Page last updated: 2024-11-05

trazodone and Edema

trazodone has been researched along with Edema in 4 studies

Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
"Ten depressed patients treated with trazodone developed edema and weight gain that was promptly reversed by reduction or discontinuation of trazodone."7.67Peripheral edema associated with trazodone: a report of ten cases. ( Barrnett, J; Brown, R; Frances, A; Kocsis, J; Mann, JJ, 1985)
"The anti-inflammatory activity of fluoxetine, a selective serotonin reuptake inhibitor (SSRI), was studied on the carrageenan-induced paw inflammation in the rat."3.72Studies on the anti-inflammatory effect of fluoxetine in the rat. ( Abdel-Salam, OM; Arbid, MS; Baiuomy, AR, 2004)
"Ten depressed patients treated with trazodone developed edema and weight gain that was promptly reversed by reduction or discontinuation of trazodone."3.67Peripheral edema associated with trazodone: a report of ten cases. ( Barrnett, J; Brown, R; Frances, A; Kocsis, J; Mann, JJ, 1985)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdel-Salam, OM1
Baiuomy, AR1
Arbid, MS1
Allori, L1
Cioli, V1
Silvestrini, B1
Maguire, J1
Singh, AN1
Barrnett, J1
Frances, A1
Kocsis, J1
Brown, R1
Mann, JJ1

Trials

1 trial available for trazodone and Edema

ArticleYear
Experimental and clinical data indicating a potential use of trazodone in acute stroke.
    Current therapeutic research, clinical and experimental, 1975, Volume: 18, Issue:3

    Topics: Acute Disease; Aged; Animals; Cerebrospinal Fluid; Cerebrovascular Disorders; Clinical Trials as Top

1975

Other Studies

3 other studies available for trazodone and Edema

ArticleYear
Studies on the anti-inflammatory effect of fluoxetine in the rat.
    Pharmacological research, 2004, Volume: 49, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Carrageenan; Celecoxib; Cyc

2004
Allergic type response to trazodone.
    The British journal of psychiatry : the journal of mental science, 1987, Volume: 150

    Topics: Drug Hypersensitivity; Edema; Humans; Male; Middle Aged; Trazodone

1987
Peripheral edema associated with trazodone: a report of ten cases.
    Journal of clinical psychopharmacology, 1985, Volume: 5, Issue:3

    Topics: Adult; Aged; Blood Pressure; Body Weight; Depressive Disorder; Dose-Response Relationship, Drug; Ede

1985