trazodone has been researched along with Dementia Praecox in 11 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of the present study was to evaluate the efficacy of mianserin and trazodone as antidepressants with serotonin 2 antagonist properties on negative symptoms and tardive dyskinesia in elderly patients with chronic schizophrenia." | 9.08 | Benefits of trazodone and mianserin for patients with late-life chronic schizophrenia and tardive dyskinesia: an add-on, double-blind, placebo-controlled study. ( Fujikawa, T; Furutani, M; Hayashi, T; Horiguchi, J; Nishikawa, T; Takahashi, T; Tawara, Y; Yamawaki, S; Yano, T; Yokota, N, 1997) |
| "The study examined whether adjunctive treatment with trazodone would reduce negative symptomatology in patients with chronic, residual schizophrenia." | 9.07 | Adjunctive trazodone in the treatment of negative symptoms of schizophrenia. ( Bocola, V; Decina, P; Hadjichristos, C; Mukherjee, S; Saraceni, F; Scapicchio, P, 1994) |
| " Case description A 49-year-old man with schizophrenia, who was under maintenance treatment with olanzapine 20 mg/day, trihexyphenidyl 4 mg/day, and trazodone 50 mg/day, suffered from heat stroke in a heat wave and required intensive care." | 7.81 | Heat stroke during treatment with olanzapine, trihexyphenidyl, and trazodone in a patient with schizophrenia. ( Chang, CM; Chen, PJ; Lee, CP, 2015) |
| "The objective of the present study was to evaluate the efficacy of mianserin and trazodone as antidepressants with serotonin 2 antagonist properties on negative symptoms and tardive dyskinesia in elderly patients with chronic schizophrenia." | 5.08 | Benefits of trazodone and mianserin for patients with late-life chronic schizophrenia and tardive dyskinesia: an add-on, double-blind, placebo-controlled study. ( Fujikawa, T; Furutani, M; Hayashi, T; Horiguchi, J; Nishikawa, T; Takahashi, T; Tawara, Y; Yamawaki, S; Yano, T; Yokota, N, 1997) |
| "The study examined whether adjunctive treatment with trazodone would reduce negative symptomatology in patients with chronic, residual schizophrenia." | 5.07 | Adjunctive trazodone in the treatment of negative symptoms of schizophrenia. ( Bocola, V; Decina, P; Hadjichristos, C; Mukherjee, S; Saraceni, F; Scapicchio, P, 1994) |
| "To establish the differential indication of trazodone and to find the predictors of its efficacy, we conducted a study in which 45 patients with major depressive disorder and 75 patients with acute schizophrenia were randomly assigned under double-blind conditions to either 400 mg trazodone daily, 150 mg amitriptyline daily, 20 mg haloperidol daily, or placebo daily." | 5.06 | Experimental examination of trazodone. ( Klieser, E; Lehmann, E, 1989) |
| " Case description A 49-year-old man with schizophrenia, who was under maintenance treatment with olanzapine 20 mg/day, trihexyphenidyl 4 mg/day, and trazodone 50 mg/day, suffered from heat stroke in a heat wave and required intensive care." | 3.81 | Heat stroke during treatment with olanzapine, trihexyphenidyl, and trazodone in a patient with schizophrenia. ( Chang, CM; Chen, PJ; Lee, CP, 2015) |
| "Trazodone is a triazolopyridine derivative with antidepressant activity, that is chemically unrelated to other currently available antidepressants." | 3.75 | Trazodone: a review of its pharmacological properties and therapeutic use in depression and anxiety. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, CP | 1 |
| Chen, PJ | 1 |
| Chang, CM | 1 |
| du Toit, RM | 1 |
| Millson, RC | 1 |
| Heaton, JP | 1 |
| Adams, MA | 1 |
| Meco, G | 1 |
| Casacchia, M | 1 |
| Boni, B | 1 |
| Cusimano, G | 1 |
| Carta, A | 1 |
| Iannuccelli, M | 1 |
| Brogden, RN | 1 |
| Heel, RC | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Decina, P | 1 |
| Mukherjee, S | 1 |
| Bocola, V | 1 |
| Saraceni, F | 1 |
| Hadjichristos, C | 1 |
| Scapicchio, P | 1 |
| Hayashi, T | 1 |
| Yokota, N | 1 |
| Takahashi, T | 1 |
| Tawara, Y | 1 |
| Nishikawa, T | 1 |
| Yano, T | 1 |
| Furutani, M | 1 |
| Fujikawa, T | 1 |
| Horiguchi, J | 1 |
| Yamawaki, S | 1 |
| Kaneda, Y | 1 |
| Lehmann, HE | 3 |
| Ban, TA | 3 |
| Deutsch, M | 1 |
| Schwartz, GV | 1 |
| Klieser, E | 1 |
| Lehmann, E | 1 |
1 review available for trazodone and Dementia Praecox
| Article | Year |
|---|---|
Trazodone: a review of its pharmacological properties and therapeutic use in depression and anxiety.
Topics: Aged; Animals; Anxiety Disorders; Brain; Cardiovascular System; Clinical Trials as Topic; Depressive | 1981 |
7 trials available for trazodone and Dementia Praecox
| Article | Year |
|---|---|
Trazodone: a review of its pharmacological properties and therapeutic use in depression and anxiety.
Topics: Aged; Animals; Anxiety Disorders; Brain; Cardiovascular System; Clinical Trials as Topic; Depressive | 1981 |
Adjunctive trazodone in the treatment of negative symptoms of schizophrenia.
Topics: Analysis of Variance; Antipsychotic Agents; Case-Control Studies; Chemotherapy, Adjuvant; Chronic Di | 1994 |
Benefits of trazodone and mianserin for patients with late-life chronic schizophrenia and tardive dyskinesia: an add-on, double-blind, placebo-controlled study.
Topics: Age Factors; Aged; Antidepressive Agents, Second-Generation; Brief Psychiatric Rating Scale; Double- | 1997 |
A placebo-controlled clinical study with trazodone in schizophrenic patients.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Middle | 1977 |
A standard-controlled clinical study with trazodone in schizophrenic patients.
Topics: Adult; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Human | 1977 |
Psychotherapeutic profile of a new psychoactive drug trazodone (AF-1161).
Topics: Adult; Aged; Clinical Trials as Topic; Depression; Female; Humans; Male; Mental Disorders; Middle Ag | 1975 |
Experimental examination of trazodone.
Topics: Adult; Amitriptyline; Anxiety; Depression; Depressive Disorder; Double-Blind Method; Female; Haloper | 1989 |
4 other studies available for trazodone and Dementia Praecox
| Article | Year |
|---|---|
Heat stroke during treatment with olanzapine, trihexyphenidyl, and trazodone in a patient with schizophrenia.
Topics: Amisulpride; Antiparkinson Agents; Antipsychotic Agents; Benzodiazepines; Body Temperature Regulatio | 2015 |
Priapism.
Topics: Adult; Dibenzothiazepines; Drug Therapy, Combination; Humans; Male; Priapism; Quetiapine Fumarate; R | 2004 |
Changed plasma prolactin levels after etoperidone and placebo.
Topics: Adolescent; Adult; Antidepressive Agents; Humans; Kinetics; Male; Middle Aged; Piperazines; Placebos | 1984 |
Successful treatment with trazodone for repetitive behavior in schizophrenia.
Topics: Adult; Humans; Male; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Trazodone | 2001 |