trazodone has been researched along with Anxiety Neuroses in 33 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eleven patients with panic disorder or agoraphobia with panic attacks completed an 8-week single-blind trial of trazodone (300 mg/day) without concurrent behavioral instructions." | 9.06 | Trazodone in the treatment of panic disorder and agoraphobia with panic attacks. ( Bowler, K; Dealy, R; Mavissakalian, M; Perel, J, 1987) |
| "To evaluate efficacy of trazodone hydrochloride as an adjunctive treatment for anxiety disorders as well as treatment protocol, dose range, concurrent drug use, adverse events, and therapeutic response in dogs unresponsive to other pharmacologic agents." | 7.74 | Use of trazodone as an adjunctive agent in the treatment of canine anxiety disorders: 56 cases (1995-2007). ( Gruen, ME; Sherman, BL, 2008) |
| "Obstructive sleep apnea (OSA) is a highly prevalent type of sleep-disordered breathing, which is often comorbid with affective disorders such as anxiety." | 5.91 | Successful treatment of auto-trilevel positive airway pressure plus trazodone for obstructive sleep apnea complicated by anxiety disorder: a case report. ( He, X; Lang, Q; Pei, ZM; Yan, HY, 2023) |
| "Eleven patients with panic disorder or agoraphobia with panic attacks completed an 8-week single-blind trial of trazodone (300 mg/day) without concurrent behavioral instructions." | 5.06 | Trazodone in the treatment of panic disorder and agoraphobia with panic attacks. ( Bowler, K; Dealy, R; Mavissakalian, M; Perel, J, 1987) |
| "Trazodone is a triazolopyridine derivative with antidepressant activity, that is chemically unrelated to other currently available antidepressants." | 3.75 | Trazodone: a review of its pharmacological properties and therapeutic use in depression and anxiety. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1981) |
| "To evaluate efficacy of trazodone hydrochloride as an adjunctive treatment for anxiety disorders as well as treatment protocol, dose range, concurrent drug use, adverse events, and therapeutic response in dogs unresponsive to other pharmacologic agents." | 3.74 | Use of trazodone as an adjunctive agent in the treatment of canine anxiety disorders: 56 cases (1995-2007). ( Gruen, ME; Sherman, BL, 2008) |
| "The study consisted of evaluating 80 out-patients for DSM-IV diagnoses and giving 75 mg trazodone for four months to children aged 9-13 who fulfilled DSM-IV criteria for Major Depressive Disorder (n = 22); Major Depressive Disorder and Generalized Anxiety Disorder (n = 24), Major Depressive Disorder and Learning Disorder NOS (n = 24); Major Depressive Disorder and Oppositional Defiant Disorder (n = 10)." | 3.69 | Depressive disorder in pre-adolescence: comorbidity or different clinical subtypes? (A pharmacological contribution). ( Levi, G; Sogos, C, 1997) |
| "Trazodone was well tolerated, even in combination with NSAIDs, antimicrobials, and other medications; no dogs were withdrawn from the study because of adverse reactions." | 2.79 | Use of trazodone to facilitate postsurgical confinement in dogs. ( Griffith, E; Gruen, ME; Hamilton, A; Roe, SC; Sherman, BL, 2014) |
| "In contrast, persistent insomnia measured both by the HRSD-17 insomnia subscale and the PSQI predicted recurrence." | 2.73 | Which symptoms predict recurrence of depression in women treated with maintenance interpersonal psychotherapy? ( Andreescu, C; Buysse, DJ; Cyranowski, JM; Dombrovski, AY; Frank, E; Houck, PR; Mallinger, AG; Mulsant, BH; Thase, ME, 2008) |
