trazodone has been researched along with Neuralgia in 4 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neuropathic pain is a chronic debilitating condition caused by injury or disease of the nerves of the somatosensory system." | 1.62 | Synergistic interaction between trazodone and gabapentin in rodent models of neuropathic pain. ( Amato, A; Di Giorgio, FP; di Matteo, A; Durando, L; Garrone, B; Milanese, C; Pistillo, L; Tongiani, S, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oggianu, L | 1 |
| Garrone, B | 2 |
| Fiorentini, F | 1 |
| Del Bene, F | 1 |
| Rosignoli, MT | 1 |
| Di Giorgio, FP | 2 |
| Kaminski, RM | 1 |
| di Matteo, A | 1 |
| Amato, A | 1 |
| Pistillo, L | 1 |
| Durando, L | 1 |
| Milanese, C | 1 |
| Tongiani, S | 1 |
| Ventafridda, V | 2 |
| Caraceni, A | 2 |
| Saita, L | 2 |
| Bonezzi, C | 2 |
| De Conno, F | 2 |
| Guarise, G | 2 |
| Ramella, G | 2 |
| Silvani, V | 2 |
| Tamburini, M | 2 |
| Toscani, F | 2 |
2 trials available for trazodone and Neuralgia
| Article | Year |
|---|---|
Trazodone for deafferentation pain. Comparison with amitriptyline.
Topics: Adult; Afferent Pathways; Aged; Amitriptyline; Clinical Trials as Topic; Double-Blind Method; Humans | 1988 |
Antidepressants for cancer pain and other painful syndromes with deafferentation component: comparison of amitriptyline and trazodone.
Topics: Adult; Aged; Amitriptyline; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Humans; | 1987 |
2 other studies available for trazodone and Neuralgia
| Article | Year |
|---|---|
PK/PD analysis of trazodone and gabapentin in neuropathic pain rodent models: Translational PK-PD modeling from nonclinical to clinical development.
Topics: Acetic Acid; Analgesics; Animals; Gabapentin; Humans; Mice; Models, Biological; Neuralgia; Rodentia; | 2023 |
Synergistic interaction between trazodone and gabapentin in rodent models of neuropathic pain.
Topics: Analgesics; Animals; Anti-Anxiety Agents; Depressive Disorder, Major; Disease Models, Animal; Drug S | 2021 |