trehalose has been researched along with Akinetic-Rigid Variant of Huntington Disease in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (53.85) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Aravindan, S; Chen, KY; Chen, S; Choudhry, H; Liu, AYC; Molfetta, C | 1 |
| Debnath, K; Jana, NR; Pradhan, N; Singh, BK | 1 |
| Casarejos, MJ; de Yebenes, JG; Fernandez-Estevez, MA; Garcia Caldentey, J; Gomez, A; López Sendon, J; Mena, MA; Perucho, J; Ruiz, C | 1 |
| Cortes, CJ; La Spada, AR | 1 |
| Lin, F; Qin, ZH | 1 |
| Casarejos, MJ; de Yébenes, JG; Gómez, A; Mena, MÁ; Muñoz, MP; Perucho, J | 1 |
| Rubinsztein, DC; Sarkar, S | 1 |
| Yang, CR; Yu, RK | 1 |
| Doi, H; Ikeda, T; Jana, NR; Kurosawa, M; Machida, Y; Nekooki, M; Niu, S; Nukina, N; Tanaka, M | 1 |
| Adachi, H; Katsuno, M; Sobue, G | 1 |
| Couzin, J | 1 |
| Machida, Y; Nukina, N; Tanaka, M | 1 |
| Davies, JE; Huang, Z; Rubinsztein, DC; Sarkar, S; Tunnacliffe, A | 1 |
4 review(s) available for trehalose and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
The many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapy.
Topics: Animals; Autophagy; Endoplasmic Reticulum Stress; Humans; Huntingtin Protein; Huntington Disease; Nerve Tissue Proteins; Sirolimus; Trehalose | 2014 |
Degradation of misfolded proteins by autophagy: is it a strategy for Huntington's disease treatment?
Topics: Autophagy; Carbamazepine; Humans; Huntingtin Protein; Huntington Disease; Lithium; Mutant Proteins; Nerve Tissue Proteins; Oxazoles; Peptides; Rilmenidine; Sirolimus; Trehalose; Trinucleotide Repeat Expansion; Valproic Acid | 2013 |
Huntington's disease: degradation of mutant huntingtin by autophagy.
Topics: Autophagy; Humans; Huntingtin Protein; Huntington Disease; Inositol; Lithium Compounds; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Protein Kinases; Sirolimus; TOR Serine-Threonine Kinases; Trehalose | 2008 |
A novel therapeutic strategy for polyglutamine diseases by stabilizing aggregation-prone proteins with small molecules.
Topics: Amyloid; Animals; Disease Models, Animal; Forecasting; Humans; Huntington Disease; Models, Biological; Peptides; Trehalose | 2005 |
9 other study(ies) available for trehalose and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Osmolytes dynamically regulate mutant Huntingtin aggregation and CREB function in Huntington's disease cell models.
Topics: Animals; Autophagy; Cyclic AMP Response Element-Binding Protein; Gene Knockdown Techniques; Glycerol; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Huntingtin Protein; Huntington Disease; Mutation; Osmolar Concentration; PC12 Cells; Protein Aggregation, Pathological; Protein Folding; Rats; Sorbitol; Sucrose; Trehalose | 2020 |
Poly(trehalose) Nanoparticles Prevent Amyloid Aggregation and Suppress Polyglutamine Aggregation in a Huntington's Disease Model Mouse.
Topics: Animals; Huntington Disease; Mice; Nanoparticles; Nerve Tissue Proteins; Peptides; Trehalose | 2017 |
Trehalose reverses cell malfunction in fibroblasts from normal and Huntington's disease patients caused by proteosome inhibition.
Topics: Apoptosis; Autophagy; Cell Survival; Fibroblasts; HSP70 Heat-Shock Proteins; Humans; Huntington Disease; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Reactive Oxygen Species; Trehalose; Ubiquitination | 2014 |
Trehalose rescues glial cell dysfunction in striatal cultures from HD R6/1 mice at early postnatal development.
Topics: alpha-Synuclein; Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Corpus Striatum; Cytoskeleton; Female; Glial Cell Line-Derived Neurotrophic Factor; Gliosis; Humans; Huntingtin Protein; Huntington Disease; Male; Mice; Mice, Inbred C57BL; Neuroglia; Neuroprotective Agents; Protein Transport; Trehalose | 2016 |
Intracerebral transplantation of neural stem cells combined with trehalose ingestion alleviates pathology in a mouse model of Huntington's disease.
Topics: Administration, Oral; Analysis of Variance; Animals; Body Weight; Corpus Striatum; Disease Models, Animal; Hand Strength; Humans; Huntingtin Protein; Huntington Disease; Maze Learning; Mice; Mice, Transgenic; Microarray Analysis; Motor Activity; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Peptides; Psychomotor Performance; Stem Cell Transplantation; Survival Analysis; Trehalose; Trinucleotide Repeat Expansion | 2009 |
Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease.
Topics: Animals; Brain; Cell Death; Cell Line; Disease Models, Animal; Glucose; Humans; Huntingtin Protein; Huntington Disease; Liver; Mice; Mice, Transgenic; Motor Activity; Myoglobin; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Peptides; Trehalose | 2004 |
Sweet relief for Huntington disease.
Topics: Animals; Disease Models, Animal; Humans; Huntington Disease; Mice; Mice, Transgenic; Peptides; Trehalose | 2004 |
Huntington's disease. Unorthodox clinical trials meld science and care.
Topics: Animals; Blueberry Plants; Clinical Trials as Topic; Creatine; Cysteamine; Drug Therapy, Combination; Drug Therapy, Computer-Assisted; Fatty Acids, Omega-3; Humans; Huntington Disease; Mice; Patient Selection; Phytotherapy; Plant Extracts; Software; Trehalose; Ubiquinone | 2004 |
Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.
Topics: alpha-Synuclein; Animals; Antibiotics, Antineoplastic; Autophagy; Chlorocebus aethiops; COS Cells; HeLa Cells; Humans; Huntingtin Protein; Huntington Disease; Mice; Molecular Chaperones; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Parkinson Disease; Protein Kinases; Sirolimus; TOR Serine-Threonine Kinases; Trehalose | 2007 |