| "Trazodone is an established antidepressant that is prescribed frequently as an off-label hypnotic with wide acceptance among psychiatrists." | 2.47 | Trazodone: properties and utility in multiple disorders. ( Mittur, A, 2011) |
| "Trazodone was associated with lower side effects and with augmentation treatments." | 1.91 | Characterisation of medication side effects in patients with mostly resistant depression in a real-world setting. ( De Ronchi, D; Fabbri, C; Ferentinos, P; Kasper, S; Mendlewicz, J; Montgomery, S; Panariello, F; Rujescu, D; Serretti, A; Souery, D; Zohar, J, 2023) |
| "Obstructive sleep apnea (OSA) is a highly prevalent type of sleep-disordered breathing, which is often comorbid with affective disorders such as anxiety." | 1.91 | Successful treatment of auto-trilevel positive airway pressure plus trazodone for obstructive sleep apnea complicated by anxiety disorder: a case report. ( He, X; Lang, Q; Pei, ZM; Yan, HY, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (33.33) | 18.7374 |
| 1990's | 9 (27.27) | 18.2507 |
| 2000's | 4 (12.12) | 29.6817 |
| 2010's | 7 (21.21) | 24.3611 |
| 2020's | 2 (6.06) | 2.80 |
| Authors | Studies |
|---|---|
| Panariello, F | 1 |
| Kasper, S | 1 |
| Zohar, J | 1 |
| Souery, D | 1 |
| Montgomery, S | 1 |
| Ferentinos, P | 1 |
| Rujescu, D | 1 |
| Mendlewicz, J | 1 |
| De Ronchi, D | 1 |
| Serretti, A | 1 |
| Fabbri, C | 1 |
| He, X | 1 |
| Lang, Q | 1 |
| Pei, ZM | 1 |
| Yan, HY | 1 |
| Osváth, P | 1 |
| Gruen, ME | 3 |
| Roe, SC | 2 |
| Griffith, E | 2 |
| Hamilton, A | 2 |
| Sherman, BL | 3 |
| Petty, MC | 1 |
| Gilbert-Gregory, SE | 1 |
| Stull, JW | 1 |
| Rice, MR | 1 |
| Herron, ME | 1 |
| Lin, CC | 1 |
| Lin, PY | 1 |
| Lee, Y | 1 |
| Chang, YY | 1 |
| Chen, CH | 1 |
| Dombrovski, AY | 1 |
| Cyranowski, JM | 1 |
| Mulsant, BH | 1 |
| Houck, PR | 1 |
| Buysse, DJ | 1 |
| Andreescu, C | 1 |
| Thase, ME | 1 |
| Mallinger, AG | 1 |
| Frank, E | 1 |
| Mittur, A | 1 |
| Lund, BC | 1 |
| Bernardy, NC | 1 |
| Vaughan-Sarrazin, M | 1 |
| Alexander, B | 1 |
| Friedman, MJ | 1 |
| Ayd, FJ | 1 |
| Settle, EC | 1 |
| Himmelhoch, JM | 1 |
| Schechtman, K | 1 |
| Auchenbach, R | 1 |
| Beaumont, G | 1 |
| Gringras, M | 1 |
| Ankier, SI | 1 |
| Carney, PA | 1 |
| Healy, D | 1 |
| Leonard, BE | 1 |
| Brogden, RN | 1 |
| Heel, RC | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Fernandez, F | 1 |
| Levy, JK | 1 |
| Forster, P | 1 |
| King, J | 1 |
| Jackson, CW | 1 |
| Morton, WA | 1 |
| Lydiard, RB | 1 |
| Rickels, K | 1 |
| Downing, R | 1 |
| Schweizer, E | 1 |
| Hassman, H | 1 |
| Rothschild, AJ | 1 |
| Mintzer, JE | 1 |
| Brawman-Mintzer, O | 1 |
| Levi, G | 1 |
| Sogos, C | 1 |
| Haida, M | 1 |
| Itoh, K | 1 |
| Rao, R | 1 |
| Lantz, MS | 1 |
| Imaz, F | 1 |
| Pecknold, JC | 1 |
| Ban, TA | 1 |
| Liebowitz, NR | 1 |
| el-Mallakh, RS | 1 |
| Cole, JO | 1 |
| Mavissakalian, M | 1 |
| Perel, J | 1 |
| Bowler, K | 1 |
| Dealy, R | 1 |
| Charney, DS | 1 |
| Woods, SW | 1 |
| Goodman, WK | 1 |
| Rifkin, B | 1 |
| Kinch, M | 1 |
| Aiken, B | 1 |
| Quadrino, LM | 1 |
| Heninger, GR | 1 |
| Menza, MA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Maintenance Psychotherapies in Recurrent Depression: Study II[NCT00227981] | 93 participants | Interventional | 1995-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for trazodone and Anxiety Neuroses
| Article | Year |
|---|---|
[Current treatment of depression and agitation in the elderly -- clinical use of trazodone].
Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Second-G | 2013 |
Trazodone: properties and utility in multiple disorders.
Topics: Animals; Anxiety Disorders; Chronic Pain; Cognition Disorders; Depressive Disorder; Humans; Mental D | 2011 |
Trazodone: a novel, broad-spectrum antidepressant.
Topics: Animals; Anxiety Disorders; Depressive Disorder; Hemodynamics; Humans; Neurotransmitter Agents; Para | 1982 |
Trazodone: a review of its pharmacological properties and therapeutic use in depression and anxiety.
Topics: Aged; Animals; Anxiety Disorders; Brain; Cardiovascular System; Clinical Trials as Topic; Depressive | 1981 |
Psychopharmacology in HIV spectrum disorders.
Topics: Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; Anti-Anxiety Agents; Antipsychotic Agents | 1994 |
Definitive treatment of patients with serious mental disorders in an emergency service, Part I.
Topics: Antidepressive Agents; Anxiety Disorders; Depressive Disorder; Emergency Services, Psychiatric; Hosp | 1994 |
The diagnosis and treatment of late-life depression.
Topics: Age Factors; Aged; Antidepressive Agents; Anxiety Disorders; Bupropion; Cyclohexanols; Depressive Di | 1996 |
Agitation as a possible expression of generalized anxiety disorder in demented elderly patients: toward a treatment approach.
Topics: Aged; Aggression; Antipsychotic Agents; Anxiety Disorders; Behavior Therapy; Buspirone; Carbamazepin | 1996 |
The drug treatment of anxiety and depression.
Topics: Antidepressive Agents, Tricyclic; Anxiety Disorders; Benzodiazepines; Depressive Disorder; Humans; M | 1988 |
10 trials available for trazodone and Anxiety Neuroses
| Article | Year |
|---|---|
Use of trazodone to facilitate postsurgical confinement in dogs.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Dog Diseases; Dogs; Orthopedic Procedures; | 2014 |
Effects of trazodone on behavioral signs of stress in hospitalized dogs.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Behavior, Animal; Dog Diseases; Dogs; Female; Hospi | 2016 |
Which symptoms predict recurrence of depression in women treated with maintenance interpersonal psychotherapy?
Topics: Adult; Affect; Anxiety Disorders; Combined Modality Therapy; Comorbidity; Depressive Disorder, Major | 2008 |
Trazodone and mianserin in general practice.
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder; Dibenzazepines; Double-Blin | 1984 |
A double-blind study to compare trazodone with amitriptyline in depressed patients.
Topics: Adult; Amitriptyline; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder; Dose-Respons | 1984 |
Trazodone: a review of its pharmacological properties and therapeutic use in depression and anxiety.
Topics: Aged; Animals; Anxiety Disorders; Brain; Cardiovascular System; Clinical Trials as Topic; Depressive | 1981 |
Antidepressants for the treatment of generalized anxiety disorder. A placebo-controlled comparison of imipramine, trazodone, and diazepam.
