trazodone has been researched along with Diffuse Myofascial Pain Syndrome in 3 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with trazodone significantly improved global fibromyalgia severity, sleep quality, and depression, as well as pain interference with daily activities although without showing a direct effect on bodily pain." | 9.15 | Trazodone plus pregabalin combination in the treatment of fibromyalgia: a two-phase, 24-week, open-label uncontrolled study. ( Calandre, EP; Molina-Barea, R; Morillas-Arques, P; Rico-Villademoros, F; Rodriguez-Lopez, CM, 2011) |
| "Despite its frequent use as a hypnotic, trazodone has not been systematically assessed in fibromyalgia patients." | 9.14 | Trazodone for the treatment of fibromyalgia: an open-label, 12-week study. ( Calandre, EP; Molina-Barea, R; Morillas-Arques, P; Rico-Villademoros, F; Rodriguez-Lopez, CM, 2010) |
| "Treatment with trazodone significantly improved global fibromyalgia severity, sleep quality, and depression, as well as pain interference with daily activities although without showing a direct effect on bodily pain." | 5.15 | Trazodone plus pregabalin combination in the treatment of fibromyalgia: a two-phase, 24-week, open-label uncontrolled study. ( Calandre, EP; Molina-Barea, R; Morillas-Arques, P; Rico-Villademoros, F; Rodriguez-Lopez, CM, 2011) |
| "Despite its frequent use as a hypnotic, trazodone has not been systematically assessed in fibromyalgia patients." | 5.14 | Trazodone for the treatment of fibromyalgia: an open-label, 12-week study. ( Calandre, EP; Molina-Barea, R; Morillas-Arques, P; Rico-Villademoros, F; Rodriguez-Lopez, CM, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morillas-Arques, P | 2 |
| Rodriguez-Lopez, CM | 2 |
| Molina-Barea, R | 2 |
| Rico-Villademoros, F | 2 |
| Calandre, EP | 2 |
| Bellometti, S | 1 |
| Galzigna, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Open Label Trial Concerning the Effectiveness of Trazodone in the Treatment of Fibromyalgia (Phase I) and Its Augmentation With Pregabalin in Trazodone Partial Responders (Phase II)[NCT00791739] | Phase 4 | 66 participants (Actual) | Interventional | 2008-04-30 | Completed | ||
| Evaluation of Spa Therapy in the Treatment of Fibromyalgia : a Randomized, Controlled, Open Multicenter Study[NCT02265029] | 220 participants (Actual) | Interventional | 2014-09-30 | Completed | |||
| Evaluation of the Efficiency of a Therapeutic Education Program in Standardized Thermal Cure for Fibromyalgia Patients[NCT02406313] | 152 participants (Actual) | Interventional | 2015-03-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for trazodone and Diffuse Myofascial Pain Syndrome
| Article | Year |
|---|---|
Trazodone for the treatment of fibromyalgia: an open-label, 12-week study.
Topics: Adult; Aged; Female; Fibromyalgia; Humans; Hypnotics and Sedatives; Male; Middle Aged; Selective Ser | 2010 |
Trazodone plus pregabalin combination in the treatment of fibromyalgia: a two-phase, 24-week, open-label uncontrolled study.
Topics: Adult; Analgesics; Analysis of Variance; Anti-Anxiety Agents; Antidepressive Agents, Second-Generati | 2011 |
Function of the hypothalamic adrenal axis in patients with fibromyalgia syndrome undergoing mud-pack treatment.
Topics: Adrenocorticotropic Hormone; Antidepressive Agents, Second-Generation; beta-Endorphin; Combined Moda | 1999 |
Function of the hypothalamic adrenal axis in patients with fibromyalgia syndrome undergoing mud-pack treatment.
Topics: Adrenocorticotropic Hormone; Antidepressive Agents, Second-Generation; beta-Endorphin; Combined Moda | 1999 |
Function of the hypothalamic adrenal axis in patients with fibromyalgia syndrome undergoing mud-pack treatment.
Topics: Adrenocorticotropic Hormone; Antidepressive Agents, Second-Generation; beta-Endorphin; Combined Moda | 1999 |
Function of the hypothalamic adrenal axis in patients with fibromyalgia syndrome undergoing mud-pack treatment.
Topics: Adrenocorticotropic Hormone; Antidepressive Agents, Second-Generation; beta-Endorphin; Combined Moda | 1999 |