trazodone has been researched along with Xerostomia in 4 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
Xerostomia: Decreased salivary flow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An analysis was made of the occurrence of anticholinergic side effects in 15 multicenter studies of 379 patients with endogenous depression who received either trazodone, imipramine, or placebo." | 3.66 | Lack of anticholinergic side effects with a new antidepressent--trazodone. ( Gershon, S; Newton, R, 1980) |
| "Trazodone was less troublesome in respect of the persistent dry mouth and severe adverse psychiatric reactions which occurred with amitriptyline." | 2.65 | Trazodone. A comparative clinical and predictive study. ( Ankier, SI; Kerr, TA; McClelland, HA; Stephens, DA, 1984) |
| " The injury appears as glandular swellings and/or decreased salivation with 131I dosage and passage of time playing significant roles." | 1.34 | False-positive xerostomia following radioactive iodine treatment: case report. ( Mandel, L; Mandel, SJ, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mandel, SJ | 1 |
| Mandel, L | 1 |
| Kerr, TA | 1 |
| McClelland, HA | 1 |
| Stephens, DA | 1 |
| Ankier, SI | 1 |
| Henry, JA | 1 |
| Ali, CJ | 1 |
| Caldwell, R | 1 |
| Flanagan, RJ | 1 |
| Gershon, S | 1 |
| Newton, R | 1 |
1 trial available for trazodone and Xerostomia
| Article | Year |
|---|---|
Trazodone. A comparative clinical and predictive study.
Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Male; Mid | 1984 |
3 other studies available for trazodone and Xerostomia
| Article | Year |
|---|---|
False-positive xerostomia following radioactive iodine treatment: case report.
Topics: Adult; Antidepressive Agents, Second-Generation; Diagnosis, Differential; False Positive Reactions; | 2007 |
Acute trazodone poisoning: clinical signs and plasma concentrations.
Topics: Adolescent; Adult; Ataxia; Child; Coma; Dose-Response Relationship, Drug; Female; Humans; Male; Midd | 1984 |
Lack of anticholinergic side effects with a new antidepressent--trazodone.
Topics: Adult; Aged; Constipation; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; Middle | 1980 |