trapidil has been researched along with Arteriosclerosis in 12 studies
Trapidil: A coronary vasodilator agent.
Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of trapidil on experimental hyperlipemia and atherosclerosis induced by 1% cholesterol diet in SPF male rabbits (JW/KBL) was investigated by the determination of the lipid contents of the plasma and thoracic aorta and examination of morphological changes in the aorta." | 7.66 | [Effect of trapidil on experimental hyperlipemia and atherosclerosis induced by cholesterol diet in SPF Japanese white rabbits]. ( Gotoh, H; Nakayama, S; Sakamoto, K; Tonooka, M, 1983) |
| "The effect of trapidil on experimental hyperlipemia and atherosclerosis induced by 1% cholesterol diet in SPF male rabbits (JW/KBL) was investigated by the determination of the lipid contents of the plasma and thoracic aorta and examination of morphological changes in the aorta." | 3.66 | [Effect of trapidil on experimental hyperlipemia and atherosclerosis induced by cholesterol diet in SPF Japanese white rabbits]. ( Gotoh, H; Nakayama, S; Sakamoto, K; Tonooka, M, 1983) |
| "Trapidil has shown a more complete antithrombocytic activity than other antiaggregating drugs; as a matter of fact it inhibits the formation of TXA2 through a mechanism of receptorial antagonism and at the same time it favours an increase of prostacyclina from the arterial walls." | 2.38 | [Trapidil after one year]. ( Agus, GB, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gotoh, H | 1 |
| Tonooka, M | 1 |
| Nakayama, S | 1 |
| Sakamoto, K | 1 |
| Ohnishi, H | 2 |
| Yamaguchi, K | 2 |
| Shimada, S | 2 |
| Suzuki, Y | 2 |
| Kumagai, A | 2 |
| Saunders, RN | 1 |
| Sato, M | 1 |
| Funatc, H | 1 |
| Katsuki, Y | 1 |
| Dabasaki, T | 1 |
| Saitoh, Y | 1 |
| Bonfardeci, G | 1 |
| Cimminiello, C | 1 |
| Cantini, L | 1 |
| Arpaia, G | 1 |
| Aloisio, M | 1 |
| Pozzi, F | 1 |
| Sakata, N | 1 |
| Fujimitsu, K | 1 |
| Jimi, S | 1 |
| Takebayashi, S | 1 |
| Agus, GB | 1 |
| Kato, Y | 1 |
| Tsuda, T | 1 |
| Hosaka, Y | 1 |
| Takahashi, T | 1 |
| Shirakawa, K | 1 |
| Furusako, S | 1 |
| Mizuguchi, K | 1 |
| Mochizuki, H | 1 |
| Beitz, J | 2 |
| Krüger, J | 1 |
| Beitz, A | 2 |
| Pawelski, K | 1 |
| Szymanski, C | 1 |
| Rath, FW | 1 |
| Mest, HJ | 3 |
| Liu, MW | 1 |
| Roubin, GS | 1 |
| Robinson, KA | 1 |
| Black, AJ | 1 |
| Hearn, JA | 1 |
| Siegel, RJ | 1 |
| King, SB | 1 |
| Taube, C | 1 |
| Goos, H | 1 |
| Graff, J | 1 |
| Nohring, J | 1 |
| Lindenau, KF | 1 |
| Giessler, C | 1 |
| Fahr, A | 1 |
| Tertov, VV | 1 |
| Kudryashov, SA | 1 |
| Orekhov, AN | 1 |
| Smirnov, VN | 1 |
2 reviews available for trapidil and Arteriosclerosis
| Article | Year |
|---|---|
Evaluation of platelet-inhibiting drugs in models of atherosclerosis.
Topics: Animals; Arteriosclerosis; Aspirin; Blood Platelets; Cell Division; Disease Models, Animal; Drug Eva | 1982 |
[Trapidil after one year].
Topics: Anticoagulants; Arm; Arteriosclerosis; Brain Ischemia; Clinical Trials as Topic; Drug Evaluation; Hu | 1993 |
1 trial available for trapidil and Arteriosclerosis
| Article | Year |
|---|---|
Platelet and endothelial response with trapidil in patients with peripheral obliterative arteriopathy.
Topics: Aged; Arteriosclerosis; Blood Platelets; Double-Blind Method; Endothelins; Endothelium, Vascular; Fe | 1994 |
9 other studies available for trapidil and Arteriosclerosis
| Article | Year |
|---|---|
[Effect of trapidil on experimental hyperlipemia and atherosclerosis induced by cholesterol diet in SPF Japanese white rabbits].
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Cholesterol, Dietary; Diet, Atherogenic; Disease Models, | 1983 |
A new approach to the treatment of atherosclerosis and trapidil as an antagonist to platelet-derived growth factor.
Topics: Animals; Arteriosclerosis; Blood Platelets; Cell Division; Cell Transformation, Viral; Cells, Cultur | 1981 |
Evidence for "response to injury" hypothesis.
Topics: Animals; Arteriosclerosis; Blood Platelets; Carotid Arteries; Carotid Artery Injuries; Cell Division | 1982 |
PDGF-like growth factor from SV40-transformed smooth muscle cells promotes growth in an autocrine or paracrine manner.
Topics: Animals; Arteriosclerosis; Cell Division; Cell Transformation, Viral; Collagen; Cyclic AMP; Muscle, | 1994 |
Effect of trapidil on effector functions of monocytes related to atherosclerotic plaque.
Topics: Animals; Antibodies, Monoclonal; Arteriosclerosis; CD40 Antigens; CD40 Ligand; Cell Line; Chemokine | 2001 |
Influence of the trapidil derivative AR 12463 on serum and tissue lipids and development of aortic lesions during experimental atherosclerosis in rabbits.
Topics: Animals; Aorta; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Electrophoresis, Polyacrylamide | 1991 |
Trapidil in preventing restenosis after balloon angioplasty in the atherosclerotic rabbit.
Topics: Angioplasty, Balloon; Animals; Arteriosclerosis; Cell Division; Female; Iliac Artery; Male; Muscle, | 1990 |
Influence of drugs on the TXA2/PGI2 balance and on the atherogenic index in myocardial ischemia in dogs.
Topics: Animals; Antihypertensive Agents; Arteriosclerosis; Biomarkers; Coronary Disease; Dogs; Epoprostenol | 1988 |
Trapidil derivatives as potential antiatherosclerotic drugs.
Topics: Arteriosclerosis; Cholesterol; Cholesterol Esters; Collagen; Humans; In Vitro Techniques; Lipid Meta | 1987 |