trapidil has been researched along with Cardiovascular Stroke in 9 studies
Trapidil: A coronary vasodilator agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A large-scale study was conducted to assess the effect of long-term administration of trapidil on the prognosis of patients with angiographic evidence of coronary artery disease (CAD)." | 9.10 | Effect of trapidil on cardiovascular events in patients with coronary artery disease (results from the Japan Multicenter Investigation for Cardiovascular Diseases-Mochida [JMIC-M]). ( Hirayama, A; Hosoda, S; Kawai, C; Kodama, K; Nonogi, H; Origasa, H; Sumiyoshi, T; Yui, Y, 2003) |
| "Aspirin therapy confers conclusive net benefits in the acute phase of evolving myocardial infarction, but no clear evidence of benefit from the long-term use of aspirin after acute myocardial infarction (AMI) has been shown in any single study." | 9.09 | Effects of aspirin and trapidil on cardiovascular events after acute myocardial infarction. Japanese Antiplatelets Myocardial Infarction Study (JAMIS) Investigators. ( Hattori, R; Ishikawa, K; Masuda, Y; Miyazaki, S; Motomiya, T; Ogawa, H; Saito, M; Tamura, Y; Tanaka, H; Yamaguchi, T; Yasue, H, 1999) |
| "Trapidil increases the isoprenalin-induced necrosis of the myocardium in the rat." | 7.65 | [Modification of the isoprenaline-induced myocardial necrosis using trapidil]. ( Lampe, D; Lange, B; Mai, I, 1976) |
| "A large-scale study was conducted to assess the effect of long-term administration of trapidil on the prognosis of patients with angiographic evidence of coronary artery disease (CAD)." | 5.10 | Effect of trapidil on cardiovascular events in patients with coronary artery disease (results from the Japan Multicenter Investigation for Cardiovascular Diseases-Mochida [JMIC-M]). ( Hirayama, A; Hosoda, S; Kawai, C; Kodama, K; Nonogi, H; Origasa, H; Sumiyoshi, T; Yui, Y, 2003) |
| "Aspirin therapy confers conclusive net benefits in the acute phase of evolving myocardial infarction, but no clear evidence of benefit from the long-term use of aspirin after acute myocardial infarction (AMI) has been shown in any single study." | 5.09 | Effects of aspirin and trapidil on cardiovascular events after acute myocardial infarction. Japanese Antiplatelets Myocardial Infarction Study (JAMIS) Investigators. ( Hattori, R; Ishikawa, K; Masuda, Y; Miyazaki, S; Motomiya, T; Ogawa, H; Saito, M; Tamura, Y; Tanaka, H; Yamaguchi, T; Yasue, H, 1999) |
| " Based on this concept, we have performed several large-scale clinical trials to provide EBM, including the Japanese Antiplatelets Myocardial Infarction Study [JAMIS; clinical improvement in acute myocardial infarction (AMI) patients with antiplatelet therapy], the Japanese beta-Blockers and Calcium Antagonists Myocardial Infarction (JBCMI; comparison of the effects of beta-blockers and calcium antagonists on cardiovascular events in post-AMI patients), a multicenter study for aggressive lipid-lowering strategy by HMG-CoA reductase inhibitors in patients with AMI (MUSASHI; effects of statin therapy on cardiovascular events in patients with AMI), and the Japanese Primary Prevention of Atherosclerosis with Aspirin for Diabetes (JPAD trial; efficacy of low-dose aspirin therapy for primary prevention of atherosclerotic events in type 2 diabetic patients)." | 4.85 | Clinical evidence for Japanese population based on prospective studies--linking clinical trials and clinical practice. ( Kojima, S; Ogawa, H, 2009) |
| "Trapidil increases the isoprenalin-induced necrosis of the myocardium in the rat." | 3.65 | [Modification of the isoprenaline-induced myocardial necrosis using trapidil]. ( Lampe, D; Lange, B; Mai, I, 1976) |
