trazodone has been researched along with Aggression in 23 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The evaluation of therapeutic efficiency and safety of using trazodone in treatment of adjustment disorders with the particular focus on dominant symptoms in this illness that is anxiety, lowering of the mood, low self-esteem, sleep disorders and also aggression level." | 7.73 | [The efficacy and safety of trazodone in the treatment of adjustment disorders--naturalistic research]. ( Florkowski, A; Gałecki, P; Zboralski, K, 2005) |
| "A case of 19 year old male with hydrocephalus is reported whose aggressive self-injurious behaviors were resistant to conventional pharmacotherapy but successfully treated by trazodone." | 6.39 | Trazodone for aggression in an adolescent with hydrocephalus. ( Mashiko, H; Matsumoto, H; Niwa, S; Yokoyama, H, 1996) |
| "The evaluation of therapeutic efficiency and safety of using trazodone in treatment of adjustment disorders with the particular focus on dominant symptoms in this illness that is anxiety, lowering of the mood, low self-esteem, sleep disorders and also aggression level." | 3.73 | [The efficacy and safety of trazodone in the treatment of adjustment disorders--naturalistic research]. ( Florkowski, A; Gałecki, P; Zboralski, K, 2005) |
| "Seven patients with organic mental disorders and physically aggressive behavior were treated with trazodone." | 2.66 | Effects of trazodone on aggressive behavior in seven patients with organic mental disorders. ( Pinner, E; Rich, CL, 1988) |
| "A case of 19 year old male with hydrocephalus is reported whose aggressive self-injurious behaviors were resistant to conventional pharmacotherapy but successfully treated by trazodone." | 2.39 | Trazodone for aggression in an adolescent with hydrocephalus. ( Mashiko, H; Matsumoto, H; Niwa, S; Yokoyama, H, 1996) |
| " Chronic administration of the synthetic gonadotropin (luteinising hormone) releasing hormone analogue, goserelin, reduces testosterone activity." | 1.33 | Gonadotrophin-releasing hormone agonist treatment of aggression in Alzheimer's disease: a case report. ( Raskind, MA; Rosin, RA, 2005) |
| " The effects observed indicate that the chronic administration of AD leads to the development of the increased responsiveness (or activation) of the noradrenergic system." | 1.26 | Atypical antidepressant drugs - psychopharmacological profile and mechanism of action. ( Maj, J, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (39.13) | 18.7374 |
| 1990's | 8 (34.78) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calder, CD | 1 |
| Rosin, RA | 1 |
| Raskind, MA | 1 |
| Gałecki, P | 1 |
| Zboralski, K | 1 |
| Florkowski, A | 1 |
| Kitamura, Y | 1 |
| Kudo, Y | 1 |
| Imamura, T | 1 |
| Warrington, SJ | 1 |
| Ankier, SI | 1 |
| Turner, P | 1 |
| Maj, J | 1 |
| Lebert, F | 1 |
| Pasquier, F | 1 |
| Petit, H | 1 |
| Mintzer, JE | 1 |
| Brawman-Mintzer, O | 1 |
| Mashiko, H | 1 |
| Yokoyama, H | 1 |
| Matsumoto, H | 1 |
| Niwa, S | 1 |
| Nguyen, M | 1 |
| Myers, WC | 1 |
| Rudissaar, R | 1 |
| Pruus, K | 1 |
| Vaarmann, A | 1 |
| Pannel, P | 1 |
| Skrebuhhova-Malmros, T | 1 |
| Allikmets, L | 1 |
| Matto, V | 1 |
| Anfinson, T | 1 |
| Zubieta, JK | 1 |
| Alessi, NE | 1 |
| Bernstein, L | 1 |
| Gedye, A | 2 |
| Patterson, BD | 1 |
| Srisopark, MM | 1 |
| Eimer, M | 1 |
| Simpson, DM | 1 |
| Foster, D | 1 |
| O'Neil, M | 1 |
| Page, N | 1 |
| Adkins, WN | 1 |
| Eichelman, B | 1 |
| Wilcock, GK | 1 |
| Stevens, J | 1 |
| Perkins, A | 1 |
| Pinner, E | 1 |
| Rich, CL | 1 |
| Valdman, AV | 1 |
| Poshivalov, VP | 1 |
3 reviews available for trazodone and Aggression
| Article | Year |
|---|---|
Agitation as a possible expression of generalized anxiety disorder in demented elderly patients: toward a treatment approach.
Topics: Aged; Aggression; Antipsychotic Agents; Anxiety Disorders; Behavior Therapy; Buspirone; Carbamazepin | 1996 |
Trazodone for aggression in an adolescent with hydrocephalus.
Topics: Adolescent; Adult; Aged; Aggression; Antipsychotic Agents; Electroconvulsive Therapy; Family Therapy | 1996 |
Management of the behavioral symptoms associated with dementia.
