trapidil has been researched along with Coronary Disease in 21 studies
Trapidil: A coronary vasodilator agent.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was carried out to investigate exercise test results and the outcome of the quality of life after administration of trapidil (CAS 15421-84-8, Rocornal) or nifedipine (CAS 21829-25-4) to patients with coronary heart disease." | 9.08 | [The effects of treatment with trapidil compared to nifedipine on physical, emotional and cognitive exercise tolerance in patients with coronary heart disease]. ( Assmann, I; Burkard, G; Lehrl, S; Strösser, W, 1996) |
| "The present study was carried out to investigate exercise test results and the outcome of the quality of life after administration of trapidil (CAS 15421-84-8, Rocornal) or nifedipine (CAS 21829-25-4) to patients with coronary heart disease." | 5.08 | [The effects of treatment with trapidil compared to nifedipine on physical, emotional and cognitive exercise tolerance in patients with coronary heart disease]. ( Assmann, I; Burkard, G; Lehrl, S; Strösser, W, 1996) |
| " Trapidil significantly increased the amount of aconitine or ouabain needed for production of ventricular arrhythmias in rats and guinea pigs." | 3.66 | Possible antiarrhythmic activities of trapidil. ( Akiyoshi, R; Itoh, C; Kitamura, Y; Niho, T; Ohnishi, H; Sakanashi, M; Yoshikawa, Y, 1983) |
| "The acute effects of intravenous trapidil on hemodynamics, coronary circulation and myocardial metabolism were evaluated in 19 patients (Group I: 10 patients of chest pain syndrome; Group II: 9 patients of coronary heart disease)." | 3.66 | Acute effects of intravenous trapidil on hemodynamics, coronary circulation and myocardial metabolism in man. ( Hori, M; Inoue, M; Ishikawa, K; Kodama, K; Koretsune, Y; Mishima, M; Nanto, S; Taniura, K, 1983) |
| "Trapidil is an antiplatelet drug with specific platelet-derived growth factor antagonism and antiproliferative effects in the rat and rabbit models after balloon angioplasty." | 2.67 | Trapidil (triazolopyrimidine), a platelet-derived growth factor antagonist, reduces restenosis after percutaneous transluminal coronary angioplasty. Results of the randomized, double-blind STARC study. Studio Trapidil versus Aspirin nella Restenosi Corona ( Balducelli, M; Cantini, L; Casari, A; Chioin, R; De Servi, S; Fabbri, M; Fontanelli, A; Maresta, A; Monici Preti, PA; Repetto, S, 1994) |
| "Thus trapidil was useful in preventing intimal proliferation after PTCA, especially in patients with more than 30% residual stenosis after PTCA." | 2.67 | Effects of trapidil (triazolopyrimidine), a platelet-derived growth factor antagonist, in preventing restenosis after percutaneous transluminal coronary angioplasty. ( Inden, M; Konishi, T; Nakano, T; Okamoto, S; Setsuda, M, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (42.86) | 18.7374 |
| 1990's | 9 (42.86) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, M | 1 |
| Mhulláin, FN | 1 |
