trazodone has been researched along with Coma in 3 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seizures were more common in the amoxapine (24." | 1.27 | Relative toxicity of cyclic antidepressants. ( Gorman, RL; Klein-Schwartz, W; Oderda, GM; Wedin, GP, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Henry, JA | 1 |
| Ali, CJ | 1 |
| Caldwell, R | 1 |
| Flanagan, RJ | 1 |
| Galluzzi, S | 1 |
| Zanetti, O | 1 |
| Binetti, G | 1 |
| Trabucchi, M | 1 |
| Frisoni, GB | 1 |
| Wedin, GP | 1 |
| Oderda, GM | 1 |
| Klein-Schwartz, W | 1 |
| Gorman, RL | 1 |
3 other studies available for trazodone and Coma
| Article | Year |
|---|---|
Acute trazodone poisoning: clinical signs and plasma concentrations.
Topics: Adolescent; Adult; Ataxia; Child; Coma; Dose-Response Relationship, Drug; Female; Humans; Male; Midd | 1984 |
Coma in a patient with Alzheimer's disease taking low dose trazodone and gingko biloba.
Topics: Aged; Alzheimer Disease; Coma; Drug Interactions; Female; Ginkgo biloba; Humans; Plants, Medicinal; | 2000 |
Relative toxicity of cyclic antidepressants.
Topics: Adolescent; Adult; Aged; Amoxapine; Anthracenes; Antidepressive Agents, Tricyclic; Arrhythmias, Card | 1986 |