Page last updated: 2024-11-05

trazodone and Xerostomia

trazodone has been researched along with Xerostomia in 4 studies

Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.

Xerostomia: Decreased salivary flow.

Research Excerpts

ExcerptRelevanceReference
"An analysis was made of the occurrence of anticholinergic side effects in 15 multicenter studies of 379 patients with endogenous depression who received either trazodone, imipramine, or placebo."3.66Lack of anticholinergic side effects with a new antidepressent--trazodone. ( Gershon, S; Newton, R, 1980)
"Trazodone was less troublesome in respect of the persistent dry mouth and severe adverse psychiatric reactions which occurred with amitriptyline."2.65Trazodone. A comparative clinical and predictive study. ( Ankier, SI; Kerr, TA; McClelland, HA; Stephens, DA, 1984)
" The injury appears as glandular swellings and/or decreased salivation with 131I dosage and passage of time playing significant roles."1.34False-positive xerostomia following radioactive iodine treatment: case report. ( Mandel, L; Mandel, SJ, 2007)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mandel, SJ1
Mandel, L1
Kerr, TA1
McClelland, HA1
Stephens, DA1
Ankier, SI1
Henry, JA1
Ali, CJ1
Caldwell, R1
Flanagan, RJ1
Gershon, S1
Newton, R1

Trials

1 trial available for trazodone and Xerostomia

ArticleYear
Trazodone. A comparative clinical and predictive study.
    Acta psychiatrica Scandinavica, 1984, Volume: 70, Issue:6

    Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Male; Mid

1984

Other Studies

3 other studies available for trazodone and Xerostomia

ArticleYear
False-positive xerostomia following radioactive iodine treatment: case report.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2007, Volume: 103, Issue:2

    Topics: Adult; Antidepressive Agents, Second-Generation; Diagnosis, Differential; False Positive Reactions;

2007
Acute trazodone poisoning: clinical signs and plasma concentrations.
    Psychopathology, 1984, Volume: 17 Suppl 2

    Topics: Adolescent; Adult; Ataxia; Child; Coma; Dose-Response Relationship, Drug; Female; Humans; Male; Midd

1984
Lack of anticholinergic side effects with a new antidepressent--trazodone.
    The Journal of clinical psychiatry, 1980, Volume: 41, Issue:3

    Topics: Adult; Aged; Constipation; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; Middle

1980