| " The dose-response curve of TM was parallel to that of nitroglycerin and papaverine and steeper than that of dipyridamol or adenosine." | 1.25 | [Pharmacology of cornary dilator agent, trapymin. (2) Analysis of its mode of action]. ( Ogawa, N; Ohnishi, H; Tsukuda, S; Yamaguchi, K, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ogawa, H | 2 |
| Kojima, S | 1 |
| Sirbu, V | 1 |
| Musumeci, G | 1 |
| Fiocca, L | 1 |
| Vassileva, A | 1 |
| Rossini, R | 1 |
| Lortkipanidze, N | 1 |
| Matiashvili, A | 1 |
| Mihalcsik, L | 1 |
| Gavazzi, A | 1 |
| Valsecchi, O | 1 |
| Guagliumi, G | 1 |
| Hirayama, A | 1 |
| Kodama, K | 1 |
| Yui, Y | 1 |
| Nonogi, H | 1 |
| Sumiyoshi, T | 1 |
| Origasa, H | 1 |
| Hosoda, S | 1 |
| Kawai, C | 1 |
| Ishikawa, H | 1 |
| Kagoshima, T | 1 |
| Sakamoto, S | 1 |
| Ohtsuka, F | 1 |
| Yabuta, M | 1 |
| Nonaka, H | 1 |
| Yasue, H | 1 |
| Tanaka, H | 1 |
| Miyazaki, S | 1 |
| Hattori, R | 1 |
| Saito, M | 1 |
| Ishikawa, K | 1 |
| Masuda, Y | 1 |
| Yamaguchi, T | 1 |
| Motomiya, T | 1 |
| Tamura, Y | 1 |
| Mai, I | 1 |
| Lampe, D | 1 |
| Lange, B | 1 |
| Ohnishi, H | 1 |
| Tsukuda, S | 1 |
| Yamaguchi, K | 1 |
| Ogawa, N | 1 |
| Lu, XA | 1 |
| Ling, H | 1 |
| Dong, CR | 1 |
| Ouyang, JP | 1 |
| Mest, HJ | 1 |
| Thomas, E | 1 |
1 review available for trapidil and Cardiovascular Stroke
| Article | Year |
|---|---|
Clinical evidence for Japanese population based on prospective studies--linking clinical trials and clinical practice.
Topics: Adrenergic beta-Antagonists; Aged; Asian People; Aspirin; Atherosclerosis; Calcium Channel Blockers; | 2009 |
2 trials available for trapidil and Cardiovascular Stroke
| Article | Year |
|---|---|
Effect of trapidil on cardiovascular events in patients with coronary artery disease (results from the Japan Multicenter Investigation for Cardiovascular Diseases-Mochida [JMIC-M]).
Topics: Angina Pectoris; Coronary Artery Disease; Death; Female; Follow-Up Studies; Heart Failure; Hospitali | 2003 |
Effects of aspirin and trapidil on cardiovascular events after acute myocardial infarction. Japanese Antiplatelets Myocardial Infarction Study (JAMIS) Investigators.
Topics: Aged; Angina, Unstable; Aspirin; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation I | 1999 |
6 other studies available for trapidil and Cardiovascular Stroke
| Article | Year |
|---|---|
Optical coherence tomography in ST-elevation myocardial infarction treated with novel drug-eluting stent: preprocedural, postimplant and 2-month follow-up findings.
Topics: Coronary Angiography; Coronary Vessels; Drug-Eluting Stents; Echocardiography; Follow-Up Studies; Hu | 2011 |
[Effects and limitations of vasodilator agents-trapidil and other smooth muscle relaxant].
Topics: Hemodynamics; Humans; Male; Middle Aged; Muscle, Smooth, Vascular; Myocardial Infarction; Parasympat | 1983 |
[Modification of the isoprenaline-induced myocardial necrosis using trapidil].
Topics: Animals; Cardiomyopathies; Disease Models, Animal; Isoproterenol; Male; Myocardial Infarction; Necro | 1976 |
[Pharmacology of cornary dilator agent, trapymin. (2) Analysis of its mode of action].
Topics: Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Blood Glucose; Calcium Chloride; Catecholamin | 1975 |
The effects of trapidil and propranolol on platelet aggregation and prostacyclin-thromboxane balance following acute myocardial infarction in rabbits.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Female; Male; Myocardial Infarction; Platelet Aggregation; Pr | 1988 |
[Is there a renaissance for trapidil?].
Topics: Angina Pectoris; Animals; Arterial Occlusive Diseases; Coronary Circulation; Coronary Disease; Human | 1986 |