trapidil and Glioma
trapidil has been researched along with Glioma in 3 studies
Trapidil: A coronary vasodilator agent.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trapidil is a PDGF antagonist that can inhibit the proliferation of the PDGF-producing glioma cells, U251MG." | 7.69 | The mechanism of growth-regulation of glioma cells by trapidil. ( Kuratsu, J; Morioka, M; Saitoh, Y; Sato, K; Takeshima, H; Ushio, Y, 1995) |
| "Trapidil is a PDGF antagonist that can inhibit the proliferation of the PDGF-producing glioma cells, U251MG." | 3.69 | The mechanism of growth-regulation of glioma cells by trapidil. ( Kuratsu, J; Morioka, M; Saitoh, Y; Sato, K; Takeshima, H; Ushio, Y, 1995) |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Kuratsu, J | 3 |
| Sato, K | 1 |
| Saitoh, Y | 1 |
| Takeshima, H | 1 |
| Morioka, M | 1 |
| Ushio, Y | 3 |
Other Studies
3 other studies available for trapidil and Glioma
| Article | Year |
|---|---|
The mechanism of growth-regulation of glioma cells by trapidil.
Topics: Blotting, Northern; Brain Neoplasms; Cell Cycle; Enzyme Activation; Gene Expression Regulation, Neop | 1995 |
[Microbiological approach to the treatment of brain tumors].
Topics: Brain Neoplasms; Epidermal Growth Factor; Fibroblast Growth Factors; Glioma; Humans; Oncogenes; Plat | 1991 |
Antiproliferative effect of trapidil, a platelet-derived growth factor antagonist, on a glioma cell line in vitro.
Topics: Animals; Glioma; Nimustine; Platelet-Derived Growth Factor; Pyrimidines; Suramin; Time Factors; Trap | 1990 |