trehalose has been researched along with Amyotrophic Lateral Sclerosis in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bernuzzi, S; Bordoni, M; Carelli, S; Cereda, C; Cristofani, R; Diamanti, L; Fantini, V; Gagliardi, S; Garofalo, M; Leone, R; Pansarasa, O; Poletti, A; Scarian, E | 1 |
| Massenzio, F; Mengoni, I; Miti, A; Monti, B; Peña-Altamira, E; Petralla, S; Piffaretti, D; Polazzi, E; Virgili, M; Zuccheri, G | 1 |
| Cicardi, ME; Cortese, K; Crippa, V; Cristofani, R; Ferrari, V; Galbiati, M; Garrè, M; Meroni, M; Messi, E; Morelli, E; Piccolella, M; Poletti, A; Rusmini, P; Tedesco, B; Vaccari, T; Vezzoli, G | 1 |
| Castillo, K; Court, FA; Hetz, C; Matus, S; Mercado, G; Nassif, M; Rojas, F; Valenzuela, V; van Zundert, B | 1 |
| Chen, S; Jia, L; Le, W; Shen, Y; Song, L; Tang, Y; Zhang, X | 1 |
| Duan, W; Guo, Y; Han, H; Hong, K; Li, C; Li, Y; Wang, J; Wang, X; Yu, X | 1 |
6 other study(ies) available for trehalose and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Lysosomes Dysfunction Causes Mitophagy Impairment in PBMCs of Sporadic ALS Patients.
Topics: Amyotrophic Lateral Sclerosis; Animals; Humans; Leukocytes, Mononuclear; Lysosomes; Mitophagy; TOR Serine-Threonine Kinases; Trehalose | 2022 |
Microglial overexpression of fALS-linked mutant SOD1 induces SOD1 processing impairment, activation and neurotoxicity and is counteracted by the autophagy inducer trehalose.
Topics: Amyotrophic Lateral Sclerosis; Animals; Autophagy; Cells, Cultured; Disease Models, Animal; Microglia; Neuroprotective Agents; Point Mutation; Rats; Rats, Wistar; Superoxide Dismutase-1; Trehalose; Up-Regulation | 2018 |
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Topics: Amyotrophic Lateral Sclerosis; Animals; Autophagosomes; Autophagy; Autophagy-Related Proteins; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Bulbo-Spinal Atrophy, X-Linked; Calcineurin; Calcium; Cell Differentiation; Cell Nucleus; Down-Regulation; Humans; Induced Pluripotent Stem Cells; Lysosomes; Membrane Proteins; Mice; Microtubule-Associated Proteins; Motor Neurons; Neuroprotection; RNA, Small Interfering; Sequestosome-1 Protein; Signal Transduction; Trehalose; Tripeptidyl-Peptidase 1; Unfolded Protein Response | 2019 |
Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons.
Topics: Amyotrophic Lateral Sclerosis; Animals; Autophagy; Cell Survival; Cytoprotection; Disease Progression; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Longevity; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Neurons; Mutation; Neuroglia; Protein Structure, Quaternary; Rats; Rats, Sprague-Dawley; Spinal Cord; Superoxide Dismutase; Transcription, Genetic; Trehalose | 2013 |
MTOR-independent, autophagic enhancer trehalose prolongs motor neuron survival and ameliorates the autophagic flux defect in a mouse model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Autophagy; Cell Survival; Disease Models, Animal; Male; Mice; Mice, Transgenic; Motor Neurons; Spinal Cord; Superoxide Dismutase; TOR Serine-Threonine Kinases; Trehalose | 2014 |
Trehalose decreases mutant SOD1 expression and alleviates motor deficiency in early but not end-stage amyotrophic lateral sclerosis in a SOD1-G93A mouse model.
Topics: Age Factors; Amyotrophic Lateral Sclerosis; Animals; Autophagy; Body Weight; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Neurons; Movement Disorders; Neurologic Examination; Statistics, Nonparametric; Superoxide Dismutase; Survival Analysis; Trehalose | 2015 |