Page last updated: 2024-08-22

tranylcypromine and Disease Models, Animal

tranylcypromine has been researched along with Disease Models, Animal in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199010 (33.33)18.7374
1990's2 (6.67)18.2507
2000's5 (16.67)29.6817
2010's8 (26.67)24.3611
2020's5 (16.67)2.80

Authors

AuthorsStudies
Guo, HF; Jin, J; Li, ZR; Liu, ZY; Xie, ZS; Xue, ST; Yi, H; Zhang, L1
Chen, LZ; Huang, X; Liu, MM; Liu, XH; Ma, D; Shi, JB; Shu, HY; Wu, J; Yu, YL1
Ragu Varman, D; Rajan, KE; Sivasangari, K; Thangaleela, S1
Han, KM; Hoe, HS; Jeon, H; Jeon, SG; Jeong, YH; Kim, YG; Lee, H; Lee, JS; Lee, YH; Lin, Y; Park, H; Park, JH1
Barnstable, CJ; Imamura Kawasawa, Y; Popova, EY; Zhang, SS1
Bernstein, DI; Bosch-Marce, M; Bravo, FJ; Cardin, RD; Clement, C; Foster, TP; Hill, JM; Knipe, DM; Krause, PR; Kristie, TM; Lee, JS; Quenelle, DC; Raja, P; Vogel, JL1
DeSimone, J; Ibanez, V; Jagadeeswaran, R; Kouznetsova, T; Lavelle, D; Rivers, A; Ruiz, MA; Vaitkus, K1
Angelini, C; Baldini, A; Franzese, M; Fulcoli, FG; Liu, X; Zhang, Z1
Hayashi, H; Hino, S; Inoue, T; Iwao, K; Kawaji, T; Kirihara, T; Nakao, M; Tanihara, H; Tsutsumi, T1
Belluzzi, JD; Leslie, FM; Villégier, AS1
Blazevic, S; Colic, L; Culig, L; Hranilovic, D1
Burnett, A; Casero, RA; Chen, WC; Dick, JE; Dugas, M; Göllner, S; Hebestreit, K; Howell, L; Jin, L; Klein, HU; Marton, L; Mills, K; Minden, MD; Müller-Tidow, C; Petrie, K; Popescu, AC; Schenk, T; Wang, JC; Woster, P; Zelent, A1
Kasai, M; Kato, S; Nisijima, K; Shioda, K; Yoshino, T1
Dobbing, J; Pickard, FJ; Tricklebank, MD1
Lehmann, ML; Lin, Y; Quartermain, D; Stone, EA1
Gross, G; Groth, I; Jongen-Relo, A; Rex, A; Wicke, KM1
Bylund, DB; Happe, HK; Petty, F; Reed, AL1
Dulloo, AG; Miller, DS1
Katz, RJ; Roth, KA; Schmaltz, K1
Gard, PR; Mandy, A; Sutcliffe, MA1
Ha, T; Kesslak, JP; Ramirez, R; Russo-Neustadt, A1
Okuyama, S; Takamori, K; Yoshida, S1
Golda, V; Petr, R2
Jesberger, JA; Richardson, JS1
Kameyama, T; Nagasaka, M; Yamada, K1
Crawley, JN1
Fibiger, HC; McGeer, EG; Zis, AP1
Babington, RG; Wedeking, PW1
Davis, JM; Forbes, DJ; Glisson, SN; Himwich, WA; Magnusson, T; Stout, MA; Trusty, DM1

Other Studies

30 other study(ies) available for tranylcypromine and Disease Models, Animal

ArticleYear
Substituted benzothiophene and benzofuran derivatives as a novel class of bone morphogenetic Protein-2 upregulators: Synthesis, anti-osteoporosis efficacies in ovariectomized rats and a zebrafish model, and ADME properties.
    European journal of medicinal chemistry, 2020, Aug-15, Volume: 200

    Topics: Animals; Benzofurans; Bone Morphogenetic Protein 2; Caco-2 Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Mice; Mice, Inbred BALB C; Molecular Structure; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiophenes; Zebrafish

2020
Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis.
    European journal of medicinal chemistry, 2021, Mar-05, Volume: 213