| Nolan, M | 1 |
| Kitai, T | 1 |
| Ishiwata, S | 1 |
| Yamaguchi, T | 1 |
| Inoue, T | 1 |
| Ito, T | 1 |
| Su, K | 1 |
| Sada, T | 1 |
| Amano, N | 1 |
| Naito, A | 1 |
| Oka, Y | 1 |
| Okabe, F | 1 |
| Sekine, I | 1 |
| Matsumoto, S | 1 |
| Sakanashi, M | 1 |
| Yoshikawa, Y | 1 |
| Akiyoshi, R | 1 |
| Itoh, C | 1 |
| Kitamura, Y | 1 |
| Niho, T | 1 |
| Ohnishi, H | 2 |
| Koretsune, Y | 1 |
| Kodama, K | 1 |
| Nanto, S | 1 |
| Ishikawa, K | 1 |
| Taniura, K | 1 |
| Mishima, M | 1 |
| Hori, M | 1 |
| Inoue, M | 1 |
| Kosuzume, H | 1 |
| Hayashi, Y | 1 |
| Yamaguchi, K | 1 |
| Suzuki, Y | 1 |
| Itoh, R | 1 |
| Takahashi, M | 1 |
| Sasayama, S | 1 |
| Nakamura, M | 1 |
| Hirose, K | 1 |
| Kawai, C | 1 |
| Lohr, E | 1 |
| Maresta, A | 2 |
| Balducelli, M | 2 |
| Cantini, L | 2 |
| Casari, A | 2 |
| Chioin, R | 2 |
| Fabbri, M | 1 |
| Fontanelli, A | 2 |
| Monici Preti, PA | 2 |
| Repetto, S | 2 |
| De Servi, S | 1 |
| Assmann, I | 1 |
| Lehrl, S | 1 |
| Burkard, G | 1 |
| Strösser, W | 1 |
| Raffaghello, S | 1 |
| Galassi, AR | 1 |
| Tamburino, C | 1 |
| Nicosia, A | 1 |
| Russo, G | 1 |
| Grassi, R | 1 |
| Monaco, A | 1 |
| Giuffrida, G | 1 |
| von Hodenberg, E | 1 |
| Tost, B | 1 |
| Scheffold, T | 1 |
| Okamoto, S | 1 |
| Inden, M | 1 |
| Setsuda, M | 1 |
| Konishi, T | 1 |
| Nakano, T | 1 |
| Kurita, A | 1 |
| Satomura, K | 1 |
| Kawaguchi, S | 1 |
| Takase, B | 1 |
| Shibuya, T | 1 |
| Arakawa, K | 1 |
| Mizuno, K | 1 |
| Sugawara, H | 1 |
| Isojima, K | 1 |
| Karas, SP | 1 |
| Santoian, EC | 1 |
| Gravanis, MB | 1 |
| Beitz, A | 1 |
| Taube, C | 1 |
| Beitz, J | 1 |
| Goos, H | 1 |
| Graff, J | 1 |
| Nohring, J | 1 |
| Lindenau, KF | 1 |
| Mest, HJ | 3 |
| Mentz, P | 1 |
| Pawelski, KE | 1 |
| Giessler, C | 1 |
| Mannes, F | 1 |
| Rotzoll, S | 1 |
| Thomas, E | 1 |
3 reviews available for trapidil and Coronary Disease
| Article | Year |
|---|---|
Intrepide; Trapidil eluting stent.
Topics: Angioplasty, Balloon, Coronary; Animals; Coronary Disease; Coronary Restenosis; Drug-Eluting Stents; | 2008 |
[Prevention of postangioplasty restenosis].
Topics: Angioplasty, Balloon, Coronary; Atherectomy, Coronary; Clinical Trials as Topic; Coated Materials, B | 2003 |
Restenosis following coronary angioplasty.
Topics: Angioplasty, Balloon, Coronary; Animals; Coronary Angiography; Coronary Disease; Disease Models, Ani | 1991 |
5 trials available for trapidil and Coronary Disease
| Article | Year |
|---|---|
Trapidil (triazolopyrimidine), a platelet-derived growth factor antagonist, reduces restenosis after percutaneous transluminal coronary angioplasty. Results of the randomized, double-blind STARC study. Studio Trapidil versus Aspirin nella Restenosi Corona
Topics: Aged; Angioplasty, Balloon, Coronary; Coronary Angiography; Coronary Disease; Double-Blind Method; F | 1994 |
[The effects of treatment with trapidil compared to nifedipine on physical, emotional and cognitive exercise tolerance in patients with coronary heart disease].
