trazodone has been researched along with Hypotension, Orthostatic in 6 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
Hypotension, Orthostatic: A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Severe orthostatic hypotension is more likely to develop in depressed patients with left ventricular impairment and/or in patients taking other drugs like diuretics or vasodilators." | 2.38 | Review of the cardiovascular effects of heterocyclic antidepressants. ( Glassman, AH; Preud'homme, XA, 1993) |
| "Trazodone has emerged as the antidepressant drug with the least risk of death in overdose, and as a useful alternative to the standard tricyclic antidepressant drugs in patients with preexisting conduction disease." | 2.37 | Cardiovascular toxicity of antidepressant medications. ( Glassman, AH; Jackson, WK; Roose, SP, 1987) |
| "Trazodone has been used widely to treat insomnia in depressed patients." | 1.31 | Electroconvulsive therapy and cardiovascular complications in patients taking trazodone for insomnia. ( Hanson, CA; Krahn, LE; Pileggi, TS; Rummans, TA, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tang, C | 1 |
| Yu, R | 1 |
| Glassman, AH | 3 |
| Preud'homme, XA | 1 |
| Krahn, LE | 1 |
| Hanson, CA | 1 |
| Pileggi, TS | 1 |
| Rummans, TA | 1 |
| Jackson, WK | 1 |
| Roose, SP | 1 |
| Spivak, B | 1 |
| Radvan, M | 1 |
| Shine, M | 1 |
2 reviews available for trazodone and Hypotension, Orthostatic
| Article | Year |
|---|---|
Review of the cardiovascular effects of heterocyclic antidepressants.
Topics: Amoxapine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Bupropion; | 1993 |
Cardiovascular toxicity of antidepressant medications.
Topics: Antidepressive Agents; Arrhythmias, Cardiac; Depressive Disorder; Humans; Hypotension, Orthostatic; | 1987 |
4 other studies available for trazodone and Hypotension, Orthostatic
| Article | Year |
|---|---|
Adult-onset idiopathic isolated central hypothyroidism: a case report and literature review.
Topics: Adrenergic alpha-1 Receptor Agonists; Antidepressive Agents, Second-Generation; Depression; Female; | 2015 |
The newer antidepressant drugs and their cardiovascular effects.
Topics: Amoxapine; Antidepressive Agents; Bupropion; Cardiovascular System; Electrocardiography; Humans; Hyp | 1984 |
Electroconvulsive therapy and cardiovascular complications in patients taking trazodone for insomnia.
Topics: Adult; Cardiovascular Diseases; Case-Control Studies; Comorbidity; Confidence Intervals; Depressive | 2001 |
Postural hypotension with syncope possibly precipitated by trazodone.
Topics: Aged; Antihypertensive Agents; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Hypot | 1987 |