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trapidil and Myocardial Ischemia

trapidil has been researched along with Myocardial Ischemia in 5 studies

Trapidil: A coronary vasodilator agent.

Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Research Excerpts

ExcerptRelevanceReference
"Adenosine and related compounds have been shown to produce atrioventricular (AV) conduction block during acute myocardial ischemia."7.78Effects of the antianginal drug trapidil on atrioventricular conduction disturbances during acute myocardial ischemia. ( Hirayama, A; Kasamaki, Y; Kofune, M; Mano, H; Nagashima, K; Ohkubo, K; Okumura, Y; Sonoda, K; Watanabe, I, 2012)
"Adenosine and related compounds have been shown to produce atrioventricular (AV) conduction block during acute myocardial ischemia."3.78Effects of the antianginal drug trapidil on atrioventricular conduction disturbances during acute myocardial ischemia. ( Hirayama, A; Kasamaki, Y; Kofune, M; Mano, H; Nagashima, K; Ohkubo, K; Okumura, Y; Sonoda, K; Watanabe, I, 2012)
"Aspirin was given to all patients, and ticlopidine 250 mg b."2.71Starc II, a multicenter randomized placebo-controlled double-blind clinical trial of trapidil for 1-year clinical events and angiographic restenosis reduction after coronary angioplasty and stenting. ( Balducelli, M; Barlera, S; Bernardi, G; Latini, R; Maggioni, AP; Maresta, A; Moccetti, T; Monici Preti, A; Ribeiro da Silva, EE; Sosa, C; Varani, E, 2005)
"Trapidil has shown a more complete antithrombocytic activity than other antiaggregating drugs; as a matter of fact it inhibits the formation of TXA2 through a mechanism of receptorial antagonism and at the same time it favours an increase of prostacyclina from the arterial walls."2.38[Trapidil after one year]. ( Agus, GB, 1993)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Watanabe, I1
Okumura, Y1
Nagashima, K1
Kofune, M1
Ohkubo, K1
Mano, H1
Sonoda, K1
Kasamaki, Y1
Hirayama, A1
Maresta, A1
Balducelli, M1
Latini, R1
Bernardi, G1
Moccetti, T1
Sosa, C1
Barlera, S1
Varani, E1
Ribeiro da Silva, EE1
Monici Preti, A1
Maggioni, AP1
Agus, GB1
Kotake, H1
Sawada, Y1
Hoshio, A1
Shirota, K1
Nawada, T1
Yoshida, A1
Hisatome, I1
Miyakoda, H1
Mashiba, H1
Satoh, T1
Otsuka, K1
Sakurai, I1

Reviews

1 review available for trapidil and Myocardial Ischemia

ArticleYear
[Trapidil after one year].
    Minerva cardioangiologica, 1993, Volume: 41, Issue:5

    Topics: Anticoagulants; Arm; Arteriosclerosis; Brain Ischemia; Clinical Trials as Topic; Drug Evaluation; Hu

1993

Trials

1 trial available for trapidil and Myocardial Ischemia

ArticleYear
Starc II, a multicenter randomized placebo-controlled double-blind clinical trial of trapidil for 1-year clinical events and angiographic restenosis reduction after coronary angioplasty and stenting.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2005, Volume: 64, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Vessel Prosthesis Implantation; Coronary Angiography;

2005

Other Studies

3 other studies available for trapidil and Myocardial Ischemia

ArticleYear
Effects of the antianginal drug trapidil on atrioventricular conduction disturbances during acute myocardial ischemia.
    International heart journal, 2012, Volume: 53, Issue:3

    Topics: Adenosine; Angina Pectoris; Animals; Atrioventricular Block; Atrioventricular Node; Bundle of His; D

2012
Effect of trapidil on serum lipid and apolipoprotein levels in patients with ischemic heart disease.
    General pharmacology, 1993, Volume: 24, Issue:2

    Topics: Aged; Apolipoproteins; Cholesterol, HDL; Female; Humans; Lipids; Male; Middle Aged; Myocardial Ische

1993
[Method of quantitative measurement of human platelet aggregation in clinical practice].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1998, Volume: 35, Issue:10

    Topics: Adenosine Diphosphate; Adult; Aged; Aspirin; Dipyridamole; Epinephrine; Female; Humans; Male; Method

1998