trazodone has been researched along with Diabetic Neuropathies in 2 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trazodone (TRZ) is a compound with a multi-modal mechanism of action, being a serotonin-2 antagonist/reuptake inhibitor developed and approved for the treatment of depression in several countries." | 2.94 | Efficacy and Safety of Low Doses of Trazodone in Patients Affected by Painful Diabetic Neuropathy and Treated with Gabapentin: A Randomized Controlled Pilot Study. ( Calisti, F; Cattaneo, A; Comandini, A; Cruccu, G; Del Vecchio, A; Di Loreto, G; Ehler, E; Lipone, P; Nastaj, M; Palka-Kisielowska, I; Pochiero, I; Truini, A, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lipone, P | 1 |
| Ehler, E | 1 |
| Nastaj, M | 1 |
| Palka-Kisielowska, I | 1 |
| Cruccu, G | 1 |
| Truini, A | 1 |
| Di Loreto, G | 1 |
| Del Vecchio, A | 1 |
| Pochiero, I | 1 |
| Comandini, A | 1 |
| Calisti, F | 1 |
| Cattaneo, A | 1 |
| Khurana, RC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Low Doses of Trazodone in Patients Affected by Painful Diabetic Neuropathy: Randomized, Controlled, Pilot Study.[NCT03202979] | Phase 2 | 142 participants (Actual) | Interventional | 2017-05-16 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for trazodone and Diabetic Neuropathies
| Article | Year |
|---|---|
Efficacy and Safety of Low Doses of Trazodone in Patients Affected by Painful Diabetic Neuropathy and Treated with Gabapentin: A Randomized Controlled Pilot Study.
Topics: Aged; Analgesics; Diabetic Neuropathies; Dose-Response Relationship, Drug; Double-Blind Method; Drug | 2020 |
1 other study available for trazodone and Diabetic Neuropathies
| Article | Year |
|---|---|
Treatment of painful diabetic neuropathy with trazodone.
Topics: Diabetic Neuropathies; Humans; Pain; Piperazines; Trazodone | 1983 |