trazodone has been researched along with Stroke in 3 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to compare the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression." | 9.69 | Comparison of the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression. ( Cui, Q; Wei, W, 2023) |
| "Obstructive sleep apnea with comorbid ischemic stroke may be a distinctive phenotype which responds quite well to trazodone, decreasing OSA severity without increasing nocturnal hypoxia." | 9.41 | Trazodone improves obstructive sleep apnea after ischemic stroke: a randomized, double-blind, placebo-controlled, crossover pilot study. ( Chen, CL; Chen, CY; Yu, CC, 2021) |
| "The purpose of this study was to compare the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression." | 5.69 | Comparison of the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression. ( Cui, Q; Wei, W, 2023) |
| "Obstructive sleep apnea with comorbid ischemic stroke may be a distinctive phenotype which responds quite well to trazodone, decreasing OSA severity without increasing nocturnal hypoxia." | 5.41 | Trazodone improves obstructive sleep apnea after ischemic stroke: a randomized, double-blind, placebo-controlled, crossover pilot study. ( Chen, CL; Chen, CY; Yu, CC, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, Q | 1 |
| Wei, W | 1 |
| Chen, CY | 1 |
| Chen, CL | 1 |
| Yu, CC | 1 |
| Morinaga, Y | 1 |
| Nii, K | 1 |
| Sakamoto, K | 1 |
| Inoue, R | 1 |
| Mitsutake, T | 1 |
| Hanada, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Trazodone on the Severity of Obstructive Sleep Apnea in Insomnic Stroke Patients With Depression[NCT04162743] | Phase 4 | 22 participants (Actual) | Interventional | 2019-02-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for trazodone and Stroke
| Article | Year |
|---|---|
Comparison of the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression.
Topics: Brain-Derived Neurotrophic Factor; Depression; Humans; Needles; Serotonin; Stroke; Tablets; Trazodon | 2023 |
Trazodone improves obstructive sleep apnea after ischemic stroke: a randomized, double-blind, placebo-controlled, crossover pilot study.
Topics: Aged; Blood Pressure Monitoring, Ambulatory; Brain Ischemia; Cross-Over Studies; Double-Blind Method | 2021 |
1 other study available for trazodone and Stroke
| Article | Year |
|---|---|
Efficacy of trazodone for treating paroxysmal sympathetic hyperactivity presenting after thalamic hemorrhage: A case report.
Topics: Autonomic Nervous System Diseases; Female; Humans; Intracranial Hemorrhages; Japan; Middle Aged; Str | 2019 |