Page last updated: 2024-08-22

tranylcypromine and Leucocythaemia

tranylcypromine has been researched along with Leucocythaemia in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alli, C; Bremberg, U; Cartic, S; Geitmann, M; Jordan, AM; Maiques-Diaz, A; McGonagle, AE; Mould, DP; Ogilvie, D; Somervaille, TCP; Spencer, GJ; Turlais, F1
Barth, J; Berg, T; Fulda, S; Greve, G; Haas, J; Hau, M; Haydn, T; Jung, M; Kürner, A; Lübbert, M; Lüdeke, S; Robaa, D; Schüle, R; Schulz-Fincke, J; Sippl, W; Willmann, D1
Botrugno, OA; Ciossani, G; Cirilli, R; Dessanti, P; Labella, D; Mai, A; Marrocco, B; Mattevi, A; Mercurio, C; Minucci, S; Monaldi, D; Rodriguez, V; Ruoppolo, G; Saponara, B; Tilset, M; Valente, S; Varasi, M; Vianello, P1

Other Studies

3 other study(ies) available for tranylcypromine and Leucocythaemia

ArticleYear
Development of (4-Cyanophenyl)glycine Derivatives as Reversible Inhibitors of Lysine Specific Demethylase 1.
    Journal of medicinal chemistry, 2017, 10-12, Volume: 60, Issue:19

    Topics: Antineoplastic Agents; Biomarkers; Cell Line, Tumor; Computer Simulation; Drug Design; Drug Discovery; Enzyme Inhibitors; Ether-A-Go-Go Potassium Channels; Glycine; High-Throughput Screening Assays; Histone Demethylases; Humans; Leukemia; Models, Molecular; Molecular Docking Simulation; Spiro Compounds; Structure-Activity Relationship; Tranylcypromine

2017
Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation.
    European journal of medicinal chemistry, 2018, Jan-20, Volume: 144

    Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Enzyme Inhibitors; Histone Demethylases; Humans; Leukemia; Mice; Models, Molecular; Monoamine Oxidase Inhibitors; Structure-Activity Relationship; Tranylcypromine

2018
Pure enantiomers of benzoylamino-tranylcypromine: LSD1 inhibition, gene modulation in human leukemia cells and effects on clonogenic potential of murine promyelocytic blasts.
    European journal of medicinal chemistry, 2015, Apr-13, Volume: 94

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Gene Expression Regulation, Leukemic; Histone Demethylases; Humans; Leukemia; Leukemia, Promyelocytic, Acute; Mice; Mice, Inbred Strains; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Tranylcypromine

2015