Page last updated: 2024-11-05

trazodone and Morphine Abuse

trazodone has been researched along with Morphine Abuse in 3 studies

Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.

Research Excerpts

ExcerptRelevanceReference
"Intensity of withdrawal symptoms was evaluated by tail-flick assay latencies and three behavioural measurements (rearing, jumping and grooming) in each group."1.32Mianserin and trazodone significantly attenuate the intensity of opioid withdrawal symptoms in mice. ( Backler, MM; Bar-Hamburger, R; Herman, I; Pick, CG; Rigai, T; Schreiber, S; Shamir, D, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schreiber, S1
Backler, MM1
Herman, I1
Shamir, D1
Rigai, T1
Bar-Hamburger, R1
Pick, CG1
Cervo, L1
Ballabio, M1
Caccia, S1
Samanin, R1
Valeri, P1
Pimpinella, G1
Troiani, MP1
Morrone, LA1
Romanelli, L1

Other Studies

3 other studies available for trazodone and Morphine Abuse

ArticleYear
Mianserin and trazodone significantly attenuate the intensity of opioid withdrawal symptoms in mice.
    Addiction biology, 2003, Volume: 8, Issue:1

    Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Anti-Anxiety Agents; Disease Models, An

2003
Blockade by trazodone of naloxone-precipitated jumping on morphine-dependent rats: correlation with brain levels of m-chlorophenylpiperazine.
    The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:12

    Topics: Animals; Brain; Brain Chemistry; Humans; Male; Morphine Dependence; Motor Activity; Naloxone; Pipera

1981
Effects of trazodone and m-chlorophenylpiperazine (m-CPP) on acute dependence in mice.
    Brain research bulletin, 1991, Volume: 26, Issue:5

    Topics: Acute Disease; Animals; Behavior, Animal; Male; Mice; Morphine Dependence; Piperazines; Receptors, S

1991