Page last updated: 2024-11-05

trapidil and Liver Dysfunction

trapidil has been researched along with Liver Dysfunction in 3 studies

Trapidil: A coronary vasodilator agent.

Research Excerpts

ExcerptRelevanceReference
"Trapidil was given orally (200 mg, Rocornal dragees 100 mg) as well as intravenously (100 mg) in random order."2.67Pharmacokinetics of trapidil (Rocornal) in patients with chronic liver disease. ( Berndt, A; Pönicke, K; Weiss, M, 1992)
" In one example, the analysis of bioavailability data of an extended-release formulation, as well as the mean dissolution times estimated in vivo and in vitro with the use of the inverse Gaussian function, is well in accordance, suggesting that the inverse Gaussian function indeed accounts for the in vivo dissolution process."1.35A note on population analysis of dissolution-absorption models using the inverse Gaussian function. ( D'Argenio, DZ; Wang, J; Weiss, M, 2008)
"Trapidil was administered intravenously as a 100-mg bolus."1.29Pharmacokinetics of trapidil in patients with chronic liver disease. ( Berndt, A; Looby, M; Pönicke, K; Weiss, M; Zipprich, B, 1996)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, J1
Weiss, M3
D'Argenio, DZ1
Berndt, A2
Looby, M1
Pönicke, K2
Zipprich, B1

Trials

1 trial available for trapidil and Liver Dysfunction

ArticleYear
Pharmacokinetics of trapidil (Rocornal) in patients with chronic liver disease.
    International journal of clinical pharmacology, therapy, and toxicology, 1992, Volume: 30, Issue:11

    Topics: Chromatography, High Pressure Liquid; Chronic Disease; Female; Humans; Liver Cirrhosis; Liver Diseas

1992

Other Studies

2 other studies available for trapidil and Liver Dysfunction

ArticleYear
A note on population analysis of dissolution-absorption models using the inverse Gaussian function.
    Journal of clinical pharmacology, 2008, Volume: 48, Issue:6

    Topics: Algorithms; Biological Availability; Delayed-Action Preparations; Humans; Liver Diseases; Models, Bi

2008
Pharmacokinetics of trapidil in patients with chronic liver disease.
    Journal of clinical pharmacology, 1996, Volume: 36, Issue:10

    Topics: Adult; Aged; Biological Availability; Chromatography, High Pressure Liquid; Chronic Disease; Confide

1996