Page last updated: 2024-11-05

trazodone and Adverse Drug Event

trazodone has been researched along with Adverse Drug Event in 8 studies

Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.

Research Excerpts

ExcerptRelevanceReference
"The aim of the study was to evaluate the efficacy, tolerability, and safety of once-a day trazodone tablets (Trittico Prolong® 300 mg) in patients with moderate to severe depression in routine clinical practice."7.88Once-a-Day Trazodone in the Treatment of Depression in Routine Clinical Practice. ( Češková, E; Kellnerová, R; Šedová, M; Starobová, O, 2018)
"The aim of the study was to evaluate the efficacy, tolerability, and safety of once-a day trazodone tablets (Trittico Prolong® 300 mg) in patients with moderate to severe depression in routine clinical practice."3.88Once-a-Day Trazodone in the Treatment of Depression in Routine Clinical Practice. ( Češková, E; Kellnerová, R; Šedová, M; Starobová, O, 2018)
"Trazodone was associated with lower side effects and with augmentation treatments."1.91Characterisation of medication side effects in patients with mostly resistant depression in a real-world setting. ( De Ronchi, D; Fabbri, C; Ferentinos, P; Kasper, S; Mendlewicz, J; Montgomery, S; Panariello, F; Rujescu, D; Serretti, A; Souery, D; Zohar, J, 2023)
" We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts."1.37FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011)
"5 million adverse drug reaction (ADR) reports for 8620 drugs/biologics that are listed for 1191 Coding Symbols for Thesaurus of Adverse Reaction (COSTAR) terms of adverse effects."1.32Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. ( Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL, 2004)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Matthews, EJ1
Kruhlak, NL1
Weaver, JL1
Benz, RD1
Contrera, JF1
Chen, M1
Vijay, V1
Shi, Q2
Liu, Z2
Fang, H2
Tong, W2
Ding, D1
Kelly, R1
Morgan, RE1
van Staden, CJ1
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Afshari, CA1
Hamadeh, HK1
Panariello, F1
Kasper, S1
Zohar, J1
Souery, D1
Montgomery, S1
Ferentinos, P1
Rujescu, D1
Mendlewicz, J1
De Ronchi, D1
Serretti, A1
Fabbri, C1
Češková, E1
Šedová, M1
Kellnerová, R1
Starobová, O1
Birur, B1
Fargason, RE1
Moore, N1
Kast, RE1

Other Studies

8 other studies available for trazodone and Adverse Drug Event

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Dru

2004
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
Characterisation of medication side effects in patients with mostly resistant depression in a real-world setting.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2023, Volume: 24, Issue:5

    Topics: Anxiety Disorders; Depression; Depressive Disorder, Treatment-Resistant; Drug-Related Side Effects a

2023
Once-a-Day Trazodone in the Treatment of Depression in Routine Clinical Practice.
    Pharmacology, 2018, Volume: 102, Issue:3-4

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Depression; Drug Administration Schedule; Dru

2018
Delayed-onset of psychopharmacologically induced priapism: A cautionary case report.
    Asian journal of psychiatry, 2015, Volume: 17

    Topics: Adult; Antipsychotic Agents; Drug Interactions; Drug Substitution; Drug-Related Side Effects and Adv

2015
Trazodone generates m-CPP: in 2008 risks from m-CPP might outweigh benefits of trazodone.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2009, Volume: 10, Issue:4 Pt 2

    Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Biotransformation; Brain; Dose-Response

2009