Page last updated: 2024-08-18

trehalose and Alzheimer Disease

trehalose has been researched along with Alzheimer Disease in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's9 (64.29)24.3611
2020's4 (28.57)2.80

Authors

AuthorsStudies
Honisch, C; Hussain, R; Ruzza, P; Siligardi, G; Torni, F1
Akopyan, AA; Amstislavskaya, TG; Bashirzade, AA; Belichenko, VM; Dubrovina, NI; Fedoseeva, LA; Korolenko, TA; Ovsyukova, MV; Pupyshev, AB; Tenditnik, MV; Tikhonova, MA1
Hsiung, GR; Liu, Y; Song, W; Wang, J1
Barreto, GE; Khalifeh, M; Read, MI; Sahebkar, A1
Adlard, PA; Finkelstein, DI; Hare, DJ; Perronnes, K; Portbury, AJ; Portbury, SD; Sgambelloni, C1
Du, J; Liang, Y; Sun, B; Wang, Z; Xu, F1
Brizzee, C; Johnson, GV; Lei, Z1
Cho, WJ; Huh, JS; Ko, PW; Lau, HC; Lee, HW; Lee, IK; Lim, JO1
Karaca, I; Tamboli, IY; Tien, NT; Walter, J1
Aigaki, T; Kobayashi, T; Matsuo, T; Tsuda, M1
Abbott, NL; de Pablo, JJ; Izmitli, A; McGovern, MP; Reddy, AS; Schebor, C1
Krüger, U; Kumar, S; Mandelkow, EM; Wang, Y1
Casarejos, MJ; de Yébenes, JG; Gomez, A; Mena, MA; Perucho, J; Solano, RM1
Barkhordarian, H; Emadi, S; Liu, R; Park, CB; Sierks, MR1

Other Studies

14 other study(ies) available for trehalose and Alzheimer Disease

ArticleYear
Effect of Trehalose and Ceftriaxone on the Stability of Aggregating-Prone Tau Peptide Containing PHF6* Sequence: An SRCD Study.
    International journal of molecular sciences, 2022, Mar-08, Volume: 23, Issue:6

    Topics: Alzheimer Disease; Ceftriaxone; Circular Dichroism; Humans; Neurofibrillary Tangles; Peptides; Repressor Proteins; Synchrotrons; tau Proteins; Trehalose

2022
Combined induction of mTOR-dependent and mTOR-independent pathways of autophagy activation as an experimental therapy for Alzheimer's disease-like pathology in a mouse model.
    Pharmacology, biochemistry, and behavior, 2022, Volume: 217

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Autophagy; Disease Models, Animal; Mice; Mice, Transgenic; Sirolimus; Therapies, Investigational; TOR Serine-Threonine Kinases; Trehalose

2022
Trehalose Inhibits Aβ Generation and Plaque Formation in Alzheimer's Disease.
    Molecular neurobiology, 2020, Volume: 57, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Disease Models, Animal; Mice; Mice, Transgenic; Plaque, Amyloid; Trehalose

2020
Trehalose against Alzheimer's Disease: Insights into a Potential Therapy.
    BioEssays : news and reviews in molecular, cellular and developmental biology, 2020, Volume: 42, Issue:8

    Topics: Alzheimer Disease; Autophagy; Humans; Proteins; Trehalose

2020
Trehalose Improves Cognition in the Transgenic Tg2576 Mouse Model of Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2017, Volume: 60, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Cognition Disorders; Disease Models, Animal; Green Fluorescent Proteins; Humans; Laser Therapy; Mass Spectrometry; Maze Learning; Metals; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Neuroprotective Agents; Presenilin-1; Recombinant Fusion Proteins; Trehalose

2017
Trehalose rescues Alzheimer's disease phenotypes in APP/PS1 transgenic mice.
    The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:12

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroprotective Agents; Phenotype; Presenilin-1; Trehalose

2013
BAG3 facilitates the clearance of endogenous tau in primary neurons.
    Neurobiology of aging, 2015, Volume: 36, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Alzheimer Disease; Animals; Apoptosis Regulatory Proteins; Autophagy; Cells, Cultured; Molecular Targeted Therapy; Neurons; Proteasome Endopeptidase Complex; Proteolysis; Rats; tau Proteins; Trehalose; Up-Regulation

2015
Non-invasive screening for Alzheimer's disease by sensing salivary sugar using Drosophila cells expressing gustatory receptor (Gr5a) immobilized on an extended gate ion-sensitive field-effect transistor (EG-ISFET) biosensor.
    PloS one, 2015, Volume: 10, Issue:2

    Topics: Aged; Alzheimer Disease; Animals; Biomarkers; Biosensing Techniques; Carbohydrate Metabolism; Case-Control Studies; Cell Line; Drosophila Proteins; Female; Gene Expression; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Receptors, Cell Surface; Saliva; Sensitivity and Specificity; Trehalose

2015
Trehalose Alters Subcellular Trafficking and the Metabolism of the Alzheimer-associated Amyloid Precursor Protein.
    The Journal of biological chemistry, 2016, May-13, Volume: 291, Issue:20

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Autophagy; Cell Line; HEK293 Cells; Hep G2 Cells; Humans; Lysosomes; Mice; Peptide Fragments; Protein Transport; Proteolysis; Subcellular Fractions; TOR Serine-Threonine Kinases; Trehalose

2016
Insulin-degrading enzyme antagonizes insulin-dependent tissue growth and Abeta-induced neurotoxicity in Drosophila.
    FEBS letters, 2010, Jul-02, Volume: 584, Issue:13

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Body Weight; Disease Models, Animal; Drosophila; Female; Glucose; Hemolymph; Humans; Insulysin; Male; Neurons; Trehalose

2010
Effect of trehalose on the interaction of Alzheimer's Aβ-peptide and anionic lipid monolayers.
    Biochimica et biophysica acta, 2011, Volume: 1808, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anions; Computer Simulation; Humans; Lipid Bilayers; Mice; Models, Molecular; Molecular Conformation; Peptides; Phosphatidylglycerols; Temperature; Time Factors; Trehalose

2011
Autophagic degradation of tau in primary neurons and its enhancement by trehalose.
    Neurobiology of aging, 2012, Volume: 33, Issue:10

    Topics: Alzheimer Disease; Animals; Autophagy; Cells, Cultured; Mice; Neurons; Phosphorylation; Rats; tau Proteins; Trehalose

2012
Trehalose protects from aggravation of amyloid pathology induced by isoflurane anesthesia in APP(swe) mutant mice.
    Current Alzheimer research, 2012, Volume: 9, Issue:3

    Topics: Alzheimer Disease; Anesthetics, Inhalation; Animals; Disease Models, Animal; Female; Humans; Isoflurane; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroprotective Agents; Plaque, Amyloid; Treatment Outcome; Trehalose

2012
Trehalose differentially inhibits aggregation and neurotoxicity of beta-amyloid 40 and 42.
    Neurobiology of disease, 2005, Volume: 20, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Cell Line, Tumor; Cytoprotection; Humans; Neuroprotective Agents; Neurotoxins; Peptide Fragments; Plaque, Amyloid; Polymers; Protein Folding; Solubility; Trehalose

2005