trazodone has been researched along with Cognition Disorders in 5 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There are no randomized clinical trials regarding efficacy of trazodone in the treatment of sleep disturbances (SD) in patients with Alzheimer disease (AD)." | 9.19 | Trazodone improves sleep parameters in Alzheimer disease patients: a randomized, double-blind, and placebo-controlled study. ( Camargos, EF; Louzada, FM; Louzada, LL; Naves, JO; Nóbrega, OT; Quintas, JL, 2014) |
| "There are no randomized clinical trials regarding efficacy of trazodone in the treatment of sleep disturbances (SD) in patients with Alzheimer disease (AD)." | 5.19 | Trazodone improves sleep parameters in Alzheimer disease patients: a randomized, double-blind, and placebo-controlled study. ( Camargos, EF; Louzada, FM; Louzada, LL; Naves, JO; Nóbrega, OT; Quintas, JL, 2014) |
| "Trazodone 100 mg may cause cognitive driving impairment." | 2.78 | The effect of trazodone on standardized field sobriety tests. ( Barnett, MJ; Bui, QV; Ip, EJ; Kazani, A; Perry, PJ; Serino, MJ; Wright, R, 2013) |
| "Trazodone is an established antidepressant that is prescribed frequently as an off-label hypnotic with wide acceptance among psychiatrists." | 2.47 | Trazodone: properties and utility in multiple disorders. ( Mittur, A, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ip, EJ | 1 |
| Bui, QV | 1 |
| Barnett, MJ | 1 |
| Kazani, A | 1 |
| Wright, R | 1 |
| Serino, MJ | 1 |
| Perry, PJ | 1 |
| Camargos, EF | 1 |
| Louzada, LL | 1 |
| Quintas, JL | 1 |
| Naves, JO | 1 |
| Louzada, FM | 1 |
| Nóbrega, OT | 1 |
| Mittur, A | 1 |
| Stein, DJ | 1 |
| Hemmings, S | 1 |
| Moolman-Smook, H | 1 |
| Audenaert, K | 1 |
| Mizon, JP | 1 |
| Gentit, F | 1 |
| Rosa, A | 1 |
| Danze, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Trazodone for the Treatment of Sleep Disorders in Alzheimer's Disease: a Randomised, Double-blind, Placebo-controlled Study[NCT01142258] | Phase 3 | 40 participants (Actual) | Interventional | 2010-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for trazodone and Cognition Disorders
| Article | Year |
|---|---|
Trazodone: properties and utility in multiple disorders.
Topics: Animals; Anxiety Disorders; Chronic Pain; Cognition Disorders; Depressive Disorder; Humans; Mental D | 2011 |
2 trials available for trazodone and Cognition Disorders
| Article | Year |
|---|---|
The effect of trazodone on standardized field sobriety tests.
Topics: Acetaminophen; Adult; Cognition Disorders; Double-Blind Method; Female; Humans; Male; Psychomotor Pe | 2013 |
Trazodone improves sleep parameters in Alzheimer disease patients: a randomized, double-blind, and placebo-controlled study.
Topics: Actigraphy; Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Comorbidity; Double-Bli | 2014 |
2 other studies available for trazodone and Cognition Disorders
| Article | Year |
|---|---|
5-HT2A: its role in frontally mediated executive function and related psychopathology.
Topics: Attitude; Cognition Disorders; Depressive Disorder, Major; Frontal Lobe; Humans; Male; Positron-Emis | 2007 |
[Iatrogenic mental confusion caused by a new antidepressant in the elderly. Apropos of 2 cases].
Topics: Adjustment Disorders; Aged; Cognition Disorders; Confusion; Female; Humans; Piperazines; Trazodone | 1981 |