topics: Adult; Dry Eye Syndromes; Humans; Hyaluronic Acid; Middle Aged; Ophthalmic Solutions; Prospective Studies; Tears; Trehalose | 2021 |
Comparison of the effect of a hyaluronate-trehalose solution to hyaluronate alone on Ocular Surface Disease Index in patients with moderate to severe dry eye disease.
Topics: Adult; Dry Eye Syndromes; Female; Humans; Hyaluronic Acid; Male; Middle Aged; Ophthalmic Solutions; Single-Blind Method; Trehalose | 2018 |
[Characterisation of tear film dynamics after application of trehalose for treatment of dry eye].
Topics: Adult; Diagnostic Techniques, Ophthalmological; Dry Eye Syndromes; Female; Humans; Male; Middle Aged; Ophthalmic Solutions; Reproducibility of Results; Sensitivity and Specificity; Surface Tension; Tears; Treatment Outcome; Trehalose; Viscosity; Young Adult | 2013 |
Tear film thickness after treatment with artificial tears in patients with moderate dry eye disease.
Topics: Administration, Topical; Adult; Double-Blind Method; Drug Combinations; Dry Eye Syndromes; Female; Fourier Analysis; Humans; Hyaluronic Acid; Lubricant Eye Drops; Male; Middle Aged; Surveys and Questionnaires; Tears; Tomography, Optical Coherence; Trehalose; Viscosupplements | 2015 |
A randomized, controlled study of the efficacy and safety of a new eyedrop formulation for moderate to severe dry eye syndrome.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug Combinations; Dry Eye Syndromes; Female; France; Humans; Hyaluronic Acid; Male; Middle Aged; Ophthalmic Solutions; Patient Satisfaction; Surveys and Questionnaires; Treatment Outcome; Trehalose; Young Adult | 2017 |
Trehalose eye drops in the treatment of dry eye syndrome.
Topics: Adult; Aged; Double-Blind Method; Dry Eye Syndromes; Female; Fluorescein; Humans; Male; Middle Aged; Ophthalmic Solutions; Rose Bengal; Safety; Treatment Outcome; Trehalose | 2002 |
11 other study(ies) available for trehalose and Dry Eye
| Article | Year |
|---|---|
Improving ocular surface comfort in contact lens wearers.
Topics: Contact Lenses, Hydrophilic; Dry Eye Syndromes; Fluorescein; Humans; Lubricant Eye Drops; Prospective Studies; Tears; Trehalose | 2022 |
Autophagy Protects Ocular Surface Against Overactivated Inflammation by Degrading Retinoic Acid-Induced Gene-I in Human Conjunctival Epithelial Cells.
Topics: Autophagy; Dry Eye Syndromes; Epithelial Cells; Humans; Inflammation; RNA; Trehalose; Tretinoin | 2022 |
Efficacy of artificial tears containing trehalose and hyaluronic acid for dry eye disease in women aged 42-54 versus ≥ 55 years.
Topics: Dry Eye Syndromes; Female; Humans; Hyaluronic Acid; Hyperemia; Lubricant Eye Drops; Male; Tears; Trehalose | 2023 |
[The effects of a trehalose-based drug used after laser keratorefractive surgeries].
Topics: Dry Eye Syndromes; Humans; Keratomileusis, Laser In Situ; Myopia; Tears; Trehalose | 2020 |
Poly 2-methacryloyloxyethyl Phosphorylcholine Protects Corneal Cells and Contact Lenses from Desiccation Damage.
Topics: Animals; Cells, Cultured; Contact Lenses, Hydrophilic; Desiccation; Dry Eye Syndromes; Epithelium, Corneal; Humans; Hyaluronic Acid; Hypromellose Derivatives; Phosphorylcholine; Polymethacrylic Acids; Prosthesis Failure; Sodium Dodecyl Sulfate; Swine; Trehalose | 2021 |
Commercially Available Eye Drops Containing Trehalose Protect Against Dry Conditions via Autophagy Induction.
Topics: Autophagy; Dry Eye Syndromes; HeLa Cells; Humans; Lubricant Eye Drops; Trehalose; Tumor Cells, Cultured | 2021 |
Trehalose-based eye drops preserve viability and functionality of cultured human corneal epithelial cells during desiccation.
Topics: Cell Line; Cell Survival; Cells, Cultured; Desiccation; Dry Eye Syndromes; Epithelium, Corneal; Humans; Ophthalmic Solutions; Trehalose | 2014 |
Trehalose protects against ocular surface disorders in experimental murine dry eye through suppression of apoptosis.
Topics: Animals; Apoptosis; Conjunctiva; Disease Models, Animal; Drug Evaluation, Preclinical; Dry Eye Syndromes; Epithelium, Corneal; Female; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Ophthalmic Solutions; Tears; Trehalose | 2009 |
Therapeutic efficacy of trehalose eye drops for treatment of murine dry eye induced by an intelligently controlled environmental system.
Topics: Animals; Base Sequence; Cornea; Cornified Envelope Proline-Rich Proteins; Cytokines; Disease Models, Animal; DNA Primers; Dry Eye Syndromes; Female; Gene Expression Profiling; HSP70 Heat-Shock Proteins; Immunohistochemistry; Matrix Metalloproteinase 9; Membrane Proteins; Mice; Mice, Inbred C57BL; Occludin; Ophthalmic Solutions; Protein Precursors; RNA, Messenger; Trehalose | 2012 |
Evaluation of protective effects of trehalose on desiccation of epithelial cells in three dimensional reconstructed human corneal epithelium.
Topics: Cell Count; Cell Survival; Desiccation; Dry Eye Syndromes; Epithelium, Corneal; Humans; Imaging, Three-Dimensional; Microscopy, Confocal; Ophthalmic Solutions; Tight Junctions; Tissue Culture Techniques; Tomography, Optical Coherence; Trehalose | 2012 |
Trehalose protects corneal epithelial cells from death by drying.
Topics: Cell Survival; Cells, Cultured; Desiccation; Dose-Response Relationship, Drug; Dry Eye Syndromes; Epithelium, Corneal; Fluorescent Dyes; Humans; Maltose; Ophthalmic Solutions; Statistics, Nonparametric; Trehalose | 2001 |