trazodone has been researched along with Cardiovascular Diseases in 7 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Severe orthostatic hypotension is more likely to develop in depressed patients with left ventricular impairment and/or in patients taking other drugs like diuretics or vasodilators." | 2.38 | Review of the cardiovascular effects of heterocyclic antidepressants. ( Glassman, AH; Preud'homme, XA, 1993) |
| "Nomifensine was withdrawn from markets worldwide because of reports of serious hypersensitivity reactions, especially hemolytic anemia, and marketing of bupropion in the United States was delayed after seizures occurred in bulimic patients in clinical trials." | 2.37 | Adverse reactions to five new antidepressants. ( Hayes, PE; Kristoff, CA, 1986) |
| "Trazodone has been used widely to treat insomnia in depressed patients." | 1.31 | Electroconvulsive therapy and cardiovascular complications in patients taking trazodone for insomnia. ( Hanson, CA; Krahn, LE; Pileggi, TS; Rummans, TA, 2001) |
| "Trazodone is a psychotropic drug with a clinically proven antidepressant activity." | 1.26 | Comparative cardiovascular toxicity of trazodone and imipramine in the rat. ( Campana, A; Lisciani, R; Scorza Barcellona, P, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Himmelhoch, J | 1 |
| Glassman, AH | 1 |
| Preud'homme, XA | 1 |
| Krahn, LE | 1 |
| Hanson, CA | 1 |
| Pileggi, TS | 1 |
| Rummans, TA | 1 |
| Lisciani, R | 1 |
| Campana, A | 1 |
| Scorza Barcellona, P | 1 |
| Preskorn, SH | 1 |
| Hayes, PE | 1 |
| Kristoff, CA | 1 |
| Prien, RF | 1 |
| Blaine, JD | 1 |
| Levine, J | 1 |
2 reviews available for trazodone and Cardiovascular Diseases
| Article | Year |
|---|---|
Review of the cardiovascular effects of heterocyclic antidepressants.
Topics: Amoxapine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Bupropion; | 1993 |
Adverse reactions to five new antidepressants.
Topics: Acute Kidney Injury; Amoxapine; Animals; Antidepressive Agents; Bupropion; Cardiovascular Diseases; | 1986 |
5 other studies available for trazodone and Cardiovascular Diseases
| Article | Year |
|---|---|
Trazodone.
Topics: Cardiovascular Diseases; Humans; Piperazines; Trazodone | 1981 |
Electroconvulsive therapy and cardiovascular complications in patients taking trazodone for insomnia.
Topics: Adult; Cardiovascular Diseases; Case-Control Studies; Comorbidity; Confidence Intervals; Depressive | 2001 |
Comparative cardiovascular toxicity of trazodone and imipramine in the rat.
Topics: Animals; Blood Pressure; Cardiovascular Diseases; Dose-Response Relationship, Drug; Electrocardiogra | 1978 |
Cardiovascular and central nervous system toxicity of antidepressants.
Topics: Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cardiovascular Diseases; Central Nerv | 1992 |
Antidepressant drug therapy: the role of the new antidepressants.
Topics: Amoxapine; Antidepressive Agents; Bupropion; Cardiovascular Diseases; Depressive Disorder; Drug Eval | 1985 |