Page last updated: 2024-11-05

trazodone and Stroke

trazodone has been researched along with Stroke in 3 studies

Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to compare the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression."9.69Comparison of the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression. ( Cui, Q; Wei, W, 2023)
"Obstructive sleep apnea with comorbid ischemic stroke may be a distinctive phenotype which responds quite well to trazodone, decreasing OSA severity without increasing nocturnal hypoxia."9.41Trazodone improves obstructive sleep apnea after ischemic stroke: a randomized, double-blind, placebo-controlled, crossover pilot study. ( Chen, CL; Chen, CY; Yu, CC, 2021)
"The purpose of this study was to compare the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression."5.69Comparison of the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression. ( Cui, Q; Wei, W, 2023)
"Obstructive sleep apnea with comorbid ischemic stroke may be a distinctive phenotype which responds quite well to trazodone, decreasing OSA severity without increasing nocturnal hypoxia."5.41Trazodone improves obstructive sleep apnea after ischemic stroke: a randomized, double-blind, placebo-controlled, crossover pilot study. ( Chen, CL; Chen, CY; Yu, CC, 2021)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Cui, Q1
Wei, W1
Chen, CY1
Chen, CL1
Yu, CC1
Morinaga, Y1
Nii, K1
Sakamoto, K1
Inoue, R1
Mitsutake, T1
Hanada, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Trazodone on the Severity of Obstructive Sleep Apnea in Insomnic Stroke Patients With Depression[NCT04162743]Phase 422 participants (Actual)Interventional2019-02-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for trazodone and Stroke

ArticleYear
Comparison of the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression.
    JPMA. The Journal of the Pakistan Medical Association, 2023, Volume: 73, Issue:4

    Topics: Brain-Derived Neurotrophic Factor; Depression; Humans; Needles; Serotonin; Stroke; Tablets; Trazodon

2023
Trazodone improves obstructive sleep apnea after ischemic stroke: a randomized, double-blind, placebo-controlled, crossover pilot study.
    Journal of neurology, 2021, Volume: 268, Issue:8

    Topics: Aged; Blood Pressure Monitoring, Ambulatory; Brain Ischemia; Cross-Over Studies; Double-Blind Method

2021

Other Studies

1 other study available for trazodone and Stroke

ArticleYear
Efficacy of trazodone for treating paroxysmal sympathetic hyperactivity presenting after thalamic hemorrhage: A case report.
    Drug discoveries & therapeutics, 2019, Volume: 13, Issue:3

    Topics: Autonomic Nervous System Diseases; Female; Humans; Intracranial Hemorrhages; Japan; Middle Aged; Str

2019