Topics: Adult; Aged; Anxiety Disorders; Diazepam; Double-Blind Method; Drug Administration Schedule; Female; | 1993 |
Trazodone in the treatment of neurosis--an uncontrolled clinical study.
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Piperazines; | 1976 |
Trazodone in the treatment of panic disorder and agoraphobia with panic attacks.
Topics: Adult; Agoraphobia; Ambulatory Care; Anxiety Disorders; Clinical Trials as Topic; Fear; Female; Huma | 1987 |
Drug treatment of panic disorder: the comparative efficacy of imipramine, alprazolam, and trazodone.
Topics: Agoraphobia; Alprazolam; Anxiety Disorders; Clinical Trials as Topic; Fear; Humans; Imipramine; Pani | 1986 |
15 other studies available for trazodone and Anxiety Neuroses
| Article | Year |
|---|---|
Characterisation of medication side effects in patients with mostly resistant depression in a real-world setting.
Topics: Anxiety Disorders; Depression; Depressive Disorder, Treatment-Resistant; Drug-Related Side Effects a | 2023 |
Successful treatment of auto-trilevel positive airway pressure plus trazodone for obstructive sleep apnea complicated by anxiety disorder: a case report.
Topics: Anxiety; Anxiety Disorders; Female; Humans; Middle Aged; Sleep Apnea Syndromes; Sleep Apnea, Obstruc | 2023 |
Use of trazodone to facilitate postsurgical confinement in dogs.
Topics: Animals; Anxiety; Anxiety Disorders; Dog Diseases; Orthopedic Procedures; Trazodone | 2014 |
The authors respond.
Topics: Animals; Anxiety; Anxiety Disorders; Dog Diseases; Orthopedic Procedures; Trazodone | 2014 |
Tardive dystonia and tardive sensory syndrome related to trazodone: a case report.
Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Anxiety Disorders; Clonazepam; Dys | 2008 |
Use of trazodone as an adjunctive agent in the treatment of canine anxiety disorders: 56 cases (1995-2007).
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Behavior, Animal; Chemotherapy, Adjuvant; Dog Disea | 2008 |
Patient and facility characteristics associated with benzodiazepine prescribing for veterans with PTSD.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Comorbidity; Cross-Sectional Studies | 2013 |
The role of trazodone in the treatment of depressed cardiac patients.
Topics: Aged; Anxiety Disorders; Arrhythmias, Cardiac; Bipolar Disorder; Cardiac Complexes, Premature; Depre | 1984 |
Pharmacologic management of obsessive-compulsive disorder.
Topics: 1-Naphthylamine; Antidepressive Agents; Anxiety Disorders; Clomipramine; Depression; Dopamine; Fluox | 1994 |
Depressive disorder in pre-adolescence: comorbidity or different clinical subtypes? (A pharmacological contribution).
Topics: Adolescent; Antidepressive Agents; Anxiety Disorders; Child; Depressive Disorder; Female; Humans; Le | 1997 |
[Clinical effect of alprazolam and trazodone on bronchial asthmatics with anxiety disorder].
Topics: Adult; Aged; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Asthma; Female; Humans; Male; Middl | 1997 |
Serotonergic syndrome with trazodone.
Topics: Aged; Antidepressive Agents; Anxiety Disorders; Brain; Humans; Male; Selective Serotonin Reuptake In | 1998 |
Serotonin syndrome. A common but often unrecognized psychiatric condition.
Topics: Aged; Anxiety Disorders; Buspirone; Citalopram; Depression; Female; Humans; Selective Serotonin Reup | 2001 |
Trazodone for the treatment of anxiety symptoms in substance abusers.
Topics: Adult; Alcoholism; Anxiety Disorders; Combat Disorders; Humans; Male; Middle Aged; Sleep Initiation | 1989 |
Withdrawal syndrome in a depressed patient treated with trazodone.
Topics: Adult; Anxiety Disorders; Depersonalization; Depressive Disorder; Dreams; Humans; Male; Sleep Initia | 1986 |