trazodone has been researched along with Arthritis, Rheumatoid in 2 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty-seven patients with definite rheumatoid arthritis (RA) were treated in a 32 week, double blind, crossover trial of amitriptyline, desipramine, trazodone, and placebo." | 5.06 | Antidepressant analgesia in rheumatoid arthritis. ( Atwood, C; Beck, NC; Brownlee-Duffeck, M; Elliott, TR; Frank, RG; Haut, AE; Kashani, JH; Kay, DR; Parker, JC; Smith, E, 1988) |
| "Trazodone (Desyrel) is a second-generation, nontricyclic antidepressant that has been in use in North America since the early 1980s." | 1.31 | Trazodone-induced hepatotoxicity: a case report with comments on drug-induced hepatotoxicity. ( Fernandes, NF; Martin, RR; Schenker, S, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fernandes, NF | 1 |
| Martin, RR | 1 |
| Schenker, S | 1 |
| Frank, RG | 1 |
| Kashani, JH | 1 |
| Parker, JC | 1 |
| Beck, NC | 1 |
| Brownlee-Duffeck, M | 1 |
| Elliott, TR | 1 |
| Haut, AE | 1 |
| Atwood, C | 1 |
| Smith, E | 1 |
| Kay, DR | 1 |
1 trial available for trazodone and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Antidepressant analgesia in rheumatoid arthritis.
Topics: Aged; Amitriptyline; Antidepressive Agents; Arthritis, Rheumatoid; Depression; Desipramine; Double-B | 1988 |
1 other study available for trazodone and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Trazodone-induced hepatotoxicity: a case report with comments on drug-induced hepatotoxicity.
Topics: Adult; Anti-Inflammatory Agents; Antidepressive Agents, Second-Generation; Arthritis, Rheumatoid; Ch | 2000 |