    Topics: Administration, Oral; Animals; Arthritis; Cells, Cultured; Dimerization; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Development; Enzyme Inhibitors; Freund's Adjuvant; Humans; Lipopolysaccharides; Male; Mice; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; RAW 264.7 Cells; Structure-Activity Relationship

2021
Inhibition of monoamine oxidase attenuates social defeat-induced memory impairment in goldfish, (Carassius auratus): A possible involvement of synaptic proteins and BDNF.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2021, Volume: 239

    Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Goldfish; Memory Disorders; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Social Defeat; Synaptic Transmission; Tranylcypromine

2021
The MAO Inhibitor Tranylcypromine Alters LPS- and Aβ-Mediated Neuroinflammatory Responses in Wild-type Mice and a Mouse Model of AD.
    Cells, 2020, 08-28, Volume: 9, Issue:9

    Topics: Alzheimer Disease; Animals; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Mice; Monoamine Oxidase Inhibitors; Tranylcypromine

2020
Inhibition of Epigenetic Modifiers LSD1 and HDAC1 Blocks Rod Photoreceptor Death in Mouse Models of Retinitis Pigmentosa.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021, 08-04, Volume: 41, Issue:31

    Topics: Animals; Cell Death; Disease Models, Animal; Epigenesis, Genetic; Female; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Demethylases; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Retinal Rod Photoreceptor Cells; Retinitis Pigmentosa; Tranylcypromine

2021
Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes.
    Science translational medicine, 2014, Dec-03, Volume: 6, Issue:265

    Topics: Animals; Disease Models, Animal; Epigenesis, Genetic; Female; Genome, Viral; Guinea Pigs; Herpesviridae Infections; Histone Demethylases; Mice; Mice, Inbred BALB C; Monoamine Oxidase Inhibitors; Oxidoreductases, N-Demethylating; Phenotype; Protein Structure, Tertiary; Rabbits; Recurrence; Tranylcypromine; Vagina; Virus Activation; Virus Latency; Virus Replication; Virus Shedding

2014
RN-1, a potent and selective lysine-specific demethylase 1 inhibitor, increases γ-globin expression, F reticulocytes, and F cells in a sickle cell disease mouse model.
    Experimental hematology, 2015, Volume: 43, Issue:7

    Topics: Anemia, Sickle Cell; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Erythroid Precursor Cells; Erythropoiesis; Fetal Hemoglobin; gamma-Globins; Gene Expression Regulation; Hematopoietic Stem Cells; Histone Demethylases; Histones; Humans; Hydroxyurea; Methylation; Mice; Mice, Transgenic; Papio; Protein Processing, Post-Translational; Reticulocytes; Transgenes; Tranylcypromine; Tretinoin; U937 Cells

2015
Rebalancing gene haploinsufficiency in vivo by targeting chromatin.
    Nature communications, 2016, 06-03, Volume: 7

    Topics: Animals; Chromatin; DiGeorge Syndrome; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation; Haploinsufficiency; Histone Code; Histone Demethylases; Mice; Monoamine Oxidase Inhibitors; Mutation; T-Box Domain Proteins; Tranylcypromine

2016
Potential Neuroprotective Effects of an LSD1 Inhibitor in Retinal Ganglion Cells via p38 MAPK Activity.
    Investigative ophthalmology & visual science, 2016, 11-01, Volume: 57, Issue:14

    Topics: Animals; Apoptosis; Caspase 3; Cell Survival; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Histone Demethylases; Immunoblotting; Immunohistochemistry; Male; Monoamine Oxidase Inhibitors; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Retinal Degeneration; Retinal Ganglion Cells; RNA; Tranylcypromine

2016
Serotonergic mechanism underlying tranylcypromine enhancement of nicotine self-administration.
    Synapse (New York, N.Y.), 2011, Volume: 65, Issue:6

    Topics: Animals; Disease Models, Animal; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; Serotonin; Tobacco Use Disorder; Tranylcypromine; Up-Regulation

2011
Anxiety-like behavior and cognitive flexibility in adult rats perinatally exposed to increased serotonin concentrations.
    Behavioural brain research, 2012, Apr-21, Volume: 230, Issue:1

    Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Anxiety Disorders; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Male; Maze Learning; Monoamine Oxidase Inhibitors; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Serotonin; Sex Factors; Tranylcypromine; Tryptophan

2012
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia.
    Nature medicine, 2012, Mar-11, Volume: 18, Issue:4

    Topics: Animals; Antigens, CD34; Apoptosis; CD11b Antigen; Cell Differentiation; Cells, Cultured; Cytokines; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Female; Flow Cytometry; Gene Expression Regulation; Histone Demethylases; Humans; Leukemia, Myeloid, Acute; Lysine; Mice; Mice, Inbred NOD; Mice, SCID; RNA, Small Interfering; Stem Cell Factor; Time Factors; Transplants; Tranylcypromine; Tretinoin

2012
Risperidone attenuates the increase of extracellular nitric oxide and glutamate levels in serotonin syndrome animal models.
    Neuroscience letters, 2012, Oct-18, Volume: 528, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Clorgyline; Disease Models, Animal; Fluoxetine; Glutamic Acid; Male; Microdialysis; Monoamine Oxidase Inhibitors; Nitric Oxide; Rats, Wistar; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Syndrome; Tranylcypromine

2012
The effects of asphyxia on 5-hydroxytryptamine metabolism in the immature rat brain.
    Journal of neurochemistry, 1976, Volume: 27, Issue:5

    Topics: Animals; Asphyxia; Brain; Cold Temperature; Disease Models, Animal; Female; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Inbred Strains; Restraint, Physical; Resuscitation; Serotonin; Tranylcypromine

1976
Reduced evoked fos expression in activity-related brain regions in animal models of behavioral depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Aug-15, Volume: 31, Issue:6

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Depression; Desipramine; Disease Models, Animal; Dominance-Subordination; Freezing Reaction, Cataleptic; Galanin; Gene Expression Regulation; Male; Mice; Proto-Oncogene Proteins c-fos; Stress, Psychological; Swimming; Time Factors; Tranylcypromine

2007
The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants.
    Psychopharmacology, 2007, Volume: 195, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drugs, Investigational; Fluoxetine; Guinea Pigs; Injections, Intraperitoneal; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Paroxetine; Piperidines; Selective Serotonin Reuptake Inhibitors; Swimming; Tranylcypromine

2007
Juvenile rats in the forced-swim test model the human response to antidepressant treatment for pediatric depression.
    Psychopharmacology, 2008, Volume: 197, Issue:3

    Topics: Adolescent; Age Factors; Animals; Antidepressive Agents; Child; Citalopram; Depressive Disorder; Desipramine; Disease Models, Animal; Escape Reaction; Fluoxetine; Helplessness, Learned; Humans; Imipramine; Injections, Intraperitoneal; Male; Motivation; Rats; Rats, Sprague-Dawley; Swimming; Tranylcypromine

2008
Thermogenic drugs for the treatment of obesity: sympathetic stimulants in animal models.
    The British journal of nutrition, 1984, Volume: 52, Issue:2

    Topics: Animals; Body Temperature Regulation; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Ephedrine; Female; Male; Mice; Mice, Inbred Strains; Mice, Obese; Obesity; Rats; Rats, Zucker; Stimulation, Chemical; Sympathomimetics; Tranylcypromine

1984
Amphetamine and tranylcypromine in an animal model of depression: pharmacological specificity of the reversal effect.
    Neuroscience and biobehavioral reviews, 1981,Summer, Volume: 5, Issue:2

    Topics: Amphetamine; Animals; Chronic Disease; Corticosterone; Defecation; Depression; Disease Models, Animal; Humans; Male; Motor Activity; Rats; Reaction Time; Tranylcypromine

1981
Evidence of a possible role of altered angiotensin function in the treatment, but not etiology, of depression.
    Biological psychiatry, 1999, Apr-15, Volume: 45, Issue:8

    Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Binding Sites; Cell Culture Techniques; Depression, Postpartum; Desipramine; Disease Models, Animal; Female; Fluoxetine; Humans; Losartan; Male; Mice; Receptors, Angiotensin; Tranylcypromine

1999
Physical activity-antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model.
    Behavioural brain research, 2001, Apr-08, Volume: 120, Issue:1

