trapidil has been researched along with Vasospasm, Intracranial in 2 studies
Trapidil: A coronary vasodilator agent.
Vasospasm, Intracranial: Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).
| Excerpt | Relevance | Reference |
|---|---|---|
| "After subarachnoid hemorrhage (SAH), platelet-derived growth factor-BB (PDGF-BB) is secreted in and around the cerebral arteries." | 1.36 | Platelet-derived growth factor-induced severe and chronic vasoconstriction of cerebral arteries: proposed growth factor explanation of cerebral vasospasm. ( Iihara, K; Kikuchi, H; Miyamoto, S; Nagata, I; Nakajo, Y; Xue, JH; Yanamoto, H; Zhang, ZW, 2010) |
| "Trapidil was shown to have a clear spasmolytic effect on the rabbit's basilar artery." | 1.31 | Resolution of cerebral vasospasm with trapidil; an animal model. ( Bagdatoglu, C; Berk, C; Egemen, N; Guleryuz, A; Kanik, A; Koksel, T; Ozdemir, C; Unlu, A, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, ZW | 1 |
| Yanamoto, H | 1 |
| Nagata, I | 1 |
| Miyamoto, S | 1 |
| Nakajo, Y | 1 |
| Xue, JH | 1 |
| Iihara, K | 1 |
| Kikuchi, H | 1 |
| Bagdatoglu, C | 1 |
| Guleryuz, A | 1 |
| Unlu, A | 1 |
| Kanik, A | 1 |
| Berk, C | 1 |
| Ozdemir, C | 1 |
| Koksel, T | 1 |
| Egemen, N | 1 |
2 other studies available for trapidil and Vasospasm, Intracranial
| Article | Year |
|---|---|
Platelet-derived growth factor-induced severe and chronic vasoconstriction of cerebral arteries: proposed growth factor explanation of cerebral vasospasm.
Topics: Animals; Cerebral Angiography; Cerebral Arteries; Disease Models, Animal; Dose-Response Relationship | 2010 |
Resolution of cerebral vasospasm with trapidil; an animal model.
Topics: Animals; Basilar Artery; Disease Models, Animal; Female; Male; Platelet Aggregation Inhibitors; Rabb | 2002 |