trapidil has been researched along with Brain Ischemia in 3 studies
Trapidil: A coronary vasodilator agent.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The experimental study presented was undertaken to evaluate the role of thromboxane A2 contributing to aggravating cerebral ischemia, and to examine the effect of a thromboxane A2 synthetase inhibitor, trapidil on cerebral ischemia." | 7.67 | [Protective effect of thromboxane A2 synthetase inhibitor (trapidil) on acutely-induced cerebral ischemia]. ( Katayama, Y; Memezawa, H; Minamisawa, H; Shimizu, J; Sugimoto, S; Suzuki, S; Terashi, A, 1986) |
| "Cerebral ischemia was produced using bilateral common carotid artery occlusion in spontaneously hypertensive rats." | 5.28 | Role of arachidonic acid metabolism on ischemic brain edema and metabolism. ( Kamiya, T; Kashiwagi, F; Katayama, Y; Memezawa, H; Shimizu, J; Suzuki, S; Terashi, A, 1990) |
| "The experimental study presented was undertaken to evaluate the role of thromboxane A2 contributing to aggravating cerebral ischemia, and to examine the effect of a thromboxane A2 synthetase inhibitor, trapidil on cerebral ischemia." | 3.67 | [Protective effect of thromboxane A2 synthetase inhibitor (trapidil) on acutely-induced cerebral ischemia]. ( Katayama, Y; Memezawa, H; Minamisawa, H; Shimizu, J; Sugimoto, S; Suzuki, S; Terashi, A, 1986) |
| "Trapidil has shown a more complete antithrombocytic activity than other antiaggregating drugs; as a matter of fact it inhibits the formation of TXA2 through a mechanism of receptorial antagonism and at the same time it favours an increase of prostacyclina from the arterial walls." | 2.38 | [Trapidil after one year]. ( Agus, GB, 1993) |
| "Cerebral ischemia was produced using bilateral common carotid artery occlusion in spontaneously hypertensive rats." | 1.28 | Role of arachidonic acid metabolism on ischemic brain edema and metabolism. ( Kamiya, T; Kashiwagi, F; Katayama, Y; Memezawa, H; Shimizu, J; Suzuki, S; Terashi, A, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Agus, GB | 1 |
| Katayama, Y | 2 |
| Shimizu, J | 2 |
| Suzuki, S | 2 |
| Memezawa, H | 2 |
| Kashiwagi, F | 1 |
| Kamiya, T | 1 |
| Terashi, A | 2 |
| Minamisawa, H | 1 |
| Sugimoto, S | 1 |
1 review available for trapidil and Brain Ischemia
| Article | Year |
|---|---|
[Trapidil after one year].
Topics: Anticoagulants; Arm; Arteriosclerosis; Brain Ischemia; Clinical Trials as Topic; Drug Evaluation; Hu | 1993 |
2 other studies available for trapidil and Brain Ischemia
| Article | Year |
|---|---|
Role of arachidonic acid metabolism on ischemic brain edema and metabolism.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brain Chemistry; Brain Edema; Brain Ischemia; Energy M | 1990 |
[Protective effect of thromboxane A2 synthetase inhibitor (trapidil) on acutely-induced cerebral ischemia].
Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Cerebral Arteries; Lactates; Lactic Acid; Ma | 1986 |