trazodone has been researched along with Age-Related Memory Disorders in 3 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In a 9 week dosing regimen, trazodone decreased microglial NLRP3 inflammasome expression and phosphorylated p38 mitogen-activated protein kinase levels, which correlated with the NLRP3 inflammasome, the UPR effector ATF4, and total tau levels." | 1.72 | Improved Sleep, Memory, and Cellular Pathological Features of Tauopathy, Including the NLRP3 Inflammasome, after Chronic Administration of Trazodone in rTg4510 Mice. ( Cella, C; de Oliveira, P; Dijk, DJ; Gilmour, G; Locker, N; Mendis, A; Ravindran, KKG; Wafford, K; Winsky-Sommerer, R, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| de Oliveira, P | 1 |
| Cella, C | 1 |
| Locker, N | 1 |
| Ravindran, KKG | 1 |
| Mendis, A | 1 |
| Wafford, K | 1 |
| Gilmour, G | 1 |
| Dijk, DJ | 1 |
| Winsky-Sommerer, R | 1 |
| Halliday, M | 1 |
| Radford, H | 1 |
| Zents, KAM | 1 |
| Molloy, C | 1 |
| Moreno, JA | 1 |
| Verity, NC | 1 |
| Smith, E | 1 |
| Ortori, CA | 1 |
| Barrett, DA | 1 |
| Bushell, M | 1 |
| Mallucci, GR | 1 |
| Bloomfield, K | 1 |
| Pulliam, E | 1 |
| Schultz, E | 1 |
| Ward, WL | 1 |
3 other studies available for trazodone and Age-Related Memory Disorders
| Article | Year |
|---|---|
Improved Sleep, Memory, and Cellular Pathological Features of Tauopathy, Including the NLRP3 Inflammasome, after Chronic Administration of Trazodone in rTg4510 Mice.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Disease Progression; Humans; Inflammasomes; Male | 2022 |
Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice.
Topics: Animals; Behavior, Animal; Chalcones; Disease Models, Animal; eIF-2 Kinase; Frontotemporal Dementia; | 2017 |
Russian Adoption: A Case Study With Mixed Clinical Presentation.
Topics: Adoption; Amphetamines; Antipsychotic Agents; Asperger Syndrome; Central Nervous System Stimulants; | 2015 |