Topics: Aged; Cognition; Coronary Disease; Double-Blind Method; Electrocardiography; Emotions; Exercise; Exe | 1996 |
The trapidil restenosis trial (STARC study): background, methods and clinical characteristics of the patient population.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clinical Protocols; Cohort Studies; Coronary D | 1994 |
A randomized comparison of trapidil (triazolopyrimidine), a platelet-derived growth factor antagonist, versus aspirin in prevention of angiographic restenosis after coronary artery Palmaz-Schatz stent implantation.
Topics: Aged; Aspirin; Coronary Angiography; Coronary Disease; Double-Blind Method; Female; Humans; Male; Mi | 1999 |
Effects of trapidil (triazolopyrimidine), a platelet-derived growth factor antagonist, in preventing restenosis after percutaneous transluminal coronary angioplasty.
Topics: Angioplasty, Balloon, Coronary; Coronary Angiography; Coronary Disease; Humans; Platelet-Derived Gro | 1992 |
13 other studies available for trapidil and Coronary Disease
| Article | Year |
|---|---|
[Blood thromboxane A2 and prostaglandin I2 levels and platelet phospholipid fatty acid composition ratios in ischemic heart disease and cerebral infarction--with special reference to the effect of antiplatelet agents].
Topics: Aged; Aspirin; Blood Platelets; Cerebral Infarction; Coronary Disease; Dipyridamole; Epoprostenol; F | 1983 |
[Combined effects of propranolol and trapidil on ischemic heart disease--exercise tolerance and cardiac function].
Topics: Coronary Disease; Drug Therapy, Combination; Female; Heart; Humans; Male; Middle Aged; Physical Exer | 1983 |
Possible antiarrhythmic activities of trapidil.
Topics: Aconitine; Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Diseas | 1983 |
Acute effects of intravenous trapidil on hemodynamics, coronary circulation and myocardial metabolism in man.
Topics: Aged; Coronary Circulation; Coronary Disease; Female; Hemodynamics; Humans; Infusions, Parenteral; M | 1983 |
Effects of trapidil on thromboxane A2-induced aggregation of platelets, ischemic changes in heart and biosynthesis of thromboxane A2.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Cholesterol; Coronary Disease; Lipoproteins, | 1981 |
Effect of trapidil on regional myocardial function during acute coronary occlusion in the dog.
Topics: Acute Disease; Animals; Chemical Phenomena; Chemistry; Coronary Disease; Dogs; Female; Heart; Hemody | 1982 |
[Therapy of ischemic heart disease with Trapidil. Observations with 4,014 patients in medical practice].
Topics: Angina Pectoris; Coronary Disease; Drug Approval; Follow-Up Studies; Germany; Humans; Trapidil; Trea | 1994 |
[New strategies in the treatment of restenosis].
Topics: Angioplasty, Balloon, Coronary; Angioplasty, Balloon, Laser-Assisted; Anticholesteremic Agents; Athe | 2000 |
[Trapidil--a new alternative in ischemic heart disease. Report from the International Trapidil Workshop. Munich, 28-29 June 1991].
Topics: Coronary Disease; Humans; Trapidil | 1992 |
The effects of trapidil on left ventricular function and platelet aggregation in patients with coronary artery disease subjected to pacing.
Topics: Aged; beta-Thromboglobulin; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Disease; Epin | 1991 |
Influence of drugs on the TXA2/PGI2 balance and on the atherogenic index in myocardial ischemia in dogs.
Topics: Animals; Antihypertensive Agents; Arteriosclerosis; Biomarkers; Coronary Disease; Dogs; Epoprostenol | 1988 |
Myocardial biosynthesis of prostacyclin and the influence of cardiac loading and drugs.
Topics: Animals; Aortic Valve Stenosis; Caffeine; Coronary Disease; Epoprostenol; Guinea Pigs; Heart; Heart | 1988 |
[Is there a renaissance for trapidil?].
Topics: Angina Pectoris; Animals; Arterial Occlusive Diseases; Coronary Circulation; Coronary Disease; Human | 1986 |