trazodone has been researched along with Melanoma in 2 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cinnarizine and trazodone were identified as melanogenesis inhibitors." | 5.37 | Melanogenesis inhibitory activity of two generic drugs: cinnarizine and trazodone in mouse B16 melanoma cells. ( Chang, TS; Lin, VC, 2011) |
| " We report a case of severe protracted depression induced by IFN in a patient diagnosed with melanoma who responded rapidly to a course of methylphenidate using the Hamilton Depressive Rating Scale." | 3.73 | Methylphenidate for alpha-interferon induced depression. ( Camacho, A; Ng, B, 2006) |
| "Cinnarizine and trazodone were identified as melanogenesis inhibitors." | 1.37 | Melanogenesis inhibitory activity of two generic drugs: cinnarizine and trazodone in mouse B16 melanoma cells. ( Chang, TS; Lin, VC, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, TS | 1 |
| Lin, VC | 1 |
| Camacho, A | 1 |
| Ng, B | 1 |
2 other studies available for trazodone and Melanoma
| Article | Year |
|---|---|
Melanogenesis inhibitory activity of two generic drugs: cinnarizine and trazodone in mouse B16 melanoma cells.
Topics: Animals; Cell Line, Tumor; Cinnarizine; Melanins; Melanoma; Mice; Monophenol Monooxygenase; Skin Lig | 2011 |
Methylphenidate for alpha-interferon induced depression.
Topics: Affect; Aged; Antineoplastic Agents; Central Nervous System Stimulants; Depressive Disorder; Humans; | 2006 |