Topics: Aged; Aggression; Antipsychotic Agents; Dementia; Humans; Pindolol; Propranolol; Psychomotor Agitati | 1989 |
4 trials available for trazodone and Aggression
| Article | Year |
|---|---|
An evaluation of possible interactions between ethanol and trazodone or amitriptyline.
Topics: Adult; Aggression; Amitriptyline; Drug Interactions; Ethanol; Female; Flicker Fusion; Humans; Kineti | 1984 |
Behavioral effects of trazodone in Alzheimer's disease.
Topics: Affective Symptoms; Aged; Aggression; Alzheimer Disease; Anxiety; Female; Follow-Up Studies; Humans; | 1994 |
Acute and chronic administration of trazodone in the treatment of disruptive behavior disorders in children.
Topics: Aggression; Child; Child Behavior Disorders; Female; Follow-Up Studies; Hospitalization; Humans; Imp | 1992 |
Effects of trazodone on aggressive behavior in seven patients with organic mental disorders.
Topics: Aged; Aggression; Behavior Therapy; Clinical Trials as Topic; Humans; Male; Middle Aged; Neurocognit | 1988 |
16 other studies available for trazodone and Aggression
| Article | Year |
|---|---|
Animal Behavior Case of the Month.
Topics: Aggression; Animals; Anti-Anxiety Agents; Behavior Therapy; Behavior, Animal; Dogs; Environment; Fea | 2019 |
Gonadotrophin-releasing hormone agonist treatment of aggression in Alzheimer's disease: a case report.
Topics: Aged; Aggression; Alzheimer Disease; Amines; Antipsychotic Agents; Benzodiazepines; Cyclohexanecarbo | 2005 |
[The efficacy and safety of trazodone in the treatment of adjustment disorders--naturalistic research].
Topics: Adjustment Disorders; Adult; Affect; Aggression; Anxiety; Depression; Female; Humans; Male; Psychiat | 2005 |
[Trazodone for the treatment of behavioral and psychological symptoms of dementia (BPSD) in Alzheimer's disease: a retrospective study focused on the aggression and negativism in caregiving situations].
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aggression; Alzheimer Disease; Anti-Anxiety Age | 2006 |
Atypical antidepressant drugs - psychopharmacological profile and mechanism of action.
Topics: Aggression; Animals; Antidepressive Agents; Behavior, Animal; Drug Interactions; Humans; Iprindole; | 1982 |
Trazodone for symptoms of frontal lobe atrophy.
Topics: Adolescent; Aggression; Atrophy; Attention Deficit Disorder with Hyperactivity; Child; Dementia; Fet | 2000 |
Acute trazodone and quipazine treatment attenuates apomorphine-induced aggressive behaviour in male rats without major impact on emotional behaviour or monoamine content post mortem.
Topics: Aggression; Animals; Antidepressive Agents, Second-Generation; Apomorphine; Behavior, Animal; Biogen | 2001 |
Pharmacologic management of aggression and violence.
Topics: Adrenergic beta-Antagonists; Aggression; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Contr | 1992 |
Trazodone treatment of targeted aggression in a mentally retarded man.
Topics: Acting Out; Adult; Aggression; Humans; Intellectual Disability; Male; Prisons; Trazodone | 1992 |
Serotonergic treatment for aggression in a Down's syndrome adult showing signs of Alzheimer's disease.
Topics: Aggression; Alzheimer Disease; Arousal; Brain; Combined Modality Therapy; Down Syndrome; Feeding Beh | 1991 |
Trazodone reduced aggressive and self-injurious movements in a mentally handicapped male patient with autism.
Topics: Adolescent; Aggression; Autistic Disorder; Humans; Intellectual Disability; Male; Self-Injurious Beh | 1991 |
Severe anorexia and possible psychosis or hypomania after trazodone-tryptophan treatment of aggression.
Topics: Adult; Aggression; Anorexia Nervosa; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Ps | 1989 |
Improvement in organically disturbed behavior with trazodone treatment.
Topics: Aged; Aggression; Alcohol Amnestic Disorder; Alzheimer Disease; Animals; Antipsychotic Agents; Human | 1986 |
Tryptophan-trazodone treatment of aggressive behaviour.
Topics: Adult; Aggression; De Lange Syndrome; Drug Therapy, Combination; Humans; Imipramine; Male; Trazodone | 1986 |
Trazodone/tryptophan for aggressive behaviour.
Topics: Adult; Aged; Aged, 80 and over; Aggression; Drug Therapy, Combination; Female; Humans; Male; Trazodo | 1987 |
Pharmaco-ethological analysis of antidepressant drug effects.
Topics: Aggression; Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Fluoxetine; Imipramine; I | 1986 |