Page last updated: 2024-11-05

trazodone and Nerve Pain

trazodone has been researched along with Nerve Pain in 4 studies

Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.

Research Excerpts

ExcerptRelevanceReference
"Neuropathic pain is a chronic debilitating condition caused by injury or disease of the nerves of the somatosensory system."1.62Synergistic interaction between trazodone and gabapentin in rodent models of neuropathic pain. ( Amato, A; Di Giorgio, FP; di Matteo, A; Durando, L; Garrone, B; Milanese, C; Pistillo, L; Tongiani, S, 2021)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Oggianu, L1
Garrone, B2
Fiorentini, F1
Del Bene, F1
Rosignoli, MT1
Di Giorgio, FP2
Kaminski, RM1
di Matteo, A1
Amato, A1
Pistillo, L1
Durando, L1
Milanese, C1
Tongiani, S1
Ventafridda, V2
Caraceni, A2
Saita, L2
Bonezzi, C2
De Conno, F2
Guarise, G2
Ramella, G2
Silvani, V2
Tamburini, M2
Toscani, F2

Trials

2 trials available for trazodone and Nerve Pain

ArticleYear
Trazodone for deafferentation pain. Comparison with amitriptyline.
    Psychopharmacology, 1988, Volume: 95 Suppl

    Topics: Adult; Afferent Pathways; Aged; Amitriptyline; Clinical Trials as Topic; Double-Blind Method; Humans

1988
Antidepressants for cancer pain and other painful syndromes with deafferentation component: comparison of amitriptyline and trazodone.
    Italian journal of neurological sciences, 1987, Volume: 8, Issue:6

    Topics: Adult; Aged; Amitriptyline; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Humans;

1987

Other Studies

2 other studies available for trazodone and Nerve Pain

ArticleYear
PK/PD analysis of trazodone and gabapentin in neuropathic pain rodent models: Translational PK-PD modeling from nonclinical to clinical development.
    Clinical and translational science, 2023, Volume: 16, Issue:4

    Topics: Acetic Acid; Analgesics; Animals; Gabapentin; Humans; Mice; Models, Biological; Neuralgia; Rodentia;

2023
Synergistic interaction between trazodone and gabapentin in rodent models of neuropathic pain.
    PloS one, 2021, Volume: 16, Issue:1

    Topics: Analgesics; Animals; Anti-Anxiety Agents; Depressive Disorder, Major; Disease Models, Animal; Drug S

2021