Page last updated: 2024-11-05

trazodone and Muscle Contraction

trazodone has been researched along with Muscle Contraction in 10 studies

Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"Both imipramine and trazodone were utilized as standards representing typical and atypical antidepressant drugs, respectively."1.27Antihistamine, anticholinergic and cardiovascular effects of 2-substituted-4-phenylquinoline derivatives. ( Alhaider, AA, 1986)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19906 (60.00)18.7374
1990's3 (30.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shen, KP1
Liou, SF1
Hsieh, SL1
Chen, IJ1
Wu, BN1
Wrigglesworth, SJ1
Alvarez, FJ1
Carvajal, A1
Dueñas, A1
González, JL1
Velasco Martín, A1
Alhaider, AA2
Chiang, PH1
Tsai, EM1
Chiang, CP1
Pescatori, ES1
Engelman, JC1
Davis, G1
Goldstein, I1
Galzigna, L1
Manani, G1
Bianchi, M1
Pittoni, G1
Bossi, M1
Giron, GP1
Przegaliński, E1
Lewandowska, A1
Clouse, RE1
Lustman, PJ1
Eckert, TC1
Ferney, DM1
Griffith, LS1

Trials

2 trials available for trazodone and Muscle Contraction

ArticleYear
The role of trazodone in the treatment of erectile dysfunction.
    Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences, 1994, Volume: 10, Issue:6

    Topics: Adult; Aged; Animals; Erectile Dysfunction; Humans; In Vitro Techniques; Male; Middle Aged; Muscle C

1994
Low-dose trazodone for symptomatic patients with esophageal contraction abnormalities. A double-blind, placebo-controlled trial.
    Gastroenterology, 1987, Volume: 92, Issue:4

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Esophageal Diseases; Esophag

1987

Other Studies

8 other studies available for trazodone and Muscle Contraction

ArticleYear
Eugenosedin-A amelioration of lipopolysaccharide-induced up-regulation of p38 MAPK, inducible nitric oxide synthase and cyclooxygenase-2.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Antioxidants; Aorta, Thoracic; Ascorbic Acid; Blotting, Weste

2007
Heterogeneity of 5-hydroxytryptamine receptors in the rat uterus and stomach strip.
    British journal of pharmacology, 1983, Volume: 80, Issue:4

    Topics: Amitriptyline; Animals; Female; In Vitro Techniques; Male; Methysergide; Muscle Contraction; Muscle,

1983
[Comparative analysis of trazodone and imipramine against acetylcholine and electrical stimulation in the isolated guinea pig ileum].
    Archivos de farmacologia y toxicologia, 1983, Volume: 9, Issue:3

    Topics: Acetylcholine; Animals; Electric Stimulation; Female; Guinea Pigs; Ileum; Imipramine; Male; Muscle C

1983
Anticholinergic, antihistaminic and cardiovascular effects of two new congeners of quipazine and trazodone.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:11

    Topics: Animals; Blood Pressure; Cardiovascular Agents; Electrocardiography; Female; Guinea Pigs; Histamine

1993
Priapism of the clitoris: a case report following trazodone use.
    The Journal of urology, 1993, Volume: 149, Issue:6

    Topics: Adjustment Disorders; Adult; Clitoris; Depression; Female; Fluoxetine; Humans; Muscle Contraction; M

1993
Some experimental effects with trazodone.
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1979, Volume: 20, Issue:4

    Topics: Animals; Male; Microsomes, Liver; Mixed Function Oxygenases; Muscle Contraction; Piperazines; Rabbit

1979
The effect of etoperidone, a new potential antidepressant drug, on the central serotonin system.
    Journal of neural transmission, 1979, Volume: 46, Issue:4

    Topics: Animals; Antidepressive Agents; Male; Mice; Movement; Muscle Contraction; Piperazines; Rats; Reflex;

1979
Antihistamine, anticholinergic and cardiovascular effects of 2-substituted-4-phenylquinoline derivatives.
    Life sciences, 1986, Feb-17, Volume: 38, Issue:7

    Topics: Acetylcholine; Animals; Body Temperature; Cardiovascular System; Electrocardiography; Guinea Pigs; H

1986