trazodone has been researched along with Dyskinesia, Drug-Induced in 7 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of the present study was to evaluate the efficacy of mianserin and trazodone as antidepressants with serotonin 2 antagonist properties on negative symptoms and tardive dyskinesia in elderly patients with chronic schizophrenia." | 9.08 | Benefits of trazodone and mianserin for patients with late-life chronic schizophrenia and tardive dyskinesia: an add-on, double-blind, placebo-controlled study. ( Fujikawa, T; Furutani, M; Hayashi, T; Horiguchi, J; Nishikawa, T; Takahashi, T; Tawara, Y; Yamawaki, S; Yano, T; Yokota, N, 1997) |
| "The objective of the present study was to evaluate the efficacy of mianserin and trazodone as antidepressants with serotonin 2 antagonist properties on negative symptoms and tardive dyskinesia in elderly patients with chronic schizophrenia." | 5.08 | Benefits of trazodone and mianserin for patients with late-life chronic schizophrenia and tardive dyskinesia: an add-on, double-blind, placebo-controlled study. ( Fujikawa, T; Furutani, M; Hayashi, T; Horiguchi, J; Nishikawa, T; Takahashi, T; Tawara, Y; Yamawaki, S; Yano, T; Yokota, N, 1997) |
| "Trazodone is a clinically available anti-depressant that exhibits affinity for serotonin 1A and 2A receptors, as well as for alpha-adrenoceptors, suggesting that it may be useful to treat L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesia and psychosis that are encountered in advanced Parkinson's disease (PD)." | 1.48 | Trazodone alleviates both dyskinesia and psychosis in the parkinsonian marmoset model of Parkinson's disease. ( Gourdon, JC; Hamadjida, A; Huot, P; Nuara, SG, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamadjida, A | 1 |
| Nuara, SG | 1 |
| Gourdon, JC | 1 |
| Huot, P | 1 |
| Lin, CC | 1 |
| Lin, PY | 1 |
| Lee, Y | 1 |
| Chang, YY | 1 |
| Chen, CH | 1 |
| Sandler, NH | 1 |
| Hayashi, T | 1 |
| Yokota, N | 1 |
| Takahashi, T | 1 |
| Tawara, Y | 1 |
| Nishikawa, T | 1 |
| Yano, T | 1 |
| Furutani, M | 1 |
| Fujikawa, T | 1 |
| Horiguchi, J | 1 |
| Yamawaki, S | 1 |
| Tesler-Mabe, CS | 1 |
| Roccatagliata, G | 1 |
| Albano, C | 1 |
| Besio, G | 1 |
| el-Awar, M | 1 |
| Freedman, M | 1 |
| Seeman, P | 1 |
| Goldenberg, L | 1 |
| Little, J | 1 |
| Solomon, P | 1 |
1 trial available for trazodone and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Benefits of trazodone and mianserin for patients with late-life chronic schizophrenia and tardive dyskinesia: an add-on, double-blind, placebo-controlled study.
Topics: Age Factors; Aged; Antidepressive Agents, Second-Generation; Brief Psychiatric Rating Scale; Double- | 1997 |
6 other studies available for trazodone and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Trazodone alleviates both dyskinesia and psychosis in the parkinsonian marmoset model of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Antipsychotic Agents; Behavior, Animal; Callithrix; Disorders of Exce | 2018 |
Tardive dystonia and tardive sensory syndrome related to trazodone: a case report.
Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Anxiety Disorders; Clonazepam; Dys | 2008 |
Tardive dyskinesia associated with fluoxetine.
Topics: Adult; Clomipramine; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Fluoxetine; Humans; Male; | 1996 |
Acute dystonic reaction with trazodone.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Drug Therapy, Comb | 1998 |
[Late chronic dyskinesia from neuroleptic drugs (CSF and pharmacological data) (author's transl)].
Topics: Adult; Antipsychotic Agents; Brain; Dopamine; Dyskinesia, Drug-Induced; Female; Homovanillic Acid; H | 1978 |
Response of tardive and L-dopa-induced dyskinesias to antidepressants.
Topics: Aged; Antidepressive Agents; Depressive Disorder; Desipramine; Dyskinesia, Drug-Induced; Humans; Lev | 1987 |