Page last updated: 2024-11-05

trazodone and Psychotic Disorders

trazodone has been researched along with Psychotic Disorders in 7 studies

Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.

Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)

Research Excerpts

ExcerptRelevanceReference
"Randomized, controlled trials of antidepressants (selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants, trazodone, and other antidepressants), compared to either placebo or comparator medications (typical or atypical antipsychotics, anticonvulsants, benzodiazepines, cholinesterase inhibitors, memantine or other medications) for treatment of agitation or psychosis in older adults with dementia."4.87Antidepressants for agitation and psychosis in dementia. ( Adunuri, N; Gill, SS; Gruneir, A; Herrmann, N; Rochon, P; Seitz, DP, 2011)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (57.14)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Seitz, DP1
Adunuri, N1
Gill, SS1
Gruneir, A1
Herrmann, N1
Rochon, P1
Ribosa-Nogué, R1
Pagonabarraga, J1
Kulisevsky, J1
Fernandez, F1
Levy, JK1
Tariot, PN1
Lawlor, B1
Sultzer, DL1
Gray, KF1
Gunay, I1
Wheatley, MV1
Mahler, ME1
Jacobsen, FM1

Reviews

3 reviews available for trazodone and Psychotic Disorders

ArticleYear
Antidepressants for agitation and psychosis in dementia.
    The Cochrane database of systematic reviews, 2011, Feb-16, Issue:2

    Topics: Adult; Antidepressive Agents; Citalopram; Dementia; Humans; Psychomotor Agitation; Psychotic Disorde

2011
Psychopharmacology in HIV spectrum disorders.
    The Psychiatric clinics of North America, 1994, Volume: 17, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; Anti-Anxiety Agents; Antipsychotic Agents

1994
Treatment strategies for agitation and psychosis in dementia.
    The Journal of clinical psychiatry, 1996, Volume: 57 Suppl 14

    Topics: Aged; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Clozapine;

1996

Trials

1 trial available for trazodone and Psychotic Disorders

ArticleYear
Does behavioral improvement with haloperidol or trazodone treatment depend on psychosis or mood symptoms in patients with dementia?
    Journal of the American Geriatrics Society, 2001, Volume: 49, Issue:10

    Topics: Aged; Alzheimer Disease; Analysis of Variance; Antidepressive Agents, Second-Generation; Antipsychot

2001

Other Studies

3 other studies available for trazodone and Psychotic Disorders

ArticleYear
Efficacy of trazodone in antipsychotic-induced akathisia resistant to conventional treatment.
    Parkinsonism & related disorders, 2012, Volume: 18, Issue:7

    Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Female; Follow-Up Studies; Humans; Middle Aged; Psych

2012
'The use of selective serotonin reuptake inhibitors for depression and psychosis complicating dementia'--1997, 12, 519-527.
    International journal of geriatric psychiatry, 1998, Volume: 13, Issue:7

    Topics: Buspirone; Dementia; Depression; Drug Therapy, Combination; Humans; Psychotic Disorders; Selective S

1998
Low-dose trazodone as a hypnotic in patients treated with MAOIs and other psychotropics: a pilot study.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:7

    Topics: Administration, Oral; Adult; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Middle Age

1990