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trazodone and Tremor

trazodone has been researched along with Tremor in 12 studies

Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
"Accelerometric tremorgrams were recorded from 25 subjects affected by essential tremor and analysed by a Berg-Fourier frequency analyser before and during venous infusion of the following drugs: propranolol (beta-blocker), clonidine (alpha-presynaptic adrenergic agonist), urapidil (alpha-postsynaptic blocker), trazodone (adrenolytic agent) and placebo."9.06Propranolol, clonidine, urapidil and trazodone infusion in essential tremor: a double-blind crossover trial. ( Caccia, MR; Cataldi, G; Galimberti, V; Mangoni, A; Osio, M, 1989)
"Phenoxybenzamine (5 mg/kg IP) and trazodone (5 mg/kg IP) reduced tremors produced in mice by administration of oxotremorine (10 mg/kg), harmaline (80 mg/kg), catechol (60 mg/kg), kepone (200 mg/kg) and clonidine (100 mg/kg)."7.66Serotonin-norepinephrine interactions in the tremorolytic actions of phenoxybenzamine and trazodone. ( Hwang, EC; van Woert, MH, 1979)
" For individual adverse events that developed or worsened during therapy, more fluoxetine-treated patients reported rhinitis and tremor (p less than or equal to ."5.07Fluoxetine versus trazodone: efficacy and activating-sedating effects. ( Beasley, CM; Bosomworth, JC; Dornseif, BE; Pultz, JA; Sayler, ME, 1991)
"Accelerometric tremorgrams were recorded from 25 subjects affected by essential tremor and analysed by a Berg-Fourier frequency analyser before and during venous infusion of the following drugs: propranolol (beta-blocker), clonidine (alpha-presynaptic adrenergic agonist), urapidil (alpha-postsynaptic blocker), trazodone (adrenolytic agent) and placebo."5.06Propranolol, clonidine, urapidil and trazodone infusion in essential tremor: a double-blind crossover trial. ( Caccia, MR; Cataldi, G; Galimberti, V; Mangoni, A; Osio, M, 1989)
"Phenoxybenzamine (5 mg/kg IP) and trazodone (5 mg/kg IP) reduced tremors produced in mice by administration of oxotremorine (10 mg/kg), harmaline (80 mg/kg), catechol (60 mg/kg), kepone (200 mg/kg) and clonidine (100 mg/kg)."3.66Serotonin-norepinephrine interactions in the tremorolytic actions of phenoxybenzamine and trazodone. ( Hwang, EC; van Woert, MH, 1979)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's2 (16.67)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Settle, EC1
Pohlmeier, H1
Darko, W1
Guharoy, R1
Rose, F1
Lehman, D1
Pappas, V1
Silvestrini, B1
Lisciani, R1
Hwang, EC1
van Woert, MH1
Fedeli, S1
Ferri, FA1
Fogari, R1
Karniol, IG1
Dalton, J1
Lader, M1
Beasley, CM1
Dornseif, BE1
Pultz, JA1
Bosomworth, JC1
Sayler, ME1
Cleeves, L1
Findley, LJ1
Koller, WC1
Caccia, MR1
Osio, M1
Galimberti, V1
Cataldi, G1
Mangoni, A1
McLeod, NA1
White, LE1

Trials

5 trials available for trazodone and Tremor

ArticleYear
Blockade of acute opiate-withdrawal symptoms by trazodone treatment.
    Bollettino chimico farmaceutico, 1979, Volume: 118, Issue:7

    Topics: Acute Disease; Anxiety; Clinical Trials as Topic; Heroin Dependence; Humans; Piperazines; Substance

1979
Fluoxetine versus trazodone: efficacy and activating-sedating effects.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:7

    Topics: Adult; Akathisia, Drug-Induced; Ambulatory Care; Anxiety; Depressive Disorder; Dizziness; Double-Bli

1991
Trazodone is ineffective in essential tremor.
    Journal of neurology, neurosurgery, and psychiatry, 1990, Volume: 53, Issue:3

    Topics: Adult; Aged; Double-Blind Method; Humans; Middle Aged; Neurologic Examination; Randomized Controlled

1990
Tradozone in essential tremor. Probe of serotoninergic mechanisms.
    Clinical neuropharmacology, 1989, Volume: 12, Issue:2

    Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Male; Middle Aged; Random Allocation; Recepto

1989
Propranolol, clonidine, urapidil and trazodone infusion in essential tremor: a double-blind crossover trial.
    Acta neurologica Scandinavica, 1989, Volume: 79, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Clonidine; Double-Blind Method; Female; Humans; Injections, Intraven

1989

Other Studies

7 other studies available for trazodone and Tremor

ArticleYear
Recently introduced antidepressants: their place in clinical practice.
    Postgraduate medicine, 1982, Volume: 72, Issue:3

    Topics: Amoxapine; Antidepressive Agents; Bundle of His; Chemical Phenomena; Chemistry; Depressive Disorder;

1982
[Contribution to a discussion on the importance of the non-tricyclic antidepressives for the development of a theory of depression (author's transl)].
    Pharmacopsychiatria, 1981, Volume: 14, Issue:2

    Topics: Antidepressive Agents; Depressive Disorder; Humans; Middle Aged; Trazodone; Tremor

1981
Myoclonus secondary to the concurrent use of trazodone and fluoxetine.
    Veterinary and human toxicology, 2001, Volume: 43, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Depression; Drug Synergism; Fluoxetine; HIV Infecti

2001
Experimental data suggesting an adrenergic mechanism in the production of parkinsonian symptoms.
    Current therapeutic research, clinical and experimental, 1976, Volume: 20, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Clonidine; Female; Fenclonine; Imipramine; Male; Mice; Mice,

1976
Serotonin-norepinephrine interactions in the tremorolytic actions of phenoxybenzamine and trazodone.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Male; Mice; Norepinephrine; Phenoxybenzamine; Piperazines; Serotonin;

1979
Comparative psychotropic effects of trazodone, imipramine and diazepam in normal subjects.
    Current therapeutic research, clinical and experimental, 1976, Volume: 20, Issue:3

    Topics: Acoustic Stimulation; Adult; Blood Pressure; Diazepam; Dose-Response Relationship, Drug; Evoked Pote

1976
Trazodone in essential tremor.
    JAMA, 1986, Nov-21, Volume: 256, Issue:19

    Topics: Aged; Humans; Male; Middle Aged; Trazodone; Tremor

1986