trapidil has been researched along with Disease Models, Animal in 15 studies
Trapidil: A coronary vasodilator agent.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of trapidil on experimental hyperlipemia and atherosclerosis induced by 1% cholesterol diet in SPF male rabbits (JW/KBL) was investigated by the determination of the lipid contents of the plasma and thoracic aorta and examination of morphological changes in the aorta." | 7.66 | [Effect of trapidil on experimental hyperlipemia and atherosclerosis induced by cholesterol diet in SPF Japanese white rabbits]. ( Gotoh, H; Nakayama, S; Sakamoto, K; Tonooka, M, 1983) |
| "Trapidil increases the isoprenalin-induced necrosis of the myocardium in the rat." | 7.65 | [Modification of the isoprenaline-induced myocardial necrosis using trapidil]. ( Lampe, D; Lange, B; Mai, I, 1976) |
| "The effect of trapidil on experimental hyperlipemia and atherosclerosis induced by 1% cholesterol diet in SPF male rabbits (JW/KBL) was investigated by the determination of the lipid contents of the plasma and thoracic aorta and examination of morphological changes in the aorta." | 3.66 | [Effect of trapidil on experimental hyperlipemia and atherosclerosis induced by cholesterol diet in SPF Japanese white rabbits]. ( Gotoh, H; Nakayama, S; Sakamoto, K; Tonooka, M, 1983) |
| "Trapidil increases the isoprenalin-induced necrosis of the myocardium in the rat." | 3.65 | [Modification of the isoprenaline-induced myocardial necrosis using trapidil]. ( Lampe, D; Lange, B; Mai, I, 1976) |
| "Trapidil has been described to improve the redox balance and cardiac conditions." | 1.48 | Trapidil improves hemodynamic, echocardiographic and redox state parameters of right ventricle in monocrotaline-induced pulmonary arterial hypertension model. ( Belló-Klein, A; Carraro, CC; Colombo, R; da Rosa Araujo, AS; de Lima-Seolin, BG; Lacerda, DS; Poletto Bonetto, JH; Schenkel, PC; Teixeira, RB; Türck, P, 2018) |
| "After subarachnoid hemorrhage (SAH), platelet-derived growth factor-BB (PDGF-BB) is secreted in and around the cerebral arteries." | 1.36 | Platelet-derived growth factor-induced severe and chronic vasoconstriction of cerebral arteries: proposed growth factor explanation of cerebral vasospasm. ( Iihara, K; Kikuchi, H; Miyamoto, S; Nagata, I; Nakajo, Y; Xue, JH; Yanamoto, H; Zhang, ZW, 2010) |
| "Trapidil treatment either before or after hypoxia results in significant reduction of the numbers of apoptotic cells in both hemispheres, when it is compared with saline treatment group." | 1.35 | The role of trapidil on neuronal apoptosis in neonatal rat model of hypoxic ischemic brain injury. ( Atici, A; Bozlu, G; Nayci, A; Okuyaz, C; Polat, A; Taskinlar, H; Turhan, AH, 2008) |
| "Trapidil treatment groups were administrated a single dose of trapidil (8 mg/kg) intraperitoneally just after the injury." | 1.34 | Effects of low dose trapidil on electrical properties of a rat peripheral nerve after crush injury. ( Büyükakilli, B; Güneş, S; Taşdelen, B, 2007) |
| "Trapidil was shown to have a clear spasmolytic effect on the rabbit's basilar artery." | 1.31 | Resolution of cerebral vasospasm with trapidil; an animal model. ( Bagdatoglu, C; Berk, C; Egemen, N; Guleryuz, A; Kanik, A; Koksel, T; Ozdemir, C; Unlu, A, 2002) |
| "Trapidil was expected to be an effective antithrombotic agent." | 1.26 | Antithrombotic activity and the mechanism of action of trapidil (Rocornal). ( Kitamura, Y; Ohnishi, H; Shimada, S; Suzuki, Y; Yamaguchi, K, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (26.67) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Türck, P | 1 |
| Lacerda, DS | 1 |
| Carraro, CC | 1 |
| de Lima-Seolin, BG | 1 |
| Teixeira, RB | 1 |
| Poletto Bonetto, JH | 1 |
| Colombo, R | 1 |
| Schenkel, PC | 1 |
| Belló-Klein, A | 1 |
| da Rosa Araujo, AS | 1 |
| Zhang, ZW | 1 |
| Yanamoto, H | 1 |
| Nagata, I | 1 |
| Miyamoto, S | 1 |
| Nakajo, Y | 1 |
| Xue, JH | 1 |
| Iihara, K | 1 |
| Kikuchi, H | 1 |
| Bagdatoglu, C | 1 |
| Guleryuz, A | 1 |
| Unlu, A | 1 |
| Kanik, A | 1 |
| Berk, C | 1 |
| Ozdemir, C | 1 |
| Koksel, T | 1 |
| Egemen, N | 1 |
| Somuncu, S | 1 |
| Cakmak, M | 1 |
| Erdogan, S | 1 |
| Caglayan, O | 1 |
| Akman, H | 1 |
| Kaya, M | 2 |
| Vowinkel, T | 1 |
| Anthoni, C | 1 |
| Wood, KC | 1 |
| Stokes, KY | 1 |
| Russell, J | 1 |
| Gray, L | 1 |
| Bharwani, S | 1 |
| Senninger, N | 1 |
| Alexander, JS | 1 |
| Krieglstein, CF | 1 |
| Grisham, MB | 1 |
| Granger, DN | 1 |
| Atici, A | 1 |
| Bozlu, G | 1 |
| Turhan, AH | 1 |
| Polat, A | 1 |
| Nayci, A | 1 |
| Okuyaz, C | 1 |
| Taskinlar, H | 1 |
| Büyükakilli, B | 1 |
| Taşdelen, B | 1 |
| Güneş, S | 1 |
| Gotoh, H | 1 |
| Tonooka, M | 1 |
| Nakayama, S | 1 |
| Sakamoto, K | 1 |
| Suzuki, Y | 1 |
| Yamaguchi, K | 1 |
| Shimada, S | 1 |
| Kitamura, Y | 1 |
| Ohnishi, H | 1 |
| Saunders, RN | 1 |
| Matsuno, H | 1 |
| Stassen, JM | 1 |
| Hoylaerts, MF | 1 |
| Vermylen, J | 1 |
| Deckmyn, H | 1 |
| Göçer, AI | 1 |
| Ildan, F | 1 |
| Tuna, M | 1 |
| Polat, S | 1 |
| Tamer, L | 1 |
| Erman, T | 1 |
| Mai, I | 1 |
| Lampe, D | 1 |
| Lange, B | 1 |
| Karas, SP | 1 |
| Santoian, EC | 1 |
| Gravanis, MB | 1 |
2 reviews available for trapidil and Disease Models, Animal
| Article | Year |
|---|---|
Evaluation of platelet-inhibiting drugs in models of atherosclerosis.
Topics: Animals; Arteriosclerosis; Aspirin; Blood Platelets; Cell Division; Disease Models, Animal; Drug Eva | 1982 |
Restenosis following coronary angioplasty.
Topics: Angioplasty, Balloon, Coronary; Animals; Coronary Angiography; Coronary Disease; Disease Models, Ani | 1991 |
13 other studies available for trapidil and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Trapidil improves hemodynamic, echocardiographic and redox state parameters of right ventricle in monocrotaline-induced pulmonary arterial hypertension model.
Topics: Animals; Blood Pressure; Calcium; Cardiac Catheterization; Cardiomegaly; Disease Models, Animal; Ech | 2018 |
Platelet-derived growth factor-induced severe and chronic vasoconstriction of cerebral arteries: proposed growth factor explanation of cerebral vasospasm.
Topics: Animals; Cerebral Angiography; Cerebral Arteries; Disease Models, Animal; Dose-Response Relationship | 2010 |
Resolution of cerebral vasospasm with trapidil; an animal model.
Topics: Animals; Basilar Artery; Disease Models, Animal; Female; Male; Platelet Aggregation Inhibitors; Rabb | 2002 |
Protective effects of trapidil in ischemia-reperfusion injury due to testicular torsion and detorsion: an experimental study.
Topics: Animals; Disease Models, Animal; Male; Malondialdehyde; Nitric Oxide; Rats; Rats, Wistar; Reperfusio | 2006 |
CD40-CD40 ligand mediates the recruitment of leukocytes and platelets in the inflamed murine colon.
Topics: Animals; Blood Platelets; CD40 Antigens; CD40 Ligand; Cell Adhesion; Chemotaxis, Leukocyte; Colitis; | 2007 |
The role of trapidil on neuronal apoptosis in neonatal rat model of hypoxic ischemic brain injury.
Topics: Animals; Animals, Newborn; Apoptosis; Caspase 3; Cell Count; Disease Models, Animal; Female; Hypoxia | 2008 |
Effects of low dose trapidil on electrical properties of a rat peripheral nerve after crush injury.
Topics: Animals; Disease Models, Animal; Electrophysiology; Female; Injections, Intraperitoneal; Nerve Crush | 2007 |
[Effect of trapidil on experimental hyperlipemia and atherosclerosis induced by cholesterol diet in SPF Japanese white rabbits].
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Cholesterol, Dietary; Diet, Atherogenic; Disease Models, | 1983 |
Antithrombotic activity and the mechanism of action of trapidil (Rocornal).
Topics: Adenosine Triphosphate; Animals; Aspirin; Blood Coagulation; Blood Platelets; Dipyridamole; Disease | 1982 |
Fast and reproducible vascular neointima formation in the hamster carotid artery: effects of trapidil and captopril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Carotid Stenosis; Cell Division; Crice | 1995 |
Effects of trapidil on ATPase, lipid peroxidation, and correlation with ultrastructure in experimental spinal cord injury.
Topics: Adenosine Triphosphatases; Animals; Disease Models, Animal; Laminectomy; Lipid Peroxidation; Male; M | 2001 |
[Modification of the isoprenaline-induced myocardial necrosis using trapidil].
Topics: Animals; Cardiomyopathies; Disease Models, Animal; Isoproterenol; Male; Myocardial Infarction; Necro | 1976 |