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Combined Modality Therapy; Depression; Disease Models, Animal; Hippocampus; In Situ Hybridization; Male; Physical Conditioning, Animal; Physical Exertion; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tranylcypromine; Up-Regulation

2001
Repeated treatment with imipramine, fluvoxamine and tranylcypromine decreases the number of escape failures by activating dopaminergic systems in a rat learned helplessness test.
    Life sciences, 2001, Sep-07, Volume: 69, Issue:16

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antidepressive Agents; Benzazepines; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Escape Reaction; Fluvoxamine; Helplessness, Learned; Imipramine; Male; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine; Sulpiride; Tetrahydronaphthalenes; Tranylcypromine

2001
Validation of aversion towards open space and height as a measure of anxiety in the genetically based animal model of depression.
    Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove, 1990, Volume: 33, Issue:5

    Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Depressive Disorder; Diazepam; Disease Models, Animal; Female; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Tranylcypromine

1990
Motor depression as a consequence of inescapable shocking and a reactivity to the electric shocks: the acute tranylcypromin treatment.
    Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove, 1986, Volume: 29, Issue:4-5

    Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Electroshock; Female; Helplessness, Learned; Male; Motor Activity; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Specific Pathogen-Free Organisms; Tranylcypromine

1986
Effects of antidepressant drugs on the behavior of olfactory bulbectomized and sham-operated rats.
    Behavioral neuroscience, 1986, Volume: 100, Issue:2

    Topics: 11-Hydroxycorticosteroids; Amitriptyline; Animals; Antidepressive Agents; Brain Diseases; Depressive Disorder; Disease Models, Animal; Iprindole; Male; Mianserin; Olfactory Bulb; Rats; Tranylcypromine

1986
Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice.
    Neuropharmacology, 1985, Volume: 24, Issue:4

    Topics: Acridines; Amitriptyline; Animals; Antidepressive Agents; Depressive Disorder; Desipramine; Diphenhydramine; Disease Models, Animal; Electroshock; Ethanol; Humans; Imipramine; Male; Maprotiline; Mianserin; Mice; Motor Activity; Nialamide; Pargyline; Tranylcypromine

1985
A monoamine oxidase inhibitor reverses the 'separation syndrome' in a new hamster separation model of depression.
    European journal of pharmacology, 1985, May-28, Volume: 112, Issue:1

    Topics: Animals; Cricetinae; Depression; Disease Models, Animal; Exploratory Behavior; Female; Humans; Male; Monoamine Oxidase Inhibitors; Pair Bond; Sexual Behavior, Animal; Social Isolation; Time Factors; Tranylcypromine

1985
Feeding and drinking deficits after 6-hydroxydopamine administration in the rat: similarities to the lateral hypothalamic syndrome.
    Brain research, 1973, May-30, Volume: 55, Issue:1

    Topics: Amphetamine; Animals; Catecholamines; Corpus Striatum; Disease Models, Animal; Drinking Behavior; Feeding and Eating Disorders; Feeding Behavior; Fenfluramine; Humans; Hydroxydopamines; Hypothalamus; Male; Mesencephalon; Quinine; Rats; Substantia Nigra; Tranylcypromine; Tyrosine 3-Monooxygenase; Water-Electrolyte Balance

1973
The influence of cinanserin and selected pharmacologic agents on experimental allergic encephalomyelitis (EAE).
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:2

    Topics: 5-Hydroxytryptophan; Amphetamine; Anilides; Animals; Azathioprine; Body Weight; Chlorpheniramine; Cinnamates; Cyclophosphamide; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Fenclonine; Immunosuppressive Agents; Mercaptopurine; Methylamines; Methysergide; Paralysis; Rats; Reserpine; Serotonin Antagonists; Tetrabenazine; Time Factors; Tranylcypromine

1971
Indole metabolism and behavior in dog.
    Biological psychiatry, 1972, Volume: 4, Issue:1

    Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Behavior, Animal; Brain; Brain Chemistry; Depression; Disease Models, Animal; Dogs; Electrodes, Implanted; Electroencephalography; Evaluation Studies as Topic; Female; Housing, Animal; Humans; Indoles; Male; Portacaval Shunt, Surgical; Tranylcypromine; Tryptophan

1972