trazodone has been researched along with Cognitive Decline in 6 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This retrospective study examines whether long-term use of trazodone, an SWS enhancer, is associated with delayed cognitive decline." | 3.91 | Long-Term Trazodone Use and Cognition: A Potential Therapeutic Role for Slow-Wave Sleep Enhancers. ( Karageorgiou, E; Krystal, AD; La, AL; Miller, BL; Neylan, TC; Vossel, KA; Walsh, CM; Yaffe, K, 2019) |
| "Trazodone is a widely used antidepressant that is also useful in the control of agitation and insomnia in Alzheimer's disease." | 2.72 | The effects of trazodone on human cognition: a systematic review. ( Gonçalo, AMG; Vieira-Coelho, MA, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Assimon, MM | 1 |
| Flythe, JE | 1 |
| Gonçalo, AMG | 1 |
| Vieira-Coelho, MA | 1 |
| Boccardi, V | 1 |
| Baroni, M | 1 |
| Paolacci, L | 1 |
| Ercolani, S | 1 |
| Longo, A | 1 |
| Giordano, M | 1 |
| Ruggiero, C | 1 |
| Mecocci, P | 1 |
| Leng, Y | 1 |
| Diem, SJ | 1 |
| Stone, KL | 1 |
| Yaffe, K | 2 |
| Burke, SL | 1 |
| Hu, T | 1 |
| Spadola, CE | 1 |
| Li, T | 1 |
| Naseh, M | 1 |
| Burgess, A | 1 |
| Cadet, T | 1 |
| La, AL | 1 |
| Walsh, CM | 1 |
| Neylan, TC | 1 |
| Vossel, KA | 1 |
| Krystal, AD | 1 |
| Miller, BL | 1 |
| Karageorgiou, E | 1 |
1 review available for trazodone and Cognitive Decline
| Article | Year |
|---|---|
The effects of trazodone on human cognition: a systematic review.
Topics: Antidepressive Agents, Second-Generation; Cognition; Cognitive Dysfunction; Cross-Over Studies; Dose | 2021 |
5 other studies available for trazodone and Cognitive Decline
| Article | Year |
|---|---|
Zolpidem Versus Trazodone Initiation and the Risk of Fall-Related Fractures among Individuals Receiving Maintenance Hemodialysis.
Topics: Accidental Falls; Aged; Cognitive Dysfunction; Dizziness; Drug Prescriptions; Female; Fractures, Bon | 2020 |
Anticholinergic Burden and Functional Status in Older People with Cognitive Impairment: Results from the Regal Project.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Cholinergic Antagonists; Cog | 2017 |
Antidepressant Use and Cognitive Outcomes in Very Old Women.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cognition; Cogniti | 2018 |
Mild cognitive impairment: associations with sleep disturbance, apolipoprotein e4, and sleep medications.
Topics: Aged; Alleles; Anti-Anxiety Agents; Apolipoprotein E4; Cognitive Dysfunction; Female; Genotype; Huma | 2018 |
Long-Term Trazodone Use and Cognition: A Potential Therapeutic Role for Slow-Wave Sleep Enhancers.
Topics: Aged; Alzheimer Disease; Antidepressive Agents, Second-Generation; Case-Control Studies; Cognition